Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1pj2NAINAD-dependent malic enzyme, mitochondrial1.1.1.38

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1pj2NAINAD-dependent malic enzyme, mitochondrial1.1.1.381.000
1pj3NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.784
1efkNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.753
1eflNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.730
1do8NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.625
1gq2NAPNADP-dependent malic enzyme1.1.1.400.543
1pj4ATPNAD-dependent malic enzyme, mitochondrial1.1.1.380.543
1gz4ATPNAD-dependent malic enzyme, mitochondrial1.1.1.380.535
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.453
1nqaNADGlyceraldehyde-3-phosphate dehydrogenase/0.451
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.450
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.442
1rwbNADGlucose 1-dehydrogenase1.1.1.470.440
4j7xNAPSepiapterin reductase1.1.1.1530.440
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.440