scPDB - Distribution of Binding site Similarity values of 1re7 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1re7	FOL	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1re7	FOL	Dihydrofolate reductase	1.5.1.3	1.000
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.629
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.614
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.587
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.584
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.578
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.565
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.564
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.564
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.563
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.554
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.551
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.551
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.550
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.550
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.541
5hi6	MTX	Dihydrofolate reductase	/	0.537
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.535
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.534
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.530
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.529
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.528
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.527
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.524
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.517
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	0.509
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.509
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.505
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.488
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.487
4x5f	FOL	Dihydrofolate reductase	1.5.1.3	0.473
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.465
4ele	31I	Dihydrofolate reductase	/	0.460
1jom	FFO	Dihydrofolate reductase	1.5.1.3	0.459
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.457
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.455
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.455
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.454
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.450
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.450
1rx5	DDF	Dihydrofolate reductase	1.5.1.3	0.449
4elb	34S	Dihydrofolate reductase	/	0.449
3fl8	RAR	Dihydrofolate reductase	/	0.445
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.444
4elg	52J	Dihydrofolate reductase	/	0.441
4x5h	FOL	Dihydrofolate reductase	1.5.1.3	0.441