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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1om1IQACasein kinase II subunit alpha2.7.11.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1om1IQACasein kinase II subunit alpha2.7.11.11.000
2pvhP19Casein kinase II subunit alpha2.7.11.10.657
1m2rMNYCasein kinase II subunit alpha2.7.11.10.631
3be9P04Casein kinase II subunit alpha2.7.11.10.587
4dgo0JWCasein kinase II subunit alpha2.7.11.10.586
1m2pHNACasein kinase II subunit alpha2.7.11.10.573
4dgnLU2Casein kinase II subunit alpha2.7.11.10.571
3at3ATKCasein kinase II subunit alpha2.7.11.10.569
2pvlP55Casein kinase II subunit alpha2.7.11.10.562
2pvnP63Casein kinase II subunit alpha2.7.11.10.554
4jr7GNPCasein kinase II subunit alpha2.7.11.10.548
4gub0Y4Casein kinase II subunit alpha2.7.11.10.541
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.536
4dgmAGICasein kinase II subunit alpha2.7.11.10.533
4jqeANPCasein kinase II subunit alpha2.7.11.10.531
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.529
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.525
3q9xEMOCasein kinase II subunit alpha2.7.11.10.523
4grb0XGCasein kinase II subunit alpha2.7.11.10.521
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.518
4anmWULCasein kinase II subunit alpha2.7.11.10.517
3at4CCKCasein kinase II subunit alpha2.7.11.10.514
5cshATPCasein kinase II subunit alpha2.7.11.10.514
3u4uLNHCasein kinase II subunit alpha2.7.11.10.513
2p33J07Mitogen-activated protein kinase 102.7.11.240.511
1dayGNPCasein kinase II subunit alpha2.7.11.10.507
2xa4AZ5Tyrosine-protein kinase JAK2/0.507
4hge15VTyrosine-protein kinase JAK2/0.506
5cvfATPCasein kinase II subunit alpha2.7.11.10.506
2iw94SPCyclin-dependent kinase 22.7.11.220.503
1pyePM1Cyclin-dependent kinase 22.7.11.220.502
2h96893Mitogen-activated protein kinase 82.7.11.240.502
4jia1K3Tyrosine-protein kinase JAK2/0.502
2w05FRTCyclin-dependent kinase 22.7.11.220.501
3eljGS7Mitogen-activated protein kinase 82.7.11.240.501
5cvhADPCasein kinase II subunit alpha2.7.11.10.500
1pmn984Mitogen-activated protein kinase 102.7.11.240.499
3cgfJNFMitogen-activated protein kinase 102.7.11.240.499
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.499
5e8wSTUTGF-beta receptor type-12.7.11.300.499
1dawANPCasein kinase II subunit alpha2.7.11.10.498
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.498
2x1nX1NCyclin-dependent kinase 22.7.11.220.498
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.497
3s1h56ZCyclin-dependent kinase 22.7.11.220.497
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.497
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.497
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.497
2c6tDT5Cyclin-dependent kinase 22.7.11.220.496
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.496
4aqc88ATyrosine-protein kinase JAK2/0.496
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.495
3gubGUBDeath-associated protein kinase 12.7.11.10.493
3nga3NGCasein kinase II subunit alpha2.7.11.10.493
4iwd1JCHepatocyte growth factor receptor2.7.10.10.493
2iw84SPCyclin-dependent kinase 22.7.11.220.492
4bgg844Activin receptor type-12.7.11.300.492
2b7aIZATyrosine-protein kinase JAK2/0.491
2zdt46CMitogen-activated protein kinase 102.7.11.240.491
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.491
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.491
3lpbNVBTyrosine-protein kinase JAK2/0.490
3rak03ZCyclin-dependent kinase 22.7.11.220.490
3rvg17PTyrosine-protein kinase JAK2/0.490
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.490
1aq1STUCyclin-dependent kinase 22.7.11.220.489
1lp4ANPCasein kinase II subunit alpha2.7.11.10.487
2xikJ60Serine/threonine-protein kinase 252.7.11.10.487
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.487
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.487
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.487
3r9dX6BCyclin-dependent kinase 22.7.11.220.486
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.485
1oi9N20Cyclin-dependent kinase 22.7.11.220.484
1pkdUCNCyclin-dependent kinase 22.7.11.220.484
3ttjJBIMitogen-activated protein kinase 102.7.11.240.484
4lfiGNPCasein kinase II subunit alpha2.7.11.10.484
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.484
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.483
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.483
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.483
2bhhRYUCyclin-dependent kinase 22.7.11.220.482
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.482
3rk507ZCyclin-dependent kinase 22.7.11.220.482
4e4m0NHTyrosine-protein kinase JAK2/0.482
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.482
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.482
1di8DTQCyclin-dependent kinase 22.7.11.220.481
1xjdSTUProtein kinase C theta type2.7.11.130.481
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.481
1vjy460TGF-beta receptor type-12.7.11.300.480
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.480
1eh4IC1Casein kinase I homolog 12.7.11.10.479
1m2qMNXCasein kinase II subunit alpha2.7.11.10.479
4k33ACPFibroblast growth factor receptor 32.7.10.10.479
3vt8YI3Vitamin D3 receptor/0.478
4wkqIREEpidermal growth factor receptor2.7.10.10.478
3bhy7CPDeath-associated protein kinase 3/0.477
3oroAGSSerine/threonine protein kinase/0.476
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.476
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.475
2cchATPCyclin-dependent kinase 22.7.11.220.475
2pvmP29Casein kinase II subunit alpha2.7.11.10.475
3zh8C58Protein kinase C iota type2.7.11.130.475
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.475
4qmpDKISerine/threonine-protein kinase 242.7.11.10.475
2zjwREFCasein kinase II subunit alpha2.7.11.10.474
3rmf20ZCyclin-dependent kinase 22.7.11.220.474
4hgt15GCasein kinase I isoform delta2.7.11.10.474
2in6839Wee1-like protein kinase2.7.10.20.473
2pvjP44Casein kinase II subunit alpha2.7.11.10.473
4hvi19STyrosine-protein kinase JAK32.7.10.20.473
4o0wADNAurora kinase A2.7.11.10.473
1e9hINRCyclin-dependent kinase 22.7.11.220.472
1g5sI17Cyclin-dependent kinase 22.7.11.220.472
1gih1PUCyclin-dependent kinase 22.7.11.220.472
1pmv537Mitogen-activated protein kinase 102.7.11.240.472
2uzbC75Cyclin-dependent kinase 22.7.11.220.472
2zdu446Mitogen-activated protein kinase 102.7.11.240.472
3l8p0CEAngiopoietin-1 receptor2.7.10.10.472
3rni21ZCyclin-dependent kinase 22.7.11.220.472
4acm7YGCyclin-dependent kinase 22.7.11.220.472
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.472
4gmy0X5Tyrosine-protein kinase JAK2/0.472
4jajXU1Aurora kinase A2.7.11.10.472
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.472
2uzlC94Cyclin-dependent kinase 22.7.11.220.471
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.471
3axwTIDCasein kinase II subunit alpha2.7.11.10.471
3ral04ZCyclin-dependent kinase 22.7.11.220.471
4bgh3I6Cyclin-dependent kinase 22.7.11.220.471
4c61LMMTyrosine-protein kinase JAK2/0.471
4g1wG1WMitogen-activated protein kinase 82.7.11.240.471
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.471
1y91CT9Cyclin-dependent kinase 22.7.11.220.470
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.470
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.470
3q9zTXQCasein kinase II subunit alpha2.7.11.10.470
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.470
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.470
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.470
5cu6ATPCasein kinase II subunit alpha2.7.11.10.470
3ggfGVDSerine/threonine-protein kinase 26/0.469
4ewhT77Activated CDC42 kinase 1/0.469
4mwhATPCasein kinase II subunit alpha2.7.11.10.469
1fvv107Cyclin-dependent kinase 22.7.11.220.468
1ol5ADPAurora kinase A2.7.11.10.468
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.468
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.468
4eok4SPCyclin-dependent kinase 22.7.11.220.468
4erwSTUCyclin-dependent kinase 22.7.11.220.468
4q71FADBifunctional protein PutA/0.468
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.467
3vt7VDXVitamin D3 receptor/0.467
4c62XWWTyrosine-protein kinase JAK2/0.467
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.467
4ez50RSCyclin-dependent kinase 62.7.11.220.467
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.467
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.467
4y93746Tyrosine-protein kinase/0.467
1oiuN76Cyclin-dependent kinase 22.7.11.220.466
1oiyN41Cyclin-dependent kinase 22.7.11.220.466
3cgoJNOMitogen-activated protein kinase 102.7.11.240.466
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.466
3rpv26ZCyclin-dependent kinase 22.7.11.220.466
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.466
2eufLQQCyclin-dependent kinase 62.7.11.220.465
3hmm855TGF-beta receptor type-12.7.11.300.465
3uli1N3Cyclin-dependent kinase 22.7.11.220.465
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.465
3vt9YI4Vitamin D3 receptor/0.465
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.465
1rfuADPPyridoxal kinase2.7.1.350.464
1u4dDBQActivated CDC42 kinase 1/0.464
2dwbANPAurora kinase A2.7.11.10.464
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.464
3ddpRC8Cyclin-dependent kinase 22.7.11.220.464
3il1B5DGlutamate receptor 2/0.464
3owk18ECasein kinase II subunit alpha2.7.11.10.464
4ivc1J6Tyrosine-protein kinase JAK1/0.464
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.464
4kioG5KTyrosine-protein kinase ITK/TSK2.7.10.20.464
1oirHDYCyclin-dependent kinase 22.7.11.220.463
1xddAAYIntegrin alpha-L/0.463
2q9fC3SCholesterol 24-hydroxylase/0.463
3gu6ADPDeath-associated protein kinase 12.7.11.10.463
3gxlQIGTGF-beta receptor type-12.7.11.300.463
3qu0X40Cyclin-dependent kinase 22.7.11.220.463
3r83Z14Cyclin-dependent kinase 22.7.11.220.463
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.463
5dr6SKEAurora kinase A2.7.11.10.463
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.462
2b53D23Cyclin-dependent kinase 22.7.11.220.462
2csnCKICasein kinase I homolog 12.7.11.10.462
2vv9IM9Cyclin-dependent kinase 22.7.11.220.462
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.462
3le62BZCyclin-dependent kinase 22.7.11.220.462
3nszANPCasein kinase II subunit alpha2.7.11.10.462
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.462
3qtxX43Cyclin-dependent kinase 22.7.11.220.462
4btjADPTau-tubulin kinase 12.7.11.10.462
4fi1ATPCasein kinase II subunit alpha2.7.11.10.462
4hvh19RTyrosine-protein kinase JAK32.7.10.20.462
5e8ySTUTGF-beta receptor type-22.7.11.300.462
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.461
1w6hTITPlasmepsin-23.4.23.390.461
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.461
3ormAGSSerine/threonine protein kinase/0.461
4ek816KCyclin-dependent kinase 22.7.11.220.461
5e92ANPTGF-beta receptor type-22.7.11.300.461
1h1s4SPCyclin-dependent kinase 22.7.11.220.460
1pxlCK4Cyclin-dependent kinase 22.7.11.220.460
3gw9VNILanosterol 14-alpha-demethylase/0.460
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.460
4zseANPEpidermal growth factor receptor2.7.10.10.460
1bygSTUTyrosine-protein kinase CSK/0.459
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.459
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.459
3iok1P6Tyrosine-protein kinase JAK2/0.459
3k5uPFQAurora kinase A2.7.11.10.459
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.459
3rk708ZCyclin-dependent kinase 22.7.11.220.459
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4btjATPTau-tubulin kinase 12.7.11.10.459
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.459
5cnnANPEpidermal growth factor receptor2.7.10.10.459
1gij2PUCyclin-dependent kinase 22.7.11.220.458
1yvj4STTyrosine-protein kinase JAK32.7.10.20.458
3ddqRRCCyclin-dependent kinase 22.7.11.220.458
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.458
3lfnA27Cyclin-dependent kinase 22.7.11.220.458
3lfqA28Cyclin-dependent kinase 22.7.11.220.458
1gii1PUCyclin-dependent kinase 22.7.11.220.457
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.457
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2j0j4STFocal adhesion kinase 12.7.10.20.457
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.457
3kvxFMYMitogen-activated protein kinase 102.7.11.240.457
3zmmF9JTyrosine-protein kinase JAK2/0.457
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4c02TAKActivin receptor type-12.7.11.300.457
4dpuAGSMevalonate diphosphate decarboxylase/0.457
4dymIYZActivin receptor type-12.7.11.300.457
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.457
4wsqKSAAP2-associated protein kinase 12.7.11.10.457
5drdATPAurora kinase A2.7.11.10.457
5dt0SKEAurora kinase A2.7.11.10.457
1pxmCK5Cyclin-dependent kinase 22.7.11.220.456
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.456
2po7CHDFerrochelatase, mitochondrial4.99.1.10.456
2vu3LZECyclin-dependent kinase 22.7.11.220.456
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.456
3slkNDPPolyketide synthase extender module 2/0.456
3t2kFADSulfide-quinone reductase/0.456
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.456
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.456
4i22IREEpidermal growth factor receptor2.7.10.10.456
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.456
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.455
2izuP01Casein kinase I isoform gamma-32.7.11.10.455
2w17I19Cyclin-dependent kinase 22.7.11.220.455
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.455
1ke6LS2Cyclin-dependent kinase 22.7.11.220.454
1u54ACPActivated CDC42 kinase 1/0.454
1v9aSAHUncharacterized protein/0.454
2bheBRYCyclin-dependent kinase 22.7.11.220.454
3slz3TLPutative gag-pro-pol polyprotein/0.454
3v3vMYUMitogen-activated protein kinase 82.7.11.240.454
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.454
3zep1NXTyrosine-protein kinase JAK32.7.10.20.454
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.454
4fkv61KCyclin-dependent kinase 22.7.11.220.454
4hgs15GCasein kinase I isoform gamma-32.7.11.10.454
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.454
4ux9ANPMitogen-activated protein kinase 82.7.11.240.454
2c5yMTWCyclin-dependent kinase 22.7.11.220.453
2r3lSCWCyclin-dependent kinase 22.7.11.220.453
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.453
2z2w770Wee1-like protein kinase2.7.10.20.453
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3lpkZ76Beta-secretase 13.4.23.460.453
3qxpX64Cyclin-dependent kinase 22.7.11.220.453
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.453
4fv6E57Mitogen-activated protein kinase 12.7.11.240.453
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.453
4lrjANPUncharacterized protein/0.453
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.452
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.452
2c6o4SPCyclin-dependent kinase 22.7.11.220.452
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.452
2w06FRVCyclin-dependent kinase 22.7.11.220.452
2xnbY8LCyclin-dependent kinase 22.7.11.220.452
3bi6396Wee1-like protein kinase2.7.10.20.452
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.452
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.452
3uyt0CKCasein kinase I isoform delta2.7.11.10.452
3uzp0CKCasein kinase I isoform delta2.7.11.10.452
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.452
4j95ACPFibroblast growth factor receptor 2/0.452
4ji91M3Tyrosine-protein kinase JAK2/0.452
1h1r6CPCyclin-dependent kinase 22.7.11.220.451
2excJNKMitogen-activated protein kinase 102.7.11.240.451
2qo9ANPEphrin type-A receptor 32.7.10.10.451
2r3jSCJCyclin-dependent kinase 22.7.11.220.451
2vttLZDCyclin-dependent kinase 22.7.11.220.451
3c13EMOCasein kinase II subunit alpha2.7.11.10.451
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.451
3qzgX67Cyclin-dependent kinase 22.7.11.220.451
3rk909ZCyclin-dependent kinase 22.7.11.220.451
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.451
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.451
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4enhFVXCholesterol 24-hydroxylase/0.451
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.451
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.451
5ap7SVEDual specificity protein kinase TTK2.7.12.10.451
5dr9SKEAurora kinase A2.7.11.10.451
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.450
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.450
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.450
2iko7IGRenin3.4.23.150.450
2izrBRKCasein kinase I isoform gamma-32.7.11.10.450
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.450
3oibFDAPutative acyl-CoA dehydrogenase/0.450
3qtzX42Cyclin-dependent kinase 22.7.11.220.450
4a8v2ANMajor pollen allergen Bet v 1-J/0.450
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4bbe3O4Tyrosine-protein kinase JAK2/0.450
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.450
4ly91YYGlucokinase regulatory protein/0.450
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.450
4ryvZEAProtein LlR18A/0.450
5dt3ATPAurora kinase A2.7.11.10.450
1oguST8Cyclin-dependent kinase 22.7.11.220.449
1w0xOLOCyclin-dependent kinase 22.7.11.220.449
1yw2PGJMitogen-activated protein kinase 14/0.449
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.449
2a4lRRCCyclin-dependent kinase 22.7.11.220.449
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.449
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.449
2uzeC95Cyclin-dependent kinase 22.7.11.220.449
2v7a627Tyrosine-protein kinase ABL12.7.10.20.449
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.449
2w1fL0FAurora kinase A2.7.11.10.449
2wotZZGTGF-beta receptor type-12.7.11.300.449
2zbaZBATrichothecene 3-O-acetyltransferase/0.449
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.449
3eb0DRKUncharacterized protein/0.449
3pe2E1BCasein kinase II subunit alpha2.7.11.10.449
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.449
4ocvANPAminoglycoside phosphotransferase/0.449
1t7i017Gag-Pol polyprotein3.4.23.160.448
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.448
2izt23DCasein kinase I isoform gamma-32.7.11.10.448
2j0m4STFocal adhesion kinase 12.7.10.20.448
2np8CC3Aurora kinase A2.7.11.10.448
2wpa889Cyclin-dependent kinase 22.7.11.220.448
2znq401Peroxisome proliferator-activated receptor delta/0.448
3i60E86Mitogen-activated protein kinase 12.7.11.240.448
3qtuX44Cyclin-dependent kinase 22.7.11.220.448
3sm2478Putative gag-pro-pol polyprotein/0.448
3sw719KCyclin-dependent kinase 22.7.11.220.448
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.448
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.448
4c58824Cyclin-G-associated kinase2.7.11.10.448
4eor4SPCyclin-dependent kinase 22.7.11.220.448
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.448
4ix6ADPUncharacterized protein/0.448
5cnoANPEpidermal growth factor receptor2.7.10.10.448
1bwsNDPGDP-L-fucose synthase/0.447
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.447
2igoFADPyranose 2-oxidase/0.447
2izsBRQCasein kinase I isoform gamma-32.7.11.10.447
2uzdC85Cyclin-dependent kinase 22.7.11.220.447
2w1hL0FCyclin-dependent kinase 22.7.11.220.447
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.447
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.447
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.447
3r7eX88Cyclin-dependent kinase 22.7.11.220.447
3sheI85MAP kinase-activated protein kinase 32.7.11.10.447
3sw418KCyclin-dependent kinase 22.7.11.220.447
3u9eCOALmo1369 protein/0.447
3umw596Serine/threonine-protein kinase pim-12.7.11.10.447
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.447
4btmF8ETau-tubulin kinase 12.7.11.10.447
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4fko20KCyclin-dependent kinase 22.7.11.220.447
4fob0USALK tyrosine kinase receptor2.7.10.10.447
4lopSB4Mitogen-activated protein kinase 14/0.447
1p2a5BNCyclin-dependent kinase 22.7.11.220.446
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.446
2ckeIQUDeath-associated protein kinase 2/0.446
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.446
2jkqVG8Focal adhesion kinase 12.7.10.20.446
2o2u738Mitogen-activated protein kinase 102.7.11.240.446
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.446
3lltANPProtein serine/threonine kinase-1/0.446
3nynSGVG protein-coupled receptor kinase 62.7.11.160.446
3unk0BYCyclin-dependent kinase 22.7.11.220.446
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.446
4ivd15TTyrosine-protein kinase JAK1/0.446
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.446
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.445
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.445
1v0oINRCell division control protein 2 homolog2.7.11.220.445
1y0s331Peroxisome proliferator-activated receptor delta/0.445
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.445
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.445
2wihP48Cyclin-dependent kinase 22.7.11.220.445
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.445
3rm618ZCyclin-dependent kinase 22.7.11.220.445
3ttiKBIMitogen-activated protein kinase 102.7.11.240.445
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.445
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
1csnATPCasein kinase I homolog 12.7.11.10.444
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.444
2ds11CDCyclin-dependent kinase 22.7.11.220.444
3abaFLICytochrome P450/0.444
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.444
3dogNNNCyclin-dependent kinase 22.7.11.220.444
3fl8RARDihydrofolate reductase/0.444
3gggNADPrephenate dehydrogenase/0.444
3lq5SLQCyclin-dependent kinase 92.7.11.220.444
3pj8404Cyclin-dependent kinase 22.7.11.220.444
3t8oATPRhodopsin kinase/0.444
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.444
4bcpT3CCyclin-dependent kinase 22.7.11.220.444
4fkr45KCyclin-dependent kinase 22.7.11.220.444
4i5cC5ITyrosine-protein kinase JAK1/0.444
4j97ACPFibroblast growth factor receptor 2/0.444
5auxKMPDeath-associated protein kinase 12.7.11.10.444
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.443
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
3begANPSRSF protein kinase 12.7.11.10.443
3gu83GUDeath-associated protein kinase 12.7.11.10.443
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.443
3r8lZ30Cyclin-dependent kinase 22.7.11.220.443
3rkb12ZCyclin-dependent kinase 22.7.11.220.443
3t2zFADSulfide-quinone reductase/0.443
3wowANPCasein kinase II subunit alpha2.7.11.10.443
4aknS5BBromodomain-containing protein 2/0.443
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.443
4bcoT6QCyclin-dependent kinase 22.7.11.220.443
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.443
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.443
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.443
4iva1J5Tyrosine-protein kinase JAK2/0.443
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.443
4r20AERCytochrome P450 family 17 polypeptide 2/0.443
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.443
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
5e8xSTUTGF-beta receptor type-12.7.11.300.443
2uzoC62Cyclin-dependent kinase 22.7.11.220.442
2vagV25Dual specificity protein kinase CLK12.7.12.10.442
2yn8STUEphrin type-B receptor 42.7.10.10.442
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3mb714ICasein kinase II subunit alpha2.7.11.10.442
3nbvANPKetohexokinase/0.442
3sqq99ZCyclin-dependent kinase 22.7.11.220.442
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.442
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.442
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.442
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.442
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4hvg19QTyrosine-protein kinase JAK32.7.10.20.442
4ivb1J5Tyrosine-protein kinase JAK1/0.442
4qnyANPMitogen activated protein kinase, putative/0.442
4yryFADGlutamate synthase, beta subunit/0.442
5a3cNADSIR2 family protein/0.442
5dt4ATPAurora kinase A2.7.11.10.442
1e1xNW1Cyclin-dependent kinase 22.7.11.220.441
1hshMK1Gag-Pol polyprotein/0.441
1jioDEB6-deoxyerythronolide B hydroxylase/0.441
2b1pAIZMitogen-activated protein kinase 102.7.11.240.441
2b55D31Cyclin-dependent kinase 22.7.11.220.441
2bkzSBCCyclin-dependent kinase 22.7.11.220.441
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2vf0F89Thymidylate synthase/0.441
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.441
2xs0ANPMitogen-activated protein kinase 82.7.11.240.441
3mtfA3FActivin receptor type-12.7.11.300.441
3my5RFZCyclin-dependent kinase 22.7.11.220.441
3nux3NVCyclin-dependent kinase 62.7.11.220.441
3oqkS52Renin3.4.23.150.441
3ortAGSSerine/threonine protein kinase/0.441
3ql8X01Cyclin-dependent kinase 22.7.11.220.441
3t14FADSulfide-quinone reductase/0.441
3tnwF18Cyclin-dependent kinase 22.7.11.220.441
3tz3B36Acetyl-CoA carboxylase/0.441
4bcnT9NCyclin-dependent kinase 22.7.11.220.441
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4fkw62KCyclin-dependent kinase 22.7.11.220.441
4fx360KCyclin-dependent kinase 22.7.11.220.441
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.441
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.441
4qmzB49Serine/threonine-protein kinase 242.7.11.10.441
4utdACPAurora kinase A2.7.11.10.441
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.441
4xgxADPFAD:protein FMN transferase/0.441
5av2KMPDeath-associated protein kinase 12.7.11.10.441
5dp2NAPCurF/0.441
1h1q2A6Cyclin-dependent kinase 22.7.11.220.440
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.440
2etm7PYFocal adhesion kinase 12.7.10.20.440
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.440
2xmyCDKCyclin-dependent kinase 22.7.11.220.440
2xngA0HAurora kinase A2.7.11.10.440
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.440
3ttp017Gag-Pol polyprotein3.4.23.160.440
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
4ckjADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
4kba1QMCasein kinase I isoform delta2.7.11.10.440
4xivACPChemotaxis protein CheA2.7.13.30.440
9hvp0E9Gag-Pol polyprotein/0.440