sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1sg9 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1sg9 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 1.000 | |
| 1nv8 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.628 | |
| 1nv9 | SAH | Release factor glutamine methyltransferase | 2.1.1.297 | 0.617 | |
| 1vq1 | SAM | Release factor glutamine methyltransferase | 2.1.1.297 | 0.567 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.483 | |
| 2np7 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.474 | |
| 5bxy | SAH | Putative RNA methylase family UPF0020 | / | 0.466 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.465 | |
| 2ih2 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.462 | |
| 2wpx | ACO | Orf14 | / | 0.454 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.453 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.453 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.452 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.450 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.449 | |
| 1ptj | SND | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.449 | |
| 2yx1 | SFG | tRNA (guanine(37)-N1)-methyltransferase Trm5b | 2.1.1.228 | 0.449 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.449 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.448 | |
| 3egv | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.445 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.445 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.445 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.445 | |
| 4da4 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.444 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.443 | |
| 1g38 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.442 | |
| 3sdi | 3SD | Proteasome subunit beta type-5 | 3.4.25.1 | 0.442 | |
| 3sdi | 3SD | Proteasome subunit beta type-6 | 3.4.25.1 | 0.442 | |
| 3uj7 | SAM | Phosphoethanolamine N-methyltransferase | / | 0.442 | |
| 4ctj | SAM | Genome polyprotein | / | 0.441 | |
| 4kvz | SAH | PtnL protein | / | 0.441 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.440 |