sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 1.000 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.703 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.626 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.624 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.545 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.501 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.496 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.489 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.484 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.476 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.469 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.468 | |
| 4kub | COA | Uncharacterized protein | / | 0.467 | |
| 4kvm | SER_ALA_SER_GLU_1XE | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.467 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.465 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.465 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.463 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.462 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.459 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.457 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.457 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.456 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.456 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.455 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.455 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.455 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.450 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.449 | |
| 4jxr | ACO | Acetyltransferase | / | 0.449 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.447 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.446 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.441 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.440 |