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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1qvtPRLHTH-type transcriptional regulator QacR

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1qvtPRLHTH-type transcriptional regulator QacR/1.000
1jt6DEQHTH-type transcriptional regulator QacR/0.610
1qvuPRLHTH-type transcriptional regulator QacR/0.569
3bt9DEQHTH-type transcriptional regulator QacR/0.542
1rpwDIDHTH-type transcriptional regulator QacR/0.524
3br2DEQHTH-type transcriptional regulator QacR/0.521
1rkwPNTHTH-type transcriptional regulator QacR/0.455
1jumBERHTH-type transcriptional regulator QacR/0.450
3btjDEQHTH-type transcriptional regulator QacR/0.450