scPDB - Distribution of Binding site Similarity values of 1q8w entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1q8w	M77	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1q8w	M77	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	1.000
2uzv	SS5	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.598
1ydt	IQB	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.595
2vo0	M03	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.590
2oh0	2PY	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.583
1q8u	H52	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.572
2uzu	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.564
3zo1	SIJ	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.563
2uzw	SS4	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.558
1veb	I05	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.550
1ydr	IQP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.544
2uw0	GVK	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.539
3zo4	QWI	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.539
2f7e	2EA	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.538
2vo7	M05	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.538
2uw6	GVO	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.536
2f7z	6EA	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.535
2jdt	I5S	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.535
2vo3	M04	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.533
2gu8	796	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.532
2ojf	4PY	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.530
2vo6	M05	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.530
3vqh	IQB	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.530
3bwj	ARX	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.527
1q8t	Y27	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.525
2c1a	I5S	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.524
2uvz	GVJ	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.523
3ow3	SMY	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.519
4gv1	0XZ	RAC-alpha serine/threonine-protein kinase	2.7.11.1	0.519
4c34	STU	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.518
2gnf	Y27	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.517
1bx6	BA1	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.516
3kkv	B99	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.516
2uw7	GVP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.515
4axa	RKD	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.515
2uzt	SS3	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.512
3dnd	LL2	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.512
3e8e	G98	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.512
2vnw	M01	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.511
1sve	I01	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.510
1xh6	R94	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.510
2uw4	L15	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.508
4yxs	EMU	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.506
2uw5	GVN	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.505
2gnl	H52	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.504
2jds	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.502
1xh8	R55	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.498
4wbb	ADP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.495
1svh	I08	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.488
3agl	A03	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.486
3e8c	G96	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.486
4l43	5FI	Ribosomal protein S6 kinase beta-1	2.7.11.1	0.486
4ekl	0RF	RAC-alpha serine/threonine-protein kinase	2.7.11.1	0.485
3dne	LL1	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.483
4fti	H7K	Serine/threonine-protein kinase Chk1	2.7.11.1	0.476
1rej	B1L	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.475
3mvh	WFE	RAC-alpha serine/threonine-protein kinase	2.7.11.1	0.475
3a62	STU	Ribosomal protein S6 kinase beta-1	2.7.11.1	0.474
1xh5	R68	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.473
4oti	MI1	Serine/threonine-protein kinase N1	/	0.473
2f2u	M77	Rho-associated protein kinase 2	2.7.11.1	0.472
1xha	R68	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.471
2c1b	CQP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.470
3l9m	L9M	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.467
3nyn	SGV	G protein-coupled receptor kinase 6	2.7.11.16	0.466
1xh9	R69	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.465
3v5w	8PR	Beta-adrenergic receptor kinase 1	2.7.11.15	0.465
2etr	Y27	Rho-associated protein kinase 1	2.7.11.1	0.462
3l9l	L9L	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.462
3l9n	L9N	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.461
4jik	1KO	Serine/threonine-protein kinase Chk1	2.7.11.1	0.458
1zth	ADP	RIO-type serine/threonine-protein kinase Rio1	2.7.11.1	0.457
2f7x	4EA	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.457
2j0l	ANP	Focal adhesion kinase 1	2.7.10.2	0.457
3oog	YTP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.457
2gnh	H52	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.455
2cke	IQU	Death-associated protein kinase 2	/	0.454
4enx	Z20	Serine/threonine-protein kinase pim-1	2.7.11.1	0.452
1svg	I04	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.451
1xr1	ANP	Serine/threonine-protein kinase pim-1	2.7.11.1	0.451
2jdv	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.451
1ny3	ADP	MAP kinase-activated protein kinase 2	2.7.11.1	0.448
1stc	STU	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.448
4iay	ADP	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.447
5av2	KMP	Death-associated protein kinase 1	2.7.11.1	0.447
4nif	ANP	Mitogen-activated protein kinase 1	2.7.11.24	0.446
4fv1	EK4	Mitogen-activated protein kinase 1	2.7.11.24	0.445
1xh4	R69	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.442
2uzb	C75	Cyclin-dependent kinase 2	2.7.11.22	0.441