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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1rw8580TGF-beta receptor type-12.7.11.30

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1rw8580TGF-beta receptor type-12.7.11.301.000
2wotZZGTGF-beta receptor type-12.7.11.300.589
5e8wSTUTGF-beta receptor type-12.7.11.300.584
3hmm855TGF-beta receptor type-12.7.11.300.570
4dymIYZActivin receptor type-12.7.11.300.570
3gxlQIGTGF-beta receptor type-12.7.11.300.567
3mtfA3FActivin receptor type-12.7.11.300.565
1bygSTUTyrosine-protein kinase CSK/0.561
5e92ANPTGF-beta receptor type-22.7.11.300.560
1u4dDBQActivated CDC42 kinase 1/0.551
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.543
1vjy460TGF-beta receptor type-12.7.11.300.539
1py5PY1TGF-beta receptor type-12.7.11.300.538
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.528
4c02TAKActivin receptor type-12.7.11.300.522
1u54ACPActivated CDC42 kinase 1/0.521
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.518
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.517
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.517
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.517
4riyADPEpidermal growth factor receptor2.7.10.10.517
5e8xSTUTGF-beta receptor type-12.7.11.300.517
4gk2L66Ephrin type-A receptor 32.7.10.10.515
3oom507Activin receptor type-12.7.11.300.514
2qo9ANPEphrin type-A receptor 32.7.10.10.510
2wouZZFTGF-beta receptor type-12.7.11.300.510
3vs3VSETyrosine-protein kinase HCK2.7.10.20.506
4gk3L87Ephrin type-A receptor 32.7.10.10.506
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.504
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.504
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.504
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.502
3vryB43Tyrosine-protein kinase HCK2.7.10.20.502
3zewSTUEphrin type-B receptor 42.7.10.10.502
4hjoAQ4Epidermal growth factor receptor2.7.10.10.502
3w32W32Epidermal growth factor receptor2.7.10.10.501
4y95746Tyrosine-protein kinase/0.501
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.499
3a60STURibosomal protein S6 kinase beta-12.7.11.10.498
3gubGUBDeath-associated protein kinase 12.7.11.10.498
3zh8C58Protein kinase C iota type2.7.11.130.498
4c58824Cyclin-G-associated kinase2.7.11.10.497
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.496
4lopSB4Mitogen-activated protein kinase 14/0.496
2j5xGSPADP-ribosylation factor 6/0.495
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.494
3nbvANPKetohexokinase/0.493
4yuqKS1Calmodulin-like domain protein kinase/0.493
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.492
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.492
2y6o1N1Ephrin type-A receptor 42.7.10.10.492
3gi6D78Gag-Pol polyprotein/0.492
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.491
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.489
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.489
4kb81QOCasein kinase I isoform delta2.7.11.10.487
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.486
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.486
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.486
4jq8KJ8Epidermal growth factor receptor2.7.10.10.486
4u0mGTPCyclic GMP-AMP synthase/0.486
1jld0PPGag-Pol polyprotein/0.485
4i22IREEpidermal growth factor receptor2.7.10.10.485
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.484
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.483
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.483
1t7j478Gag-Pol polyprotein3.4.23.160.482
3ggfGVDSerine/threonine-protein kinase 26/0.482
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.482
1sduMK1Gag-Pol polyprotein3.4.23.160.481
2vx17X8Ephrin type-B receptor 42.7.10.10.481
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.481
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.481
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.480
2vwz7X6Ephrin type-B receptor 42.7.10.10.480
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.480
3k5uPFQAurora kinase A2.7.11.10.480
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.479
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.479
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.478
4bgg844Activin receptor type-12.7.11.300.478
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.478
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.477
3ekx1UNGag-Pol polyprotein3.4.23.160.477
3rvg17PTyrosine-protein kinase JAK2/0.477
3w33W19Epidermal growth factor receptor2.7.10.10.477
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.477
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.477
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
2hk51BMTyrosine-protein kinase HCK2.7.10.20.476
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.476
4kin1M8Mitogen-activated protein kinase 14/0.476
4kwhNAPReductase homolog/0.476
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.475
2dwbANPAurora kinase A2.7.11.10.475
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.475
3uyt0CKCasein kinase I isoform delta2.7.11.10.475
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.475
1bsvNDPGDP-L-fucose synthase/0.474
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.474
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.474
2qi0MZ3Gag-Pol polyprotein/0.474
3l8p0CEAngiopoietin-1 receptor2.7.10.10.474
4e4m0NHTyrosine-protein kinase JAK2/0.474
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.474
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.474
1cjtFOKAdenylate cyclase type 2/0.473
1cjtFOKAdenylate cyclase type 5/0.473
2nnkROCProtease/0.473
3sf6FDAGlutaryl-CoA dehydrogenase/0.473
4gmy0X5Tyrosine-protein kinase JAK2/0.473
4id71G0Activated CDC42 kinase 1/0.473
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.472
2vwy7X5Ephrin type-B receptor 42.7.10.10.472
3eb0DRKUncharacterized protein/0.472
3zptM8YGag-Pol polyprotein3.4.23.160.472
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.472
4u7wNDPMxaA/0.472
1kkq471Peroxisome proliferator-activated receptor alpha/0.471
2b7zMK1Gag-Pol polyprotein/0.471
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.471
3cukFADD-amino-acid oxidase1.4.3.30.471
3el51UNGag-Pol polyprotein/0.471
3sheI85MAP kinase-activated protein kinase 32.7.11.10.471
4fod0UVALK tyrosine kinase receptor2.7.10.10.471
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.471
4loqSB4Mitogen-activated protein kinase 14/0.471
2qi3MZ5Gag-Pol polyprotein/0.470
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.470
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.470
3ixp834Ecdysone receptor/0.470
4j55031Gag-Pol polyprotein3.4.23.160.470
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.470
3d1yROCGag-Pol polyprotein3.4.23.160.469
3em6017Gag-Pol polyprotein3.4.23.160.469
3qu0X40Cyclin-dependent kinase 22.7.11.220.469
3sa8K83Protease/0.469
3vt8YI3Vitamin D3 receptor/0.469
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.469
4zseANPEpidermal growth factor receptor2.7.10.10.469
1dhrNADDihydropteridine reductase1.5.1.340.468
1t7i017Gag-Pol polyprotein3.4.23.160.468
2eufLQQCyclin-dependent kinase 62.7.11.220.468
2izuP01Casein kinase I isoform gamma-32.7.11.10.468
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.468
2qo7ANPEphrin type-A receptor 32.7.10.10.468
3gu83GUDeath-associated protein kinase 12.7.11.10.468
3i60E86Mitogen-activated protein kinase 12.7.11.240.468
4aacAAVMitogen-activated protein kinase 14/0.468
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.468
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.468
1zz2B11Mitogen-activated protein kinase 14/0.467
2itnANPEpidermal growth factor receptor2.7.10.10.467
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.467
2qd7065Gag-Pol polyprotein3.4.23.160.467
3sacAF8Protease/0.467
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.467
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.467
4jr3KJREpidermal growth factor receptor2.7.10.10.467
4wkqIREEpidermal growth factor receptor2.7.10.10.467
2balPQAMitogen-activated protein kinase 14/0.466
2du8FADD-amino-acid oxidase1.4.3.30.466
3lshFADPyranose 2-oxidase/0.466
3pqbVGPPutative oxidoreductase/0.466
3zep1NXTyrosine-protein kinase JAK32.7.10.20.466
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.466
4yaiNAIC alpha-dehydrogenase/0.466
1u28NADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.465
2pwlACPFibroblast growth factor receptor 2/0.465
3pwrROCGag-Pol polyprotein3.4.23.160.465
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.465
3sabF78Protease/0.465
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.465
4qmpDKISerine/threonine-protein kinase 242.7.11.10.465
1adfTADAlcohol dehydrogenase E chain1.1.1.10.464
2xneASHAurora kinase A2.7.11.10.464
3sa4F72Protease/0.464
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.464
4hvg19QTyrosine-protein kinase JAK32.7.10.20.464
4hvh19RTyrosine-protein kinase JAK32.7.10.20.464
4jq7KJQEpidermal growth factor receptor2.7.10.10.464
4kba1QMCasein kinase I isoform delta2.7.11.10.464
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.464
1ppjANYCytochrome b/0.463
1rl8RITGag-Pol polyprotein3.4.23.160.463
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.463
3il1B5DGlutamate receptor 2/0.463
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.463
3nduROCGag-Pol polyprotein3.4.23.160.463
3nwxKVSGag-Pol polyprotein3.4.23.160.463
3vt7VDXVitamin D3 receptor/0.463
4bb432WEphrin type-B receptor 42.7.10.10.463
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.463
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1tqf32PBeta-secretase 13.4.23.460.462
1xkkFMMEpidermal growth factor receptor2.7.10.10.462
2c27ACOMycothiol acetyltransferase2.3.1.1890.462
2f3kRO1Protease/0.462
2q7vFADThioredoxin reductase/0.462
3ttp017Gag-Pol polyprotein3.4.23.160.462
4btkDTQTau-tubulin kinase 12.7.11.10.462
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.462
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.462
2c6tDT5Cyclin-dependent kinase 22.7.11.220.461
2vwu7X1Ephrin type-B receptor 42.7.10.10.461
2vwx7X4Ephrin type-B receptor 42.7.10.10.461
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.461
3hx4ANPCalmodulin-domain protein kinase 1/0.461
3poz03PEpidermal growth factor receptor2.7.10.10.461
4aqc88ATyrosine-protein kinase JAK2/0.461
4foc0UUALK tyrosine kinase receptor2.7.10.10.461
4xgxADPFAD:protein FMN transferase/0.461
1gih1PUCyclin-dependent kinase 22.7.11.220.460
1iziQ50Gag-Pol polyprotein3.4.23.160.460
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
1xddAAYIntegrin alpha-L/0.460
2c29NAPDihydroflavonol 4-reductase/0.460
3el4ROCGag-Pol polyprotein3.4.23.160.460
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.460
3fln3FNMitogen-activated protein kinase 14/0.460
3oxcROCProtease/0.460
3uzp0CKCasein kinase I isoform delta2.7.11.10.460
3vjoANPEpidermal growth factor receptor2.7.10.10.460
3vs1VSATyrosine-protein kinase HCK2.7.10.20.460
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4dfrMTXDihydrofolate reductase1.5.1.30.460
4fob0USALK tyrosine kinase receptor2.7.10.10.460
4i8zG08Gag-Pol polyprotein3.4.23.160.460
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.460
4ji91M3Tyrosine-protein kinase JAK2/0.460
5hwsNAP2-dehydropantoate 2-reductase/0.460
1hvlA76Gag-Pol polyprotein/0.459
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.459
2q54MU1Protease/0.459
2q5g1FAPeroxisome proliferator-activated receptor delta/0.459
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.459
3efwAK8Aurora kinase A2.7.11.10.459
3sa755AProtease/0.459
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.459
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.459
1g35AHFGag-Pol polyprotein3.4.23.160.458
1y0s331Peroxisome proliferator-activated receptor delta/0.458
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.458
2itvANPEpidermal growth factor receptor2.7.10.10.458
2qi7MZ9Gag-Pol polyprotein/0.458
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.458
3a62STURibosomal protein S6 kinase beta-12.7.11.10.458
3k4vROCGag-Pol polyprotein3.4.23.160.458
3rnnRNNGlutamate receptor 2/0.458
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.458
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.458
4j97ACPFibroblast growth factor receptor 2/0.458
4uyf73BBromodomain-containing protein 2/0.458
1hsgMK1Gag-Pol polyprotein/0.457
1meuDMPGag-Pol polyprotein3.4.23.160.457
1nhhANPDNA mismatch repair protein MutL/0.457
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.457
2psvMUVProtease/0.457
2xyuQ9GEphrin type-A receptor 42.7.10.10.457
2ya3J7V5'-AMP-activated protein kinase subunit gamma-1/0.457
3oqkS52Renin3.4.23.150.457
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.457
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
4fv7E94Mitogen-activated protein kinase 12.7.11.240.457
4y8wSTRSteroid 21-hydroxylase/0.457
1bw9NADPhenylalanine dehydrogenase/0.456
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.456
1oiyN41Cyclin-dependent kinase 22.7.11.220.456
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
2fzwNADAlcohol dehydrogenase class-31.1.1.10.456
2henADPEphrin type-B receptor 22.7.10.10.456
2hk9NAPShikimate dehydrogenase (NADP(+))/0.456
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.456
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
2itpAEEEpidermal growth factor receptor2.7.10.10.456
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.456
2r43G3GGag-Pol polyprotein3.4.23.160.456
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
2xa4AZ5Tyrosine-protein kinase JAK2/0.456
2y9qANPMitogen-activated protein kinase 12.7.11.240.456
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.456
3mnrSD1Heat shock protein HSP 90-alpha/0.456
3so9017Pol protein/0.456
3t2zFADSulfide-quinone reductase/0.456
3t3c017Gag-Pol polyprotein3.4.23.160.456
3tqhNDPQuinone oxidoreductase/0.456
3ttiKBIMitogen-activated protein kinase 102.7.11.240.456
4gg70J8Hepatocyte growth factor receptor2.7.10.10.456
4hvi19STyrosine-protein kinase JAK32.7.10.20.456
4looSB4Mitogen-activated protein kinase 14/0.456
4ly91YYGlucokinase regulatory protein/0.456
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1jpaANPEphrin type-B receptor 22.7.10.10.455
2excJNKMitogen-activated protein kinase 102.7.11.240.455
2fdd385Pol protein/0.455
2hog710Serine/threonine-protein kinase Chk12.7.11.10.455
2o0uC0MMitogen-activated protein kinase 102.7.11.240.455
2p3a3TLPol protein/0.455
2qhyMZ1Gag-Pol polyprotein/0.455
2vojNADAlanine dehydrogenase1.4.1.10.455
2vx07X7Ephrin type-B receptor 42.7.10.10.455
2znq401Peroxisome proliferator-activated receptor delta/0.455
3fp0FP015-O-acetyltransferase/0.455
3q5kD1UHeat shock protein 83-1/0.455
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.455
3umoATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.455
3vt9YI4Vitamin D3 receptor/0.455
3w2sW2REpidermal growth factor receptor2.7.10.10.455
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.455
4g2fC07Ephrin type-A receptor 32.7.10.10.455
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.455
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.455
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.455
4yswFADXanthine dehydrogenase/oxidase/0.455
1hxbROCGag-Pol polyprotein3.4.23.160.454
1iyzNDPProbable quinone oxidoreductase/0.454
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.454
2f8g017Gag-Pol polyprotein3.4.23.160.454
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.454
2pyn1UNGag-Pol polyprotein3.4.23.160.454
2rg6287Mitogen-activated protein kinase 14/0.454
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
3hwrNDP2-dehydropantoate 2-reductase/0.454
3hz137DHeat shock protein HSP 90-alpha/0.454
3le62BZCyclin-dependent kinase 22.7.11.220.454
3sa323XProtease/0.454
4cukNAID-lactate dehydrogenase/0.454
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.454
1gqtACPRibokinase/0.453
1hbvGANGag-Pol polyprotein/0.453
1ia1NDPDihydrofolate reductase1.5.1.30.453
1phhFADp-hydroxybenzoate hydroxylase/0.453
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.453
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.453
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.453
2yboSAHMethyltransferase/0.453
3crzFADFerredoxin--NADP+ reductase/0.453
3ih0ANPUncharacterized sugar kinase PH14592.7.10.453
3saa77FProtease/0.453
3t113T1Gag-Pol polyprotein3.4.23.160.453
4i231C9Epidermal growth factor receptor2.7.10.10.453
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1csnATPCasein kinase I homolog 12.7.11.10.452
2aquDR7Gag-Pol polyprotein3.4.23.160.452
2bxmIMNSerum albumin/0.452
2i0dMUTProtease/0.452
2ieo017Protease/0.452
2itqITQEpidermal growth factor receptor2.7.10.10.452
2izrBRKCasein kinase I isoform gamma-32.7.11.10.452
2pym1UNGag-Pol polyprotein3.4.23.160.452
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.452
3cid318Beta-secretase 13.4.23.460.452
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.452
3ekqROCGag-Pol polyprotein3.4.23.160.452
3ekt017Gag-Pol polyprotein3.4.23.160.452
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.452
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.452
4ivd15TTyrosine-protein kinase JAK1/0.452
4j5j478Gag-Pol polyprotein3.4.23.160.452
4nh82LCHeat shock protein HSP 90-alpha/0.452
1b16NAQAlcohol dehydrogenase1.1.1.10.451
1hosPHPGag-Pol polyprotein/0.451
1ivq0PXGag-Pol polyprotein/0.451
1zemNADXylitol dehydrogenase/0.451
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.451
2hw1ANPKetohexokinase/0.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
2qi4MZ6Gag-Pol polyprotein/0.451
2xvdAS6Ephrin type-B receptor 42.7.10.10.451
3ddqRRCCyclin-dependent kinase 22.7.11.220.451
3ekp478Gag-Pol polyprotein3.4.23.160.451
3nwq2NCGag-Pol polyprotein3.4.23.160.451
3nxe2NCProtease/0.451
4a6nFADTetX family tetracycline inactivation enzyme/0.451
4dqf017Gag-Pol polyprotein/0.451
4e6d0NUTyrosine-protein kinase JAK2/0.451
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
4njvRITProtease/0.451
4plpNADHomospermidine synthase2.5.1.440.451
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.451
4yagNAIC alpha-dehydrogenase/0.451
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.451
5drdATPAurora kinase A2.7.11.10.451
1fg62NCGag-Pol polyprotein3.4.23.160.450
1fg80Q4Gag-Pol polyprotein3.4.23.160.450
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.450
1m78NDPDihydrofolate reductase1.5.1.30.450
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.450
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
2bkzSBCCyclin-dependent kinase 22.7.11.220.450
2uzlC94Cyclin-dependent kinase 22.7.11.220.450
3hl7I47Mitogen-activated protein kinase 14/0.450
3o9aK14Pol polyprotein/0.450
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
3sm2478Putative gag-pro-pol polyprotein/0.450
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.450
4ye3G04Gag-Pol polyprotein3.4.23.160.450
1ae1NAPTropinone reductase 1/0.449
1d4sTPVGag-Pol polyprotein3.4.23.160.449
1fwkADPHomoserine kinase2.7.1.390.449
2hcdBIVVitamin D3 receptor A/0.449
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.449
2i4xKGQProtease/0.449
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.449
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.449
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.449
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.449
4u03GTPCyclic GMP-AMP synthase/0.449
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.449
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1fxsNAPGDP-L-fucose synthase/0.448
1khrVIRStreptogramin A acetyltransferase2.3.10.448
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.448
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.448
2ittAEEEpidermal growth factor receptor2.7.10.10.448
2of4979Tyrosine-protein kinase Lck2.7.10.20.448
3hz5Z64Heat shock protein HSP 90-alpha/0.448
3hzc2NCProtease/0.448
3mdmFJZCholesterol 24-hydroxylase/0.448
3r8lZ30Cyclin-dependent kinase 22.7.11.220.448
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.448
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.448
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.448
4o701QKBromodomain-containing protein 4/0.448
4y93746Tyrosine-protein kinase/0.448
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.448
4zohFADPutative oxidoreductase FAD-binding subunit/0.448
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.448
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.448
1bwaXV6Gag-Pol polyprotein3.4.23.160.447
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.447
1tj0FADBifunctional protein PutA1.5.5.20.447
1zmdNAIDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.447
2eb3ANPEpidermal growth factor receptor2.7.10.10.447
2gtnLIEMitogen-activated protein kinase 14/0.447
2idw017Protease/0.447
2iw84SPCyclin-dependent kinase 22.7.11.220.447
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.447
2pvnP63Casein kinase II subunit alpha2.7.11.10.447
3k4nFADPyranose 2-oxidase/0.447
3kf7L9GMitogen-activated protein kinase 14/0.447
3kfr3TLGag-Pol polyprotein/0.447
3vf7031Gag-Pol polyprotein3.4.23.160.447
4a9uA9USerine/threonine-protein kinase Chk22.7.11.10.447
4c62XWWTyrosine-protein kinase JAK2/0.447
4eok4SPCyclin-dependent kinase 22.7.11.220.447
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.447
4ia2BIVVitamin D3 receptor A/0.447
4iva1J5Tyrosine-protein kinase JAK2/0.447
4kip1R9Mitogen-activated protein kinase 14/0.447
4nxvGDPMitochondrial dynamics protein MID51/0.447
5dr9SKEAurora kinase A2.7.11.10.447
5dt3ATPAurora kinase A2.7.11.10.447
5f8eSAHPossible transcriptional regulatory protein/0.447
1ec3MS3Gag-Pol polyprotein3.4.23.160.446
1eh4IC1Casein kinase I homolog 12.7.11.10.446
1ma0NADAlcohol dehydrogenase class-31.1.1.10.446
1p0hACOMycothiol acetyltransferase2.3.1.1890.446
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1t3r017Gag-Pol polyprotein3.4.23.160.446
1uy6PU3Heat shock protein HSP 90-alpha/0.446
1x7hNDPPutative ketoacyl reductase1.3.10.446
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.446
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.446
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.446
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.446
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.446
2iwsNP4ATP-dependent molecular chaperone HSP82/0.446
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.446
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.446
2vzzSCAPutative succinyl-CoA transferase Rv0802c2.8.30.446
2wihP48Cyclin-dependent kinase 22.7.11.220.446
3a1nNADNDP-sugar epimerase/0.446
3ac2KSETyrosine-protein kinase Lck2.7.10.20.446
3biz61EWee1-like protein kinase2.7.10.20.446
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.446
3dmeFADPutative conserved exported protein/0.446
3gi5K62Gag-Pol polyprotein/0.446
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.446
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.446
3oroAGSSerine/threonine protein kinase/0.446
3ttjJBIMitogen-activated protein kinase 102.7.11.240.446
3zuyTCHTransporter/0.446
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.446
4ei40Q2Tyrosine-protein kinase JAK1/0.446
4k6z1Q3Tyrosine-protein kinase JAK1/0.446
4qgiROCGag-Pol polyprotein3.4.23.160.446
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
5dnrATPAurora kinase A2.7.11.10.446
1aq1STUCyclin-dependent kinase 22.7.11.220.445
1b15NAEAlcohol dehydrogenase1.1.1.10.445
1bwsNDPGDP-L-fucose synthase/0.445
1c6x3INProtease/0.445
1fgc2NCGag-Pol polyprotein3.4.23.160.445
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.445
1m0b0ZQGag-Pol polyprotein3.4.23.160.445
1mq4ADPAurora kinase A2.7.11.10.445
1v0pPVBCell division control protein 2 homolog2.7.11.220.445
1xjdSTUProtein kinase C theta type2.7.11.130.445
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.445
2nnpROCProtease/0.445
2p33J07Mitogen-activated protein kinase 102.7.11.240.445
2p3c3TLProtease/0.445
2vgoAD5Aurora kinase B-A2.7.11.10.445
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.445
2zybKSLTyrosine-protein kinase Lck2.7.10.20.445
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.445
3cic316Beta-secretase 13.4.23.460.445
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.445
3i2l2NCProtease/0.445
3ik6HCZGlutamate receptor 2/0.445
3o9cK20Pol polyprotein/0.445
3sa5A69Protease/0.445
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
4g1z0VPVitamin D3 receptor A/0.445
4j54G52Gag-Pol polyprotein3.4.23.160.445
4q71FADBifunctional protein PutA/0.445
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.445
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.445
4z24FADPutative GMC-type oxidoreductase R13510.445
1k7l544Peroxisome proliferator-activated receptor alpha/0.444
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.444
1nfbNADInosine-5'-monophosphate dehydrogenase 2/0.444
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.444
1nytNAPShikimate dehydrogenase (NADP(+))/0.444
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.444
2in6839Wee1-like protein kinase2.7.10.20.444
2om9AJAPeroxisome proliferator-activated receptor gamma/0.444
2q631UNGag-Pol polyprotein3.4.23.160.444
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.444
2qi5MZ7Gag-Pol polyprotein/0.444
2qoqANPEphrin type-A receptor 32.7.10.10.444
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3dckKVIProtease/0.444
3i6oGR6Gag-Pol polyprotein3.4.23.160.444
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.444
3ksdNADGlyceraldehyde-3-phosphate dehydrogenase 1/0.444
3livE16Protease/0.444
3lsiFADPyranose 2-oxidase/0.444
3lzs017Gag-Pol polyprotein3.4.23.160.444
3rpv26ZCyclin-dependent kinase 22.7.11.220.444
3s56ROCProtease/0.444
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.444
4aotGW8Serine/threonine-protein kinase 102.7.11.10.444
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.444
4dgnLU2Casein kinase II subunit alpha2.7.11.10.444
4f650S9Fibroblast growth factor receptor 1/0.444
4fv6E57Mitogen-activated protein kinase 12.7.11.240.444
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.444
4i02CMPcAMP-activated global transcriptional regulator CRP/0.444
4nifANPMitogen-activated protein kinase 12.7.11.240.444
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.444
4qecNAPElxO/0.444
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.444
5dt4ATPAurora kinase A2.7.11.10.444
1c6zROCProtease/0.443
1di8DTQCyclin-dependent kinase 22.7.11.220.443
1i59ANPChemotaxis protein CheA2.7.13.30.443
1m17AQ4Epidermal growth factor receptor2.7.10.10.443
1phePIYCamphor 5-monooxygenase1.14.15.10.443
1xe55FEPlasmepsin-23.4.23.390.443
1zeoC01Peroxisome proliferator-activated receptor gamma/0.443
1zsf0ZSGag-Pol polyprotein3.4.23.160.443
2c475IDCasein kinase I isoform gamma-2/0.443
2ds11CDCyclin-dependent kinase 22.7.11.220.443
2dteNAIGlucose 1-dehydrogenase related protein/0.443
2gs7ANPEpidermal growth factor receptor2.7.10.10.443
2znoS44Peroxisome proliferator-activated receptor gamma/0.443
3clyACPFibroblast growth factor receptor 2/0.443
3d8bADPFidgetin-like protein 13.6.40.443
3flwFLWMitogen-activated protein kinase 14/0.443
3flzFLZMitogen-activated protein kinase 14/0.443
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.443
3kpkFADSulfide-quinone reductase/0.443
3mjhGTPRas-related protein Rab-5A/0.443
3pj8404Cyclin-dependent kinase 22.7.11.220.443
3vrwYS5Vitamin D3 receptor/0.443
3wowANPCasein kinase II subunit alpha2.7.11.10.443
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.443
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.443
3zonIK1Non-receptor tyrosine-protein kinase TYK22.7.10.20.443
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.443
4jqeANPCasein kinase II subunit alpha2.7.11.10.443
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.443
4nmdFDABifunctional protein PutA/0.443
4utdACPAurora kinase A2.7.11.10.443
1bdlIM1Gag-Pol polyprotein3.4.23.160.442
1l8qADPChromosomal replication initiator protein DnaA/0.442
1oi9N20Cyclin-dependent kinase 22.7.11.220.442
1oiuN76Cyclin-dependent kinase 22.7.11.220.442
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.442
1rfuADPPyridoxal kinase2.7.1.350.442
1sbgIM1Gag-Pol polyprotein/0.442
1u8fNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1yvj4STTyrosine-protein kinase JAK32.7.10.20.442
2fleAIProtease/0.442
2izsBRQCasein kinase I isoform gamma-32.7.11.10.442
2pwcG3GGag-Pol polyprotein3.4.23.160.442
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.442
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3dcrKVSProtease/0.442
3el1DR7Gag-Pol polyprotein3.4.23.160.442
3kb6NADD-lactate dehydrogenase/0.442
3ndtROCGag-Pol polyprotein3.4.23.160.442
3nu6478Gag-Pol polyprotein3.4.23.160.442
3nuo478Gag-Pol polyprotein3.4.23.160.442
3s54017Protease/0.442
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.442
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.442
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.442
4a6cQG9Gag-Pol polyprotein3.4.23.160.442
4b8wNAPGDP-L-fucose synthase1.1.1.2710.442
4cdmFADDeoxyribodipyrimidine photolyase/0.442
4dbzNDPPutative ketoacyl reductase1.3.10.442
4dqh017Gag-Pol polyprotein/0.442
4f081RSTyrosine-protein kinase JAK2/0.442
4f9fGDPPutative glycosyltransferase/0.442
4hnf16WCasein kinase I isoform delta2.7.11.10.442
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.442
4ib4ERM5-hydroxytryptamine receptor 2B/0.442
4kwi1TJReductase homolog/0.442
4ylfFADDihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog/0.442
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.442
1cx4CMPcAMP-dependent protein kinase type II-beta regulatory subunit/0.441
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1mg5NAIAlcohol dehydrogenase1.1.1.10.441
1mp0NADAlcohol dehydrogenase class-31.1.1.10.441
1oguST8Cyclin-dependent kinase 22.7.11.220.441
1ol5ADPAurora kinase A2.7.11.10.441
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.441
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.441
1t7kBH0Gag-Pol polyprotein3.4.23.160.441
2a94AP0L-lactate dehydrogenase1.1.1.270.441
2baqPQBMitogen-activated protein kinase 14/0.441
2ebaFADPutative glutaryl-CoA dehydrogenase/0.441
2j0k4STFocal adhesion kinase 12.7.10.20.441
2ou2ACOHistone acetyltransferase KAT5/0.441
2pmdGNPTranslation initiation factor 2 subunit gamma/0.441
2psuMUUProtease/0.441
2q4bNAPUncharacterized protein At5g02240/0.441
2r3jSCJCyclin-dependent kinase 22.7.11.220.441
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.441
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.441
3cyxROCGag-Pol polyprotein3.4.23.160.441
3ekv478Gag-Pol polyprotein3.4.23.160.441
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.441
3gi4K60Gag-Pol polyprotein/0.441
3gw9VNILanosterol 14-alpha-demethylase/0.441
3hllI45Mitogen-activated protein kinase 14/0.441
3jw2017Gag-Pol polyprotein3.4.23.160.441
3jynNDPQuinone oxidoreductase/0.441
3lfqA28Cyclin-dependent kinase 22.7.11.220.441
3mqe416Prostaglandin G/H synthase 21.14.99.10.441
3s43478Protease/0.441
3syiFADSulfide-quinone reductase/0.441
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.441
4hgs15GCasein kinase I isoform gamma-32.7.11.10.441
4hy6FJ1Heat shock protein HSP 90-alpha/0.441
4kiq1RAMitogen-activated protein kinase 14/0.441
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
4tuvCPZCytochrome P450 1191.140.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
5auwQUEDeath-associated protein kinase 12.7.11.10.441
1d4kPI8Gag-Pol polyprotein3.4.23.160.440
1h1r6CPCyclin-dependent kinase 22.7.11.220.440
1k6cMK1Gag-Pol polyprotein3.4.23.160.440
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.440
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.440
1qbu846Gag-Pol polyprotein3.4.23.160.440
1zsr0ZTGag-Pol polyprotein3.4.23.160.440
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.440
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.440
2i0aMUIProtease/0.440
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.440
2ji8FYNOxalyl-CoA decarboxylase4.1.1.80.440
2of2547Tyrosine-protein kinase Lck2.7.10.20.440
2q5kAB1Protease/0.440
2yxuATPPyridoxal kinase2.7.1.350.440
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.440
3ndxRITGag-Pol polyprotein3.4.23.160.440
3nxxNDPDihydrofolate reductase1.5.1.30.440
3ohh3HHBeta-secretase 13.4.23.460.440
3q9xEMOCasein kinase II subunit alpha2.7.11.10.440
3r4b74TGag-Pol polyprotein/0.440
3s4qNK0Mitogen-activated protein kinase 14/0.440
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4a1zADPKinesin-like protein KIF11/0.440
4djoMK5Pol polyprotein/0.440
4dqc017Gag-Pol polyprotein/0.440
4enhFVXCholesterol 24-hydroxylase/0.440
4eos1ROCyclin-dependent kinase 22.7.11.220.440
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.440
4hbnCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.440
4j95ACPFibroblast growth factor receptor 2/0.440
4jbpYPHAurora kinase A2.7.11.10.440
4kbc1QJCasein kinase I isoform delta2.7.11.10.440
4ktkKTKCytochrome P450/0.440
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440