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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.636
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.598
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.586
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.570
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.559
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.541
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441