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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ri4SAMmRNA cap guanine-N7 methyltransferase2.1.1.56

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ri4SAMmRNA cap guanine-N7 methyltransferase2.1.1.561.000
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.574
1ri3SAHmRNA cap guanine-N7 methyltransferase2.1.1.560.486
1z3cSA8mRNA cap guanine-N7 methyltransferase2.1.1.560.484
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.482
2zsaADPPantothenate kinase2.7.1.330.478
4m83ERYOleandomycin glycosyltransferase2.4.10.466
2iyfERYOleandomycin glycosyltransferase2.4.10.465
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.463
2g8yNADHydroxycarboxylate dehydrogenase B/0.455
3aezGDPPantothenate kinase2.7.1.330.452
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.451
2gesCOKPantothenate kinase2.7.1.330.451
5e9wSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.451
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.450
1np7FADCryptochrome DASH/0.449
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.447
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.446
1xe55FEPlasmepsin-23.4.23.390.443
2wb2FADRE11660p/0.440
4i1iNADMalate dehydrogenase/0.440
4yxm2BADNA integrity scanning protein DisA/0.440