sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1p93 | DEX | Glucocorticoid receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1p93 | DEX | Glucocorticoid receptor | / | 1.000 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.597 | |
| 4udc | DEX | Glucocorticoid receptor | / | 0.588 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.569 | |
| 1m2z | DEX | Glucocorticoid receptor | / | 0.565 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.564 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.558 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.557 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.548 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.542 | |
| 3mno | DEX | Glucocorticoid receptor | / | 0.538 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.526 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.525 | |
| 3zrb | ORC | Progesterone receptor | / | 0.517 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.517 | |
| 2w8y | NDR | Progesterone receptor | / | 0.516 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.514 | |
| 1sqn | NDR | Progesterone receptor | / | 0.513 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.511 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.510 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.509 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.509 | |
| 1zuc | T98 | Progesterone receptor | / | 0.507 | |
| 2w8y | 486 | Progesterone receptor | / | 0.507 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.505 | |
| 2ab2 | SNL | Mineralocorticoid receptor | / | 0.503 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 2aa6 | STR | Mineralocorticoid receptor | / | 0.497 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.497 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.493 | |
| 3d90 | NOG | Progesterone receptor | / | 0.492 | |
| 3zrb | OR8 | Progesterone receptor | / | 0.492 | |
| 4apu | A2K | Progesterone receptor | / | 0.492 | |
| 2q7l | TES | Androgen receptor | / | 0.491 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.491 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.489 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.488 | |
| 2pix | DHT | Androgen receptor | / | 0.488 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.487 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.487 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.486 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.485 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 4apu | OR8 | Progesterone receptor | / | 0.483 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.482 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1e3k | R18 | Progesterone receptor | / | 0.480 | |
| 2pio | DHT | Androgen receptor | / | 0.480 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.478 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.478 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.478 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 3zqt | TES | Androgen receptor | / | 0.476 | |
| 3zra | ORB | Progesterone receptor | / | 0.476 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.475 | |
| 4k7a | DHT | Androgen receptor | / | 0.475 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.475 | |
| 2piw | DHT | Androgen receptor | / | 0.474 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.474 | |
| 4oea | DHT | Androgen receptor | / | 0.474 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 3qts | X46 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1eio | GCH | Gastrotropin | / | 0.472 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.472 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.472 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.471 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.471 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.470 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 2ylp | TES | Androgen receptor | / | 0.469 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.469 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.468 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 3erd | DES | Estrogen receptor | / | 0.468 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 2qpy | DHT | Androgen receptor | / | 0.467 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.467 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.467 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.466 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.466 | |
| 1t5z | DHT | Androgen receptor | / | 0.465 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.465 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2aa7 | 1CA | Mineralocorticoid receptor | / | 0.464 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2piu | DHT | Androgen receptor | / | 0.464 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.464 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.463 | |
| 1xj7 | DHT | Androgen receptor | / | 0.463 | |
| 1xq3 | R18 | Androgen receptor | / | 0.463 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.463 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.463 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.463 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 2iog | IOG | Estrogen receptor | / | 0.462 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.462 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.462 | |
| 3v49 | PK0 | Androgen receptor | / | 0.462 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.462 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.461 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.461 | |
| 1fml | RTL | Retinol dehydratase | / | 0.461 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2am9 | TES | Androgen receptor | / | 0.461 | |
| 2ama | DHT | Androgen receptor | / | 0.461 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.461 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.461 | |
| 4dma | 0L8 | Estrogen receptor | / | 0.461 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.461 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.461 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.461 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.461 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.460 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.460 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.459 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.459 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.459 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.459 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.459 | |
| 1gwr | EST | Estrogen receptor | / | 0.458 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.458 | |
| 2ejz | SAH | Diphthine synthase | / | 0.458 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.458 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.458 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 4oez | DHT | Androgen receptor | / | 0.458 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.458 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.457 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.457 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.457 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.457 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.457 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 2fai | 459 | Estrogen receptor | / | 0.456 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.456 | |
| 2ylq | TES | Androgen receptor | / | 0.456 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.456 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.456 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1e7a | PFL | Serum albumin | / | 0.455 | |
| 1err | RAL | Estrogen receptor | / | 0.455 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2emu | SAH | Diphthine synthase | / | 0.455 | |
| 2q7k | TES | Androgen receptor | / | 0.455 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.455 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.455 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.454 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1t74 | DHT | Androgen receptor | / | 0.454 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.454 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.454 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4bmp | FMN | Protein NrdI | / | 0.454 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.454 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.454 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1osv | CHC | Bile acid receptor | / | 0.453 | |
| 1t65 | DHT | Androgen receptor | / | 0.453 | |
| 1t79 | DHT | Androgen receptor | / | 0.453 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.453 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.453 | |
| 2pcm | SAH | Diphthine synthase | / | 0.453 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.453 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.452 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.452 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.452 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.452 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.452 | |
| 3up0 | D7S | aceDAF-12 | / | 0.452 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.452 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1nde | MON | Estrogen receptor beta | / | 0.451 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.451 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.451 | |
| 2g44 | T3O | Estrogen receptor | / | 0.451 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.451 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.451 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.451 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.451 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.451 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.450 | |
| 1u3s | 797 | Estrogen receptor beta | / | 0.450 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.450 | |
| 2q7i | TES | Androgen receptor | / | 0.450 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.450 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.450 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.450 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2pir | DHT | Androgen receptor | / | 0.449 | |
| 2ylo | TES | Androgen receptor | / | 0.449 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.449 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.449 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 1g50 | EST | Estrogen receptor | / | 0.448 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.448 | |
| 1uum | AFI | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.448 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.448 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.448 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.448 | |
| 2q7j | TES | Androgen receptor | / | 0.448 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.448 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.448 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4a9o | A9O | Bromodomain-containing protein 2 | / | 0.448 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.448 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.448 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.448 | |
| 1t7t | DHT | Androgen receptor | / | 0.447 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 1zky | 689 | Estrogen receptor | / | 0.447 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.447 | |
| 2j7y | E3O | Estrogen receptor beta | / | 0.447 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.447 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.447 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.447 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.447 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.447 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.447 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.447 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.446 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.446 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.446 | |
| 4ofr | DHT | Androgen receptor | / | 0.446 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.446 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1t63 | DHT | Androgen receptor | / | 0.445 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1xow | R18 | Androgen receptor | / | 0.445 | |
| 2e8s | SAH | Diphthine synthase | / | 0.445 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.445 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.445 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.445 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.445 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.445 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.445 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.444 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.444 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.444 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.444 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.444 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.444 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.444 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.443 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.443 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.443 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 2piv | DHT | Androgen receptor | / | 0.443 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.443 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.443 | |
| 3b9l | AZZ | Serum albumin | / | 0.443 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.443 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.443 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.443 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1e3g | R18 | Androgen receptor | / | 0.442 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.442 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.442 | |
| 2b1z | 17M | Estrogen receptor | / | 0.442 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.442 | |
| 2eld | SAH | Diphthine synthase | / | 0.442 | |
| 2ele | SAH | Diphthine synthase | / | 0.442 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.442 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.442 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.442 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.442 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.442 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.442 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.442 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.442 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4pxm | EST | Estrogen receptor | / | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.442 | |
| 4zhq | ACP | Tubulin tyrosine ligase | / | 0.442 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.441 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.441 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1u9e | 397 | Estrogen receptor beta | / | 0.441 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.441 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.441 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.441 | |
| 3lu7 | IPX | Serum albumin | / | 0.441 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.441 | |
| 3nwz | COA | BH2602 protein | / | 0.441 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.441 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.441 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.441 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.441 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.441 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.441 | |
| 5ez7 | FAD | Probable FAD-dependent oxidoreductase PA4991 | / | 0.441 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.440 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.440 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.440 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.440 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.440 | |
| 2qgt | EED | Estrogen receptor | / | 0.440 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.440 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.440 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.440 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.440 | |
| 3mje | NDP | AmphB | / | 0.440 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 3qai | XNN | Ketohexokinase | / | 0.440 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.440 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.440 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.440 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.440 |