sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ow3 | GDP | Transforming protein RhoA |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ow3 | GDP | Transforming protein RhoA | / | 1.000 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.562 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.503 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.482 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.480 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.470 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.468 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.467 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.466 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.465 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.464 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.462 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.460 | |
| 3v4f | GNP | GTPase HRas | / | 0.460 | |
| 3lbn | GNP | GTPase HRas | / | 0.456 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.456 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.454 | |
| 4nyi | GNP | GTPase HRas | / | 0.454 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.454 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.453 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.453 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.451 | |
| 4k81 | GTP | GTPase HRas | / | 0.451 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.451 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4dlw | GNP | GTPase HRas | / | 0.447 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.446 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.444 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.444 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.444 | |
| 4nyj | GNP | GTPase HRas | / | 0.444 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.444 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.442 | |
| 3oiu | GNP | GTPase HRas | / | 0.442 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.441 | |
| 3rs5 | GNP | GTPase HRas | / | 0.441 |