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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.628
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.620
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.620
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.618
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.616
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.607
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.591
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.577
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.577
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.567
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.547
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.546
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.546
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.544
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.521
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.476
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.471
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.451
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.446
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3i60E86Mitogen-activated protein kinase 12.7.11.240.445
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440