sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ot7 | CHC | Bile acid receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ot7 | CHC | Bile acid receptor | / | 1.000 | |
| 1osv | CHC | Bile acid receptor | / | 0.731 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.596 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.489 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.479 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.460 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.460 | |
| 1tw4 | CHD | Fatty acid-binding protein, liver | / | 0.457 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.456 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.456 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.444 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 |