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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1s63778Protein farnesyltransferase subunit beta2.5.1.58

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1s63778Protein farnesyltransferase subunit beta2.5.1.581.000
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.815
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.750
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.735
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.651
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.651
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.650
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.646
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.615
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.612
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.606
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.603
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.550
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.549
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.522
3q7fED2Uncharacterized protein/0.514
3sfy3FYUncharacterized protein/0.514
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.503
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.503
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.499
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.497
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.495
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.494
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.462
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.462
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.461
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.451
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.446