sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1sqf | SAM | Ribosomal RNA small subunit methyltransferase B | 2.1.1.176 | 1.000 | |
| 4fzv | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.598 | |
| 2yxl | SFG | 450aa long hypothetical fmu protein | / | 0.546 | |
| 3m6v | SAM | Ribosomal RNA small subunit methyltransferase F | / | 0.539 | |
| 4fp9 | SAM | 5-methylcytosine rRNA methyltransferase NSUN4 | 2.1.1 | 0.522 | |
| 3m6w | SAM | Ribosomal RNA small subunit methyltransferase F | / | 0.509 | |
| 3a4t | SFG | tRNA (cytosine(48)-C(5))-methyltransferase | 2.1.1 | 0.478 | |
| 3ssm | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.451 | |
| 5a3c | NAD | SIR2 family protein | / | 0.447 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.440 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.440 |