sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 1.000 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.517 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.508 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.494 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.478 | |
| 2cdc | NAP | Glucose 1-dehydrogenase | / | 0.475 | |
| 2vwp | NDP | Glucose 1-dehydrogenase | / | 0.472 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.471 | |
| 2b5v | NAP | Glucose 1-dehydrogenase | / | 0.467 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 1pl6 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.465 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.461 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.455 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.454 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.450 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.449 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.447 | |
| 2wpw | ACO | Orf14 | / | 0.446 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.445 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.442 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.440 |