sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.795 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.740 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.721 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.715 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.700 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.695 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.636 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.608 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.603 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.601 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.600 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.587 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.582 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.582 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.581 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.579 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.579 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.579 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.575 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.575 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.574 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.573 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.571 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.571 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.568 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.566 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.563 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.563 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.563 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.562 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.562 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.561 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.559 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.556 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.550 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.550 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.549 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.548 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.547 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.541 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.539 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.538 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.536 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.532 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.531 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.529 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.527 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.525 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.524 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.523 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.522 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.519 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.518 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.516 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.516 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.511 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.503 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.503 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.489 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.487 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.483 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.483 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.475 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.475 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.472 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.471 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.467 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.466 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.465 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.461 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.460 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.457 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.456 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.449 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.448 | |
| 4k9v | 6AW | Cytochrome P450 3A4 | / | 0.445 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.442 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 |