scPDB - Distribution of Binding site Similarity values of 1sir entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1sir	NBC	Glutaryl-CoA dehydrogenase, mitochondrial	1.3.8.6

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1sir	NBC	Glutaryl-CoA dehydrogenase, mitochondrial	1.3.8.6	1.000
2r0n	TGC	Glutaryl-CoA dehydrogenase, mitochondrial	1.3.8.6	0.570
2ix5	CAA	Acyl-coenzyme A oxidase 4, peroxisomal	1.3.3.6	0.480
1rx0	2MC	Isobutyryl-CoA dehydrogenase, mitochondrial	1.3.99	0.451
3mpi	GRA	Glutaryl-CoA dehydrogenase	1.3.99.32	0.442