sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ori | SAH | Protein arginine N-methyltransferase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ori | SAH | Protein arginine N-methyltransferase 1 | / | 1.000 | |
| 4qpp | SAH | Protein arginine N-methyltransferase 6 | / | 0.522 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.505 | |
| 4c05 | SAH | Protein arginine N-methyltransferase 6 | / | 0.494 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.464 | |
| 1k6c | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 1rbm | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.458 | |
| 3zuy | TCH | Transporter | / | 0.457 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.457 | |
| 3el4 | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4fr0 | SAM | Arsenic methyltransferase | / | 0.449 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.448 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.444 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3b89 | 5GP | 16S rRNA methylase | / | 0.442 |