scPDB - Distribution of Binding site Similarity values of 1ra3 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1ra3	MTX	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1ra3	MTX	Dihydrofolate reductase	1.5.1.3	1.000
1ra8	FOL	Dihydrofolate reductase	1.5.1.3	0.661
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.627
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.618
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.613
5hi6	MTX	Dihydrofolate reductase	/	0.600
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.595
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.595
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.591
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.587
1dyh	DZF	Dihydrofolate reductase	1.5.1.3	0.581
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.577
4x5h	FOL	Dihydrofolate reductase	1.5.1.3	0.575
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.574
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.567
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.566
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.562
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.559
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.559
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.552
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.549
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.542
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.539
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.533
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.530
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.518
2cig	1DG	Dihydrofolate reductase	1.5.1.3	0.516
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.498
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.485
1rx5	DDF	Dihydrofolate reductase	1.5.1.3	0.479
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.479
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.469
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.466
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.465
1u71	MXA	Dihydrofolate reductase	1.5.1.3	0.465
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.461
4qi9	MTX	Dihydrofolate reductase	/	0.461
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.460
3f03	FMN	Pentaerythritol tetranitrate reductase	/	0.454
3hl0	NAD	Maleylacetate reductase	/	0.454
1ia4	TQ6	Dihydrofolate reductase	1.5.1.3	0.451
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.451
3tqa	NDP	Dihydrofolate reductase	/	0.450
4kne	1CY	Dihydrofolate reductase	1.5.1.3	0.450
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.449
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.444
4ipw	1G7	Mycocyclosin synthase	1.14.21.9	0.444
1dr3	TAP	Dihydrofolate reductase	1.5.1.3	0.443
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.443
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.443
1ia1	NDP	Dihydrofolate reductase	1.5.1.3	0.442
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.441
3kjs	NAP	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.440
3uag	UMA	UDP-N-acetylmuramoylalanine--D-glutamate ligase	6.3.2.9	0.440