scPDB - Distribution of Binding site Similarity values of 1stc entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1stc	STU	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1stc	STU	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	1.000
4c34	STU	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.607
3amb	VX6	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.458
3say	OFT	Glycogen synthase kinase-3 beta	2.7.11.26	0.441