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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1rt1MKCGag-Pol polyprotein2.7.7.49

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1rt1MKCGag-Pol polyprotein2.7.7.491.000
1c1bGCAGag-Pol polyprotein2.7.7.490.722
3dmjGWEPol protein/0.651
1c1c612Gag-Pol polyprotein2.7.7.490.648
3ffi3OBGag-Pol polyprotein2.7.7.490.635
1rtiHEFGag-Pol polyprotein2.7.7.490.624
3dleGFAGag-Pol polyprotein2.7.7.490.616
3dokGWJPol protein/0.613
1jlaTNKGag-Pol polyprotein2.7.7.490.612
1rt2TNKGag-Pol polyprotein2.7.7.490.608
3dyaPZLGag-Pol polyprotein2.7.7.490.608
3is9AC7Gag-Pol polyprotein2.7.7.490.599
1rt5UC2Gag-Pol polyprotein2.7.7.490.598
3lanKBTGag-Pol polyprotein2.7.7.490.596
3c6tM14Gag-Pol polyprotein2.7.7.490.587
4h4m494Gag-Pol polyprotein2.7.7.490.586
1klmSPPGag-Pol polyprotein2.7.7.490.583
4i7fNVEGag-Pol polyprotein2.7.7.490.583
3lamKRPGag-Pol polyprotein2.7.7.490.582
3c6uM22Gag-Pol polyprotein2.7.7.490.581
3e01PZ2Gag-Pol polyprotein2.7.7.490.581
3t1a5MAGag-Pol polyprotein2.7.7.490.581
4rw6494Gag-Pol polyprotein2.7.7.490.580
1ep4S11Gag-Pol polyprotein2.7.7.490.577
2be2R22Gag-Pol polyprotein2.7.7.490.577
3i0rRT3Gag-Pol polyprotein2.7.7.490.577
4mfb29TGag-Pol polyprotein2.7.7.490.574
3di6PDZGag-Pol polyprotein2.7.7.490.572
1tktH12Gag-Pol polyprotein2.7.7.490.570
4rw4494Gag-Pol polyprotein2.7.7.490.569
2ynhEURGag-Pol polyprotein2.7.7.490.566
2ze2T27Gag-Pol polyprotein2.7.7.490.566
3dolGWIPol protein/0.565
3t195MAGag-Pol polyprotein2.7.7.490.565
4h4o506Gag-Pol polyprotein2.7.7.490.564
3lalKRVGag-Pol polyprotein2.7.7.490.560
3dlgGWEGag-Pol polyprotein2.7.7.490.558
3i0sRT7Gag-Pol polyprotein2.7.7.490.556
3lakKR1Gag-Pol polyprotein2.7.7.490.556
1tvrTB9Gag-Pol polyprotein2.7.7.490.550
3drrR8EGag-Pol polyprotein2.7.7.490.547
1hniAAAGag-Pol polyprotein2.7.7.490.544
2rkiTT1Gag-Pol polyprotein2.7.7.490.544
3tamM06Gag-Pol polyprotein2.7.7.490.543
1revTB9Gag-Pol polyprotein2.7.7.490.542
1tl3H20Gag-Pol polyprotein2.7.7.490.537
1s1vTNKGag-Pol polyprotein2.7.7.490.535
1hpzAAPGag-Pol polyprotein2.7.7.490.532
2ynfWHUGag-Pol polyprotein2.7.7.490.532
2b5j3ACGag-Pol polyprotein2.7.7.490.531
3nbpJGZGag-Pol polyprotein2.7.7.490.525
1hquHBYGag-Pol polyprotein2.7.7.490.524
4i2q1BTGag-Pol polyprotein2.7.7.490.521
1tkzH16Gag-Pol polyprotein2.7.7.490.517
2wonZZEGag-Pol polyprotein2.7.7.490.515
3drpR8EGag-Pol polyprotein2.7.7.490.514
4kko1REGag-Pol polyprotein2.7.7.490.514
1s9eADBGag-Pol polyprotein2.7.7.490.510
4ko0JLJGag-Pol polyprotein2.7.7.490.508
1s6qTPBGag-Pol polyprotein2.7.7.490.505
1eetBFUGag-Pol polyprotein2.7.7.490.504
3m8qDJZGag-Pol polyprotein2.7.7.490.503
5cyqT27Gag-Pol polyprotein2.7.7.490.503
1hnvTBOGag-Pol polyprotein2.7.7.490.501
1s1tUC1Gag-Pol polyprotein2.7.7.490.501
4ifvT27Gag-Pol polyprotein2.7.7.490.500
2ic3HBYGag-Pol polyprotein2.7.7.490.492
4xldBRLPeroxisome proliferator-activated receptor gamma/0.492
3rfmCFFAdenosine receptor A2a/0.492
4wa9AXITyrosine-protein kinase ABL12.7.10.20.490
3uzcT4EAdenosine receptor A2a/0.490
2jleI15Reverse transcriptase/RNaseH/0.489
5iua6DXAdenosine receptor A2a/0.489
3t8xT8XT-cell surface glycoprotein CD1b/0.488
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.488
2oprHBQGag-Pol polyprotein2.7.7.490.484
3inwJZBHeat shock protein HSP 90-alpha/0.484
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.484
4b14NHWGlycylpeptide N-tetradecanoyltransferase/0.484
2vg7NNIGag-Pol polyprotein2.7.7.490.483
6coxS58Prostaglandin G/H synthase 21.14.99.10.483
2opqHBQGag-Pol polyprotein2.7.7.490.480
4z9g1Q5Corticotropin-releasing factor receptor 1/0.479
1cx2S58Prostaglandin G/H synthase 21.14.99.10.478
1tkxGWBGag-Pol polyprotein2.7.7.490.478
1xddAAYIntegrin alpha-L/0.478
4i8vBHFCytochrome P450 1A11.14.14.10.477
3nx4NAPPutative oxidoreductase/0.476
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.476
3sn6P0GBeta-2 adrenergic receptor/0.476
1m79MQ1Dihydrofolate reductase1.5.1.30.475
2vd0D27Hematopoietic prostaglandin D synthase/0.475
1aq1STUCyclin-dependent kinase 22.7.11.220.474
2hj3FADFAD-linked sulfhydryl oxidase ERV1/0.474
3p6mDSOCamphor 5-monooxygenase1.14.15.10.474
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.473
2oppHBQGag-Pol polyprotein2.7.7.490.472
4b12NHWGlycylpeptide N-tetradecanoyltransferase/0.472
4mv1ADPBiotin carboxylase6.3.4.140.472
3emlZMAAdenosine receptor A2a/0.472
2p4yC03Peroxisome proliferator-activated receptor gamma/0.471
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.471
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.471
4qa0SHHHistone deacetylase 83.5.1.980.471
5k2cZMAAdenosine receptor A2a/0.471
1ikvEFZGag-Pol polyprotein2.7.7.490.470
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.470
2vn0TDZCytochrome P450 2C8/0.470
3tk3CPZCytochrome P450 2B41.14.14.10.469
3uzaT4GAdenosine receptor A2a/0.469
1uy8PU5Heat shock protein HSP 90-alpha/0.468
2ath3EAPeroxisome proliferator-activated receptor gamma/0.468
4a4wYFBPeroxisome proliferator-activated receptor gamma/0.468
1rt7UC4Gag-Pol polyprotein2.7.7.490.467
2npaMMBPeroxisome proliferator-activated receptor alpha/0.467
3cd2MTXDihydrofolate reductase1.5.1.30.467
5k2dZMAAdenosine receptor A2a/0.467
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
3inxJZCHeat shock protein HSP 90-alpha/0.466
4iaq2GM5-hydroxytryptamine receptor 1B/0.466
2yneNHWGlycylpeptide N-tetradecanoyltransferase/0.465
3a0iAJIGlucokinase2.7.1.20.465
3dl9V2HVitamin D 25-hydroxylase/0.465
3opdHIEHeat shock protein 83/0.465
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.465
4ejh0QACytochrome P450 2A131.14.14.10.465
1fkoEFZGag-Pol polyprotein2.7.7.490.464
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.464
3irxUDRGag-Pol polyprotein2.7.7.490.463
4b13NHWGlycylpeptide N-tetradecanoyltransferase/0.463
5iu86DZAdenosine receptor A2a/0.463
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.462
2ovhAS0Progesterone receptor/0.462
3bjhNBBOdorant binding protein ASP1/0.462
3p9tTCLRepressor/0.462
1vrwNAIEnoyl-ACP reductase/0.461
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.460
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.460
4zasTYDCalS13/0.460
2hamC33Vitamin D3 receptor/0.459
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3jzfJZKBiotin carboxylase6.3.4.140.459
3t2yFADSulfide-quinone reductase/0.459
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.459
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.458
2ibzSMACytochrome b/0.458
2pl0STITyrosine-protein kinase Lck2.7.10.20.458
2q5p241Peroxisome proliferator-activated receptor gamma/0.458
2znq401Peroxisome proliferator-activated receptor delta/0.458
3qlhT27Gag-Pol polyprotein2.7.7.490.458
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
1lwlDSOCamphor 5-monooxygenase1.14.15.10.457
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.457
1w87NAPFerredoxin--NADP reductase1.18.1.20.457
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.457
2rf2MRXGag-Pol polyprotein2.7.7.490.457
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
5ag5MYAGlycylpeptide N-tetradecanoyltransferase/0.457
1tl7FOKAdenylate cyclase type 2/0.456
1tl7FOKAdenylate cyclase type 5/0.456
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.456
3cx5SMACytochrome b/0.456
3njoPYVAbscisic acid receptor PYR1/0.456
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.456
4iae1DXAlr2278 protein/0.456
4iah1DXAlr2278 protein/0.456
3vvpBNUUncharacterized protein/0.455
4b10NHWGlycylpeptide N-tetradecanoyltransferase/0.455
4j6bPLOCytochrome P450 monooxygenase/0.455
1fk9EFZGag-Pol polyprotein2.7.7.490.454
1rdtL79Retinoic acid receptor RXR-alpha/0.454
2zb8IMNProstaglandin reductase 21.3.1.480.454
3uxe465Ribosyldihydronicotinamide dehydrogenase [quinone]/0.454
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.454
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.454
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.453
1uykPUXHeat shock protein HSP 90-alpha/0.453
1zeoC01Peroxisome proliferator-activated receptor gamma/0.453
2dvlFADAcyl-CoA dehydrogenase/0.453
2hnzPC0Gag-Pol polyprotein2.7.7.490.453
2jn3JN3Fatty acid-binding protein, liver/0.453
3t14FADSulfide-quinone reductase/0.453
3vev0H4Glucokinase2.7.1.20.453
4a2zMYAGlycylpeptide N-tetradecanoyltransferase/0.453
4bfwZVWPantothenate kinase2.7.1.330.453
4j6dTESCytochrome P450 monooxygenase/0.453
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.453
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.453
1errRALEstrogen receptor/0.452
1k74544Peroxisome proliferator-activated receptor gamma/0.452
1uydPU8Heat shock protein HSP 90-alpha/0.452
1wsvTHHAminomethyltransferase, mitochondrial/0.452
2hc4VDXVitamin D3 receptor A/0.452
3a783EVVitamin D3 receptor/0.452
3vspEK8Peroxisome proliferator-activated receptor gamma/0.452
4apuA2KProgesterone receptor/0.452
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.452
4iarERM5-hydroxytryptamine receptor 1B/0.452
4jlj1NMDeoxycytidine kinase2.7.1.740.452
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.452
1m7aMQUDihydrofolate reductase1.5.1.30.451
2q8sL92Peroxisome proliferator-activated receptor gamma/0.451
3u8hBHPPhospholipase A2, membrane associated/0.451
4awq592Heat shock protein HSP 90-alpha/0.451
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.451
4jvmXDIEstrogen sulfotransferase2.8.2.40.451
4kgmATPUncharacterized protein/0.451
4mleVO1Glucokinase2.7.1.20.451
4mzuTYDWxcM-like protein/0.451
5kf1ACOPredicted acetyltransferase/0.451
3reyXACAdenosine receptor A2a/0.451
1kkq471Peroxisome proliferator-activated receptor alpha/0.450
1pkfEPDEpothilone C/D epoxidase1.140.450
1uy6PU3Heat shock protein HSP 90-alpha/0.450
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.450
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.450
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.450
3ijdC2FMethylenetetrahydrofolate reductase/0.450
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.450
4b2gV1NUncharacterized protein/0.450
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.450
5ag7MYAGlycylpeptide N-tetradecanoyltransferase/0.450
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.450
1cqp803Integrin alpha-L/0.449
1rdt570Peroxisome proliferator-activated receptor gamma/0.449
1xu7CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
4ead0NPThymidine phosphorylase2.4.2.40.449
4jvlESTEstrogen sulfotransferase2.8.2.40.449
4l0qNADAlcohol dehydrogenase class-3/0.449
5iu4ZMAAdenosine receptor A2a/0.449
1ia2TQ4Dihydrofolate reductase1.5.1.30.448
1kb9SMACytochrome b/0.448
1ndeMONEstrogen receptor beta/0.448
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2gtk208Peroxisome proliferator-activated receptor gamma/0.448
2qe4JJ3Estrogen receptor/0.448
2zl9VDAVitamin D3 receptor/0.448
3d0bSNXHeat shock protein HSP 90-alpha/0.448
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
4eos1ROCyclin-dependent kinase 22.7.11.220.448
4ib4ERM5-hydroxytryptamine receptor 2B/0.448
4j6cSTRCytochrome P450 monooxygenase/0.448
4ubsDIFPentalenic acid synthase1.14.15.110.448
4uymVOR14-alpha sterol demethylase Cyp51B/0.448
1ikxPNUGag-Pol polyprotein2.7.7.490.447
2dubCO8Enoyl-CoA hydratase, mitochondrial4.2.1.170.447
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.447
2pobGW4Peroxisome proliferator-activated receptor gamma/0.447
2yiuSMACytochrome b/0.447
3b6zCO7Enoyl reductase LovC10.447
3sf6FDAGlutaryl-CoA dehydrogenase/0.447
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.447
3td8D2RDihydrofolate reductase1.5.1.30.447
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.447
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.447
4bfuZVUPantothenate kinase2.7.1.330.447
4lsl1YQGag-Pol polyprotein2.7.7.490.447
4nh82LCHeat shock protein HSP 90-alpha/0.447
4o1mNADEnoyl-acyl carrier reductase/0.447
4qa1B3NHistone deacetylase 83.5.1.980.447
1ie9VDXVitamin D3 receptor/0.446
1rkhVD2Vitamin D3 receptor/0.446
2ardFDAFlavin-dependent tryptophan halogenase PrnA1.14.19.90.446
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
3dds26BGlycogen phosphorylase, liver form2.4.1.10.446
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.446
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
4bkjSTIEpithelial discoidin domain-containing receptor 12.7.10.10.446
4cgpMYAGlycylpeptide N-tetradecanoyltransferase/0.446
4ixfIXFDihydrofolate reductase1.5.1.30.446
4qa2SHHHistone deacetylase 83.5.1.980.446
1dnaCB3Thymidylate synthase/0.445
1fm9570Peroxisome proliferator-activated receptor gamma/0.445
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.445
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.445
2pirDHTAndrogen receptor/0.445
2w98P1ZProstaglandin reductase 21.3.1.480.445
3ce31FNHepatocyte growth factor receptor2.7.10.10.445
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.445
4nx7FOLDihydrofolate reductase1.5.1.30.445
4r20AERCytochrome P450 family 17 polypeptide 2/0.445
1hvyD16Thymidylate synthase2.1.1.450.444
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.444
1xzqFONtRNA modification GTPase MnmE3.6.50.444
2bbqPFGThymidylate synthase/0.444
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.444
3fnu006HAP protein/0.444
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.444
3mnrSD1Heat shock protein HSP 90-alpha/0.444
3vg9ZMAAdenosine receptor A2a/0.444
3zc3NAPFerredoxin--NADP reductase1.18.1.20.444
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.444
4c2xNHWGlycylpeptide N-tetradecanoyltransferase 2/0.444
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.444
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.444
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4o761M3Bromodomain-containing protein 4/0.444
5dc5B3NHistone deacetylase 83.5.1.980.444
1ai9NDPDihydrofolate reductase1.5.1.30.443
1e1nFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.443
1ezvSMACytochrome b/0.443
1ia4TQ6Dihydrofolate reductase1.5.1.30.443
1iyzNDPProbable quinone oxidoreductase/0.443
1kt6RTLRetinol-binding protein 4/0.443
1pq6965Oxysterols receptor LXR-beta/0.443
1s19MC9Vitamin D3 receptor/0.443
1uomPTIEstrogen receptor/0.443
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.443
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2atiIHUGlycogen phosphorylase, liver form2.4.1.10.443
2q59240Peroxisome proliferator-activated receptor gamma/0.443
2qpyDHTAndrogen receptor/0.443
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.443
3a1l2CCCytochrome P450/0.443
3a60STURibosomal protein S6 kinase beta-12.7.11.10.443
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.443
3kk6CELProstaglandin G/H synthase 11.14.99.10.443
3l6jZ90Alr2278 protein/0.443
3maaFKPAdenylate cyclase type 2/0.443
3maaFKPAdenylate cyclase type 5/0.443
3nj0PYVAbscisic acid receptor PYL2/0.443
4cnjFADL-amino acid oxidase/0.443
4iq71G9Mycocyclosin synthase1.14.21.90.443
4jvnYUGEstrogen sulfotransferase2.8.2.40.443
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
4xqcNADHomospermidine synthase2.5.1.440.443
1dggNDPCatalase1.11.1.60.442
1fmjRTLRetinol dehydratase/0.442
1fvt106Cyclin-dependent kinase 22.7.11.220.442
1jlqSBNGag-Pol polyprotein2.7.7.490.442
1p93DEXGlucocorticoid receptor/0.442
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
1vruAAPGag-Pol polyprotein2.7.7.490.442
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2fwyH64Heat shock protein HSP 90-alpha/0.442
2h55DZ8Heat shock protein HSP 90-alpha/0.442
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.442
2jedLG8Protein kinase C theta type2.7.11.130.442
2vnhFADNADPH:ferredoxin reductase/0.442
3abaFLICytochrome P450/0.442
3e5aVX6Aurora kinase A2.7.11.10.442
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3le62BZCyclin-dependent kinase 22.7.11.220.442
3mtfA3FActivin receptor type-12.7.11.300.442
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.442
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.442
3srwQ27Dihydrofolate reductase1.5.1.30.442
3v94WYQPhosphodiesterase/0.442
4cd2FOLDihydrofolate reductase1.5.1.30.442
4fhi0S4Vitamin D3 receptor A/0.442
4xwtU5PRibonuclease J/0.442
4z35ON9Lysophosphatidic acid receptor 1/0.442
1cjkFOKAdenylate cyclase type 2/0.441
1cjkFOKAdenylate cyclase type 5/0.441
1f28F89Thymidylate synthase2.1.1.450.441
1jx0DFVChalcone--flavonone isomerase 15.5.1.60.441
1s0zEB1Vitamin D3 receptor/0.441
1ykdCMPAdenylate cyclase/0.441
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.441
2d29FADAcyl-CoA dehydrogenase/0.441
2hw2RFPRifampin ADP-ribosyl transferase/0.441
2p1v5TNRetinoic acid receptor RXR-alpha/0.441
3g6zA7TRenin3.4.23.150.441
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
3pqbVGPPutative oxidoreductase/0.441
3qlzQLZUncharacterized protein/0.441
3r7cFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.441
4bfvZVVPantothenate kinase2.7.1.330.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4hni16WCasein kinase I isoform epsilon2.7.11.10.441
4ig01FGGag-Pol polyprotein2.7.7.490.441
4jbtASDCytochrome P450 monooxygenase/0.441
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.441
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.441
5ahkTPPAcetolactate synthase II, large subunit/0.441
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.441
5uviZMAAdenosine receptor A2a/0.441
1dgbNDPCatalase1.11.1.60.440
1eioGCHGastrotropin/0.440
1ek2CDUBifunctional epoxide hydrolase 2/0.440
1jtqLY3Thymidylate synthase/0.440
1og5SWFCytochrome P450 2C9/0.440
2cig1DGDihydrofolate reductase1.5.1.30.440
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2wesFADTryptophan 5-halogenase/0.440
2ykeYKEHeat shock protein HSP 90-alpha/0.440
3be9P04Casein kinase II subunit alpha2.7.11.10.440
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.440
3kpkFADSulfide-quinone reductase/0.440
3mqe416Prostaglandin G/H synthase 21.14.99.10.440
3nwlNDPCatalase1.11.1.60.440
3vt7VDXVitamin D3 receptor/0.440
4b8zNAPGDP-L-fucose synthase1.1.1.2710.440
4coxIMNProstaglandin G/H synthase 21.14.99.10.440
4g1d0VKVitamin D3 receptor A/0.440
4jvr1MTE3 ubiquitin-protein ligase Mdm26.3.20.440
4r21STRCytochrome P450 family 17 polypeptide 2/0.440
4y7cNAPNADPH--cytochrome P450 reductase/0.440
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.440
5e8ySTUTGF-beta receptor type-22.7.11.300.440
5eccNAPDehydrofolate reductase type I/0.440