Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1p2a5BNCyclin-dependent kinase 22.7.11.22

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1p2a5BNCyclin-dependent kinase 22.7.11.221.000
1v1k3FPCyclin-dependent kinase 22.7.11.220.656
2w1hL0FCyclin-dependent kinase 22.7.11.220.616
2c6o4SPCyclin-dependent kinase 22.7.11.220.603
1gih1PUCyclin-dependent kinase 22.7.11.220.598
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.597
1pxmCK5Cyclin-dependent kinase 22.7.11.220.590
2vv9IM9Cyclin-dependent kinase 22.7.11.220.590
1oiqHDUCyclin-dependent kinase 22.7.11.220.586
3rak03ZCyclin-dependent kinase 22.7.11.220.585
3ezvEZVCyclin-dependent kinase 22.7.11.220.580
3rni21ZCyclin-dependent kinase 22.7.11.220.575
3sqq99ZCyclin-dependent kinase 22.7.11.220.574
3rmf20ZCyclin-dependent kinase 22.7.11.220.573
3qtuX44Cyclin-dependent kinase 22.7.11.220.572
2w17I19Cyclin-dependent kinase 22.7.11.220.571
1y91CT9Cyclin-dependent kinase 22.7.11.220.565
2uzoC62Cyclin-dependent kinase 22.7.11.220.564
3s1h56ZCyclin-dependent kinase 22.7.11.220.564
4fkr45KCyclin-dependent kinase 22.7.11.220.562
2w05FRTCyclin-dependent kinase 22.7.11.220.561
1oitHDTCyclin-dependent kinase 22.7.11.220.558
2w06FRVCyclin-dependent kinase 22.7.11.220.557
3qxpX64Cyclin-dependent kinase 22.7.11.220.557
3lfnA27Cyclin-dependent kinase 22.7.11.220.556
3qtzX42Cyclin-dependent kinase 22.7.11.220.556
2r3kSCQCyclin-dependent kinase 22.7.11.220.554
3rk708ZCyclin-dependent kinase 22.7.11.220.553
3rpv26ZCyclin-dependent kinase 22.7.11.220.553
3ti1B49Cyclin-dependent kinase 22.7.11.220.553
1g5sI17Cyclin-dependent kinase 22.7.11.220.551
3qtxX43Cyclin-dependent kinase 22.7.11.220.551
3qxoX65Cyclin-dependent kinase 22.7.11.220.551
2c6iDT1Cyclin-dependent kinase 22.7.11.220.550
4bgh3I6Cyclin-dependent kinase 22.7.11.220.550
2r3lSCWCyclin-dependent kinase 22.7.11.220.549
3rm719ZCyclin-dependent kinase 22.7.11.220.548
2xmyCDKCyclin-dependent kinase 22.7.11.220.547
3qqkX02Cyclin-dependent kinase 22.7.11.220.546
3rjc06ZCyclin-dependent kinase 22.7.11.220.546
4fkt48KCyclin-dependent kinase 22.7.11.220.546
1gii1PUCyclin-dependent kinase 22.7.11.220.545
3ral04ZCyclin-dependent kinase 22.7.11.220.545
1fvv107Cyclin-dependent kinase 22.7.11.220.543
1ykr628Cyclin-dependent kinase 22.7.11.220.542
3r9dX6BCyclin-dependent kinase 22.7.11.220.542
4fkw62KCyclin-dependent kinase 22.7.11.220.542
2uznC96Cyclin-dependent kinase 22.7.11.220.541
3r71X86Cyclin-dependent kinase 22.7.11.220.541
3rk909ZCyclin-dependent kinase 22.7.11.220.541
3r7yZ04Cyclin-dependent kinase 22.7.11.220.540
2r3jSCJCyclin-dependent kinase 22.7.11.220.539
2r3p3SCCyclin-dependent kinase 22.7.11.220.539
3qzgX67Cyclin-dependent kinase 22.7.11.220.539
1pxpCK8Cyclin-dependent kinase 22.7.11.220.538
2bheBRYCyclin-dependent kinase 22.7.11.220.538
2bhhRYUCyclin-dependent kinase 22.7.11.220.536
1pxlCK4Cyclin-dependent kinase 22.7.11.220.535
1ke9LS5Cyclin-dependent kinase 22.7.11.220.534
1w0xOLOCyclin-dependent kinase 22.7.11.220.534
2b55D31Cyclin-dependent kinase 22.7.11.220.534
4fx360KCyclin-dependent kinase 22.7.11.220.534
2vtsLZCCyclin-dependent kinase 22.7.11.220.533
4fkv61KCyclin-dependent kinase 22.7.11.220.533
2btsU32Cyclin-dependent kinase 22.7.11.220.532
3r7uX96Cyclin-dependent kinase 22.7.11.220.531
3s2pPMUCyclin-dependent kinase 22.7.11.220.531
3sw719KCyclin-dependent kinase 22.7.11.220.530
3lfqA28Cyclin-dependent kinase 22.7.11.220.529
3r73X87Cyclin-dependent kinase 22.7.11.220.529
3rkb12ZCyclin-dependent kinase 22.7.11.220.528
3sw418KCyclin-dependent kinase 22.7.11.220.528
2c69CT8Cyclin-dependent kinase 22.7.11.220.527
2r3mSCXCyclin-dependent kinase 22.7.11.220.527
4fko20KCyclin-dependent kinase 22.7.11.220.527
3raiX85Cyclin-dependent kinase 22.7.11.220.526
3wblPDYCyclin-dependent kinase 22.7.11.220.526
4ek816KCyclin-dependent kinase 22.7.11.220.526
1pyePM1Cyclin-dependent kinase 22.7.11.220.525
2vthLZ2Cyclin-dependent kinase 22.7.11.220.525
3iggEFQCyclin-dependent kinase 22.7.11.220.525
3qu0X40Cyclin-dependent kinase 22.7.11.220.525
4fkpLS5Cyclin-dependent kinase 22.7.11.220.525
3ezrEZRCyclin-dependent kinase 22.7.11.220.524
1urwI1PCyclin-dependent kinase 22.7.11.220.523
3r8lZ30Cyclin-dependent kinase 22.7.11.220.523
3pj8404Cyclin-dependent kinase 22.7.11.220.522
3qtrX36Cyclin-dependent kinase 22.7.11.220.522
3rk507ZCyclin-dependent kinase 22.7.11.220.522
3rpy27ZCyclin-dependent kinase 22.7.11.220.522
2r3iSCFCyclin-dependent kinase 22.7.11.220.521
4fkq42KCyclin-dependent kinase 22.7.11.220.521
2duv371Cyclin-dependent kinase 22.7.11.220.519
2fvdLIACyclin-dependent kinase 22.7.11.220.518
2uzbC75Cyclin-dependent kinase 22.7.11.220.518
3roy22ZCyclin-dependent kinase 22.7.11.220.518
3qqfX07Cyclin-dependent kinase 22.7.11.220.517
2a0cCK9Cyclin-dependent kinase 22.7.11.220.516
3r6xX84Cyclin-dependent kinase 22.7.11.220.516
3le62BZCyclin-dependent kinase 22.7.11.220.515
3r9hZ67Cyclin-dependent kinase 22.7.11.220.515
1pkdUCNCyclin-dependent kinase 22.7.11.220.513
1h1r6CPCyclin-dependent kinase 22.7.11.220.512
1pxkCK3Cyclin-dependent kinase 22.7.11.220.512
4lyn1YGCyclin-dependent kinase 22.7.11.220.512
2c6lDT4Cyclin-dependent kinase 22.7.11.220.510
3qruX19Cyclin-dependent kinase 22.7.11.220.510
4acm7YGCyclin-dependent kinase 22.7.11.220.509
1w8cN69Cyclin-dependent kinase 22.7.11.220.508
1ke6LS2Cyclin-dependent kinase 22.7.11.220.507
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.507
2vu3LZECyclin-dependent kinase 22.7.11.220.507
3rm618ZCyclin-dependent kinase 22.7.11.220.506
1oiyN41Cyclin-dependent kinase 22.7.11.220.505
1ckpPVBCyclin-dependent kinase 22.7.11.220.504
1di8DTQCyclin-dependent kinase 22.7.11.220.504
1oguST8Cyclin-dependent kinase 22.7.11.220.504
1pxoCK7Cyclin-dependent kinase 22.7.11.220.504
1r78FMDCyclin-dependent kinase 22.7.11.220.504
2b52D42Cyclin-dependent kinase 22.7.11.220.504
2r64740Cyclin-dependent kinase 22.7.11.220.504
3lfsA07Cyclin-dependent kinase 22.7.11.220.504
3uli1N3Cyclin-dependent kinase 22.7.11.220.504
4ek610KCyclin-dependent kinase 22.7.11.220.504
1aq1STUCyclin-dependent kinase 22.7.11.220.503
1oirHDYCyclin-dependent kinase 22.7.11.220.503
2uzdC85Cyclin-dependent kinase 22.7.11.220.503
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.503
4eor4SPCyclin-dependent kinase 22.7.11.220.503
3rpo24ZCyclin-dependent kinase 22.7.11.220.502
1dm2HMDCyclin-dependent kinase 22.7.11.220.501
3r7iX9ICyclin-dependent kinase 22.7.11.220.501
2wxvWXVCyclin-dependent kinase 22.7.11.220.500
3s0o50ZCyclin-dependent kinase 22.7.11.220.500
1h1s4SPCyclin-dependent kinase 22.7.11.220.499
2wihP48Cyclin-dependent kinase 22.7.11.220.498
3qwjX6ACyclin-dependent kinase 22.7.11.220.498
1ke8LS4Cyclin-dependent kinase 22.7.11.220.497
3r8pZ46Cyclin-dependent kinase 22.7.11.220.497
3r7vZ02Cyclin-dependent kinase 22.7.11.220.496
3qzfX66Cyclin-dependent kinase 22.7.11.220.495
2vtqLZACyclin-dependent kinase 22.7.11.220.494
3r1sX73Cyclin-dependent kinase 22.7.11.220.494
4fks46KCyclin-dependent kinase 22.7.11.220.494
3be9P04Casein kinase II subunit alpha2.7.11.10.493
3qzhX69Cyclin-dependent kinase 22.7.11.220.493
2c6mDT5Cyclin-dependent kinase 22.7.11.220.492
2vttLZDCyclin-dependent kinase 22.7.11.220.492
3unk0BYCyclin-dependent kinase 22.7.11.220.492
3r1yX76Cyclin-dependent kinase 22.7.11.220.491
3r8zZ63Cyclin-dependent kinase 22.7.11.220.491
1fvt106Cyclin-dependent kinase 22.7.11.220.490
2r3r6SCCyclin-dependent kinase 22.7.11.220.490
3qqhX0ACyclin-dependent kinase 22.7.11.220.490
3sheI85MAP kinase-activated protein kinase 32.7.11.10.490
4erwSTUCyclin-dependent kinase 22.7.11.220.490
4ez30S0Cyclin-dependent kinase 22.7.11.220.490
1e9hINRCyclin-dependent kinase 22.7.11.220.489
2pvnP63Casein kinase II subunit alpha2.7.11.10.489
3ig7EFPCyclin-dependent kinase 22.7.11.220.489
2btrU73Cyclin-dependent kinase 22.7.11.220.488
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.488
3fz1B98Cyclin-dependent kinase 22.7.11.220.488
2iw94SPCyclin-dependent kinase 22.7.11.220.487
3ddqRRCCyclin-dependent kinase 22.7.11.220.487
4bcmT7ZCyclin-dependent kinase 22.7.11.220.487
4bcpT3CCyclin-dependent kinase 22.7.11.220.487
3qqlX03Cyclin-dependent kinase 22.7.11.220.486
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.485
2eufLQQCyclin-dependent kinase 62.7.11.220.484
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.484
4qmpDKISerine/threonine-protein kinase 242.7.11.10.484
2cchATPCyclin-dependent kinase 22.7.11.220.483
2r3q5SCCyclin-dependent kinase 22.7.11.220.483
2wpa889Cyclin-dependent kinase 22.7.11.220.483
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.482
4aqc88ATyrosine-protein kinase JAK2/0.482
2j9mPY8Cyclin-dependent kinase 22.7.11.220.481
4eok4SPCyclin-dependent kinase 22.7.11.220.481
2c6tDT5Cyclin-dependent kinase 22.7.11.220.479
2x1nX1NCyclin-dependent kinase 22.7.11.220.479
4fkg4CKCyclin-dependent kinase 22.7.11.220.479
1gij2PUCyclin-dependent kinase 22.7.11.220.478
3py0SU9Cyclin-dependent kinase 22.7.11.220.478
3rahO1ZCyclin-dependent kinase 22.7.11.220.478
2i40BLZCyclin-dependent kinase 22.7.11.220.477
2iw84SPCyclin-dependent kinase 22.7.11.220.477
3qrtX14Cyclin-dependent kinase 22.7.11.220.476
3ddpRC8Cyclin-dependent kinase 22.7.11.220.475
4ez50RSCyclin-dependent kinase 62.7.11.220.475
3qtqX35Cyclin-dependent kinase 22.7.11.220.474
4bcnT9NCyclin-dependent kinase 22.7.11.220.474
3nux3NVCyclin-dependent kinase 62.7.11.220.473
2c5nCK8Cyclin-dependent kinase 22.7.11.220.472
3qwkX62Cyclin-dependent kinase 22.7.11.220.472
4bcoT6QCyclin-dependent kinase 22.7.11.220.472
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.471
3nynSGVG protein-coupled receptor kinase 62.7.11.160.471
4bbfO19Tyrosine-protein kinase JAK2/0.470
1oi9N20Cyclin-dependent kinase 22.7.11.220.469
1vyzN5BCyclin-dependent kinase 22.7.11.220.469
2xnbY8LCyclin-dependent kinase 22.7.11.220.469
3r28XA0Cyclin-dependent kinase 22.7.11.220.469
3r8vZ62Cyclin-dependent kinase 22.7.11.220.469
3rzb02ZCyclin-dependent kinase 22.7.11.220.469
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.469
4fkj11KCyclin-dependent kinase 22.7.11.220.468
1oiuN76Cyclin-dependent kinase 22.7.11.220.467
3ql8X01Cyclin-dependent kinase 22.7.11.220.467
4qmySTUSerine/threonine-protein kinase 242.7.11.10.467
1ke7LS3Cyclin-dependent kinase 22.7.11.220.465
3qx2X63Cyclin-dependent kinase 22.7.11.220.465
3r1qX75Cyclin-dependent kinase 22.7.11.220.465
2r3o2SCCyclin-dependent kinase 22.7.11.220.464
3r9nZ68Cyclin-dependent kinase 22.7.11.220.464
3r9oZ71Cyclin-dependent kinase 22.7.11.220.464
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.463
3dogNNNCyclin-dependent kinase 22.7.11.220.462
3r83Z14Cyclin-dependent kinase 22.7.11.220.462
2b53D23Cyclin-dependent kinase 22.7.11.220.461
3my5RFZCyclin-dependent kinase 22.7.11.220.461
1vyw292Cyclin-dependent kinase 22.7.11.220.460
2pvlP55Casein kinase II subunit alpha2.7.11.10.460
3qziX72Cyclin-dependent kinase 22.7.11.220.460
1eh4IC1Casein kinase I homolog 12.7.11.10.459
1h0w207Cyclin-dependent kinase 22.7.11.220.459
1y8yCT7Cyclin-dependent kinase 22.7.11.220.459
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.459
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.459
1ke5LS1Cyclin-dependent kinase 22.7.11.220.458
2c4g514Cyclin-dependent kinase 22.7.11.220.458
3r7eX88Cyclin-dependent kinase 22.7.11.220.458
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.457
4gub0Y4Casein kinase II subunit alpha2.7.11.10.457
5dr9SKEAurora kinase A2.7.11.10.457
2a4lRRCCyclin-dependent kinase 22.7.11.220.456
3tnwF18Cyclin-dependent kinase 22.7.11.220.456
4ii5ADPCyclin-dependent kinase 22.7.11.220.456
2pvhP19Casein kinase II subunit alpha2.7.11.10.455
2vtrLZBCyclin-dependent kinase 22.7.11.220.455
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.455
1v0oINRCell division control protein 2 homolog2.7.11.220.454
3ggfGVDSerine/threonine-protein kinase 26/0.454
3unj0BXCyclin-dependent kinase 22.7.11.220.454
4eon1ROCyclin-dependent kinase 22.7.11.220.454
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.454
1finATPCyclin-dependent kinase 22.7.11.220.452
1xjdSTUProtein kinase C theta type2.7.11.130.452
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.452
2c6kDT2Cyclin-dependent kinase 22.7.11.220.452
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.452
4ivc1J6Tyrosine-protein kinase JAK1/0.452
2b54D05Cyclin-dependent kinase 22.7.11.220.451
3qtwX3ACyclin-dependent kinase 22.7.11.220.451
4hvh19RTyrosine-protein kinase JAK32.7.10.20.451
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.450
2c68CT6Cyclin-dependent kinase 22.7.11.220.449
2r3fSC8Cyclin-dependent kinase 22.7.11.220.449
3zep1NXTyrosine-protein kinase JAK32.7.10.20.449
3tiz3TICyclin-dependent kinase 22.7.11.220.448
4btjATPTau-tubulin kinase 12.7.11.10.448
2uzeC95Cyclin-dependent kinase 22.7.11.220.447
2uzlC94Cyclin-dependent kinase 22.7.11.220.447
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3eb0DRKUncharacterized protein/0.447
3pxyJWSCyclin-dependent kinase 22.7.11.220.447
3gubGUBDeath-associated protein kinase 12.7.11.10.446
1h1q2A6Cyclin-dependent kinase 22.7.11.220.445
2r3gSC9Cyclin-dependent kinase 22.7.11.220.445
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.445
5dr6SKEAurora kinase A2.7.11.10.445
5dt3ATPAurora kinase A2.7.11.10.445
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.444
1unlRRCCyclin-dependent-like kinase 52.7.11.10.444
4a4qUX9Pol protein/0.444
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.443
2bkzSBCCyclin-dependent kinase 22.7.11.220.443
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.442
4i5cC5ITyrosine-protein kinase JAK1/0.442
2fxdDR7Pol polyprotein/0.441
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.441
5dt0SKEAurora kinase A2.7.11.10.441
4eomATPCyclin-dependent kinase 22.7.11.220.440
4fv6E57Mitogen-activated protein kinase 12.7.11.240.440
4hvi19STyrosine-protein kinase JAK32.7.10.20.440