scPDB - Distribution of Binding site Similarity values of 1s3v entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1s3v	TQD	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	1.000
1mvt	DTM	Dihydrofolate reductase	1.5.1.3	0.678
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.611
3s7a	684	Dihydrofolate reductase	1.5.1.3	0.587
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.585
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.583
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.557
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.509
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.508
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.505
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.493
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.488
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.476
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.476
1u71	MXA	Dihydrofolate reductase	1.5.1.3	0.475
3s3v	TOP	Dihydrofolate reductase	1.5.1.3	0.467
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.464
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.461
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.457
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.450
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.448
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.446
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.445
4keb	FOL	Dihydrofolate reductase	1.5.1.3	0.444