sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1qsm | ACO | Histone acetyltransferase HPA2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 1.000 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.486 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.483 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.481 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.480 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.466 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.465 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.465 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.464 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.462 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.460 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.457 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.456 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.456 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.454 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.453 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.452 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.452 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.448 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.445 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.442 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.442 |