Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1oo6SN2Oxygen-insensitive NAD(P)H nitroreductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1oo6SN2Oxygen-insensitive NAD(P)H nitroreductase/1.000
4a81DXCMajor pollen allergen Bet v 1-A/0.481
1oonBELOxygen-insensitive NAD(P)H nitroreductase/0.477
5hs1VORLanosterol 14-alpha demethylase/0.464
4bfzZVZPantothenate kinase2.7.1.330.463
4rvfTYDD-mycarose 3-C-methyltransferase/0.463
2lfoGCHFatty acid-binding protein, liver/0.454
4zj8SUVOrexin receptor type 1/0.452
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.451
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.451
4a83DXCMajor pollen allergen Bet v 1-A/0.451
2ikuLIYRenin3.4.23.150.450
3zeiAWHO-acetylserine sulfhydrylase/0.450
1pqc444Oxysterols receptor LXR-beta/0.449
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
4e0u0MVCyclic dipeptide N-prenyltransferase/0.448
1rpwDIDHTH-type transcriptional regulator QacR/0.444
2g247IGRenin3.4.23.150.444
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.443
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.443
3pn1IVHDNA ligase/0.443
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.442
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.442
3oadLPORenin3.4.23.150.442
4h6pFMNChromate reductase/0.441
4i6gFADCryptochrome-2/0.441
1ry8RUTAldo-keto reductase family 1 member C3/0.440
3bgxTMPThymidylate synthase/0.440
4dc0NDPPutative ketoacyl reductase1.3.10.440