sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1q4x | G24 | Thyroid hormone receptor beta |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1q4x | G24 | Thyroid hormone receptor beta | / | 1.000 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.596 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.523 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.522 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.514 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.494 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.492 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.491 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.491 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.490 | |
| 3d57 | 4HY | Thyroid hormone receptor beta | / | 0.488 | |
| 1nax | IH5 | Thyroid hormone receptor beta | / | 0.487 | |
| 1fml | RTL | Retinol dehydratase | / | 0.486 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.486 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.486 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.486 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.483 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.481 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 1n46 | PFA | Thyroid hormone receptor beta | / | 0.479 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.478 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.478 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.477 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.477 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.476 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.476 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.476 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.475 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.475 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.475 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.475 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.474 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.474 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.473 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.473 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.472 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.472 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.471 | |
| 2j4a | OEF | Thyroid hormone receptor beta | / | 0.470 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.470 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.470 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.470 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 2pin | 4HY | Thyroid hormone receptor beta | / | 0.469 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.468 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.467 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.467 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.467 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.466 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.466 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.466 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.466 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 3up0 | D7S | aceDAF-12 | / | 0.465 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.465 | |
| 1osv | CHC | Bile acid receptor | / | 0.464 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.464 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.464 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.464 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.464 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.463 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.463 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.463 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.463 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.463 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.463 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.463 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.463 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.462 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.462 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.462 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.461 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.461 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 3up3 | XCA | aceDAF-12 | / | 0.461 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.461 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.461 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.461 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.460 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.460 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.460 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.460 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.460 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.459 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.459 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.459 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.459 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.459 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.459 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.459 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.459 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.459 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.459 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.458 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.458 | |
| 4l04 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.458 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.457 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.457 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.457 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.457 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.456 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.456 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.456 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1jut | LYD | Thymidylate synthase | / | 0.455 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.455 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.455 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.455 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.455 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.455 | |
| 4l9k | EHF | Serum albumin | / | 0.455 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.455 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.454 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.454 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 2x7f | 824 | TRAF2 and NCK-interacting protein kinase | 2.7.11.1 | 0.454 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.454 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.454 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.453 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.453 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.452 | |
| 1ppj | ANY | Cytochrome b | / | 0.452 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.452 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1ysx | 4EB | Serum albumin | / | 0.452 | |
| 2bx8 | AZQ | Serum albumin | / | 0.452 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.452 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.452 | |
| 3p9t | TCL | Repressor | / | 0.452 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.452 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.452 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.452 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.452 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.452 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.452 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.451 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.451 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.451 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.450 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.450 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.450 | |
| 1nav | IH5 | Thyroid hormone receptor alpha | / | 0.450 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.450 | |
| 3ldf | SAH | Uncharacterized protein | / | 0.450 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.450 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.450 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.450 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.450 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.450 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.450 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.449 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.449 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.449 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4b1f | KRH | Glutamate racemase | / | 0.449 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.449 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.449 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.449 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.449 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.448 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.448 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.448 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.448 | |
| 3bej | MUF | Bile acid receptor | / | 0.448 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.448 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.448 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.448 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.448 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.448 | |
| 4xwt | U5P | Ribonuclease J | / | 0.448 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.447 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 3sh0 | SAX | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 3zsi | 52P | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.447 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.447 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.447 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.447 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.446 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.446 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.446 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.446 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.446 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.446 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.446 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.446 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.445 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.445 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.445 | |
| 2nxe | SAM | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.445 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.445 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.445 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.445 | |
| 3tlj | SAH | Uncharacterized protein | / | 0.445 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.445 | |
| 3w0s | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.445 | |
| 4nr4 | 2LK | CREB-binding protein | / | 0.445 | |
| 4rrf | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.445 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.444 | |
| 1ee0 | CAA | 2-pyrone synthase | / | 0.444 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1t0l | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.444 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.444 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.444 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.444 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.444 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.444 | |
| 3kdu | NKS | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.444 | |
| 3vf2 | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.444 | |
| 3vhm | NPK | Avidin | / | 0.444 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 1mb9 | ATP | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.443 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.443 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.443 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.443 | |
| 2e1t | MLC | Anthocyanin malonyltransferase homolog | / | 0.443 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.443 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.443 | |
| 4i3w | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.443 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.443 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.443 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.442 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3h1j | SMA | Cytochrome b | / | 0.442 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.442 | |
| 3pd3 | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.442 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 4b10 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.442 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.442 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.442 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 1dgg | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1mab | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.441 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.441 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.441 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3cx5 | SMA | Cytochrome b | / | 0.441 | |
| 3f5p | 741 | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.441 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.441 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4mfq | COA | Uncharacterized protein | / | 0.441 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1kyo | SMA | Cytochrome b | / | 0.440 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.440 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.440 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.440 | |
| 2wle | COA | Polysialic acid O-acetyltransferase | / | 0.440 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.440 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.440 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.440 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.440 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.440 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4mzu | COA | WxcM-like protein | / | 0.440 | |
| 4qms | 1N1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.440 | |
| 5br4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.440 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.440 |