sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 1.000 | |
| 1pvd | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.552 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.526 | |
| 2w93 | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.519 | |
| 1qpb | TPP | Pyruvate decarboxylase isozyme 1 | / | 0.514 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.470 | |
| 4cok | TPP | Pyruvate decarboxylase | / | 0.468 | |
| 3oe1 | TDL | Pyruvate decarboxylase | 4.1.1.1 | 0.463 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.461 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.460 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.459 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.456 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.447 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.447 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.444 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.443 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 4l04 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.441 | |
| 1w2x | RCP | Acetyl-CoA carboxylase | / | 0.440 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4l06 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 |