scPDB - Distribution of Binding site Similarity values of 1ohj entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1ohj	COP	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1ohj	COP	Dihydrofolate reductase	1.5.1.3	1.000
4keb	FOL	Dihydrofolate reductase	1.5.1.3	0.614
1hfr	MOT	Dihydrofolate reductase	1.5.1.3	0.592
3l3r	OAG	Dihydrofolate reductase	1.5.1.3	0.586
3ghw	GHW	Dihydrofolate reductase	1.5.1.3	0.573
2w3m	FOL	Dihydrofolate reductase	1.5.1.3	0.571
1u72	MTX	Dihydrofolate reductase	1.5.1.3	0.567
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.566
4kak	06U	Dihydrofolate reductase	1.5.1.3	0.562
3nxt	D2E	Dihydrofolate reductase	1.5.1.3	0.558
1hfq	MOT	Dihydrofolate reductase	1.5.1.3	0.557
4m6l	21V	Dihydrofolate reductase	1.5.1.3	0.550
1hfp	MOT	Dihydrofolate reductase	1.5.1.3	0.546
3gi2	GHW	Dihydrofolate reductase	1.5.1.3	0.546
1ohk	COP	Dihydrofolate reductase	1.5.1.3	0.541
3gyf	51P	Dihydrofolate reductase	1.5.1.3	0.539
4m6k	FOL	Dihydrofolate reductase	1.5.1.3	0.539
4kbn	25U	Dihydrofolate reductase	1.5.1.3	0.530
1kms	LIH	Dihydrofolate reductase	1.5.1.3	0.524
1pd8	CO4	Dihydrofolate reductase	1.5.1.3	0.524
1s3u	TQD	Dihydrofolate reductase	1.5.1.3	0.523
3ntz	3TZ	Dihydrofolate reductase	1.5.1.3	0.517
4ky4	04J	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.516
3k45	51P	Dihydrofolate reductase	1.5.1.3	0.514
4kfj	FOL	Dihydrofolate reductase	1.5.1.3	0.513
4eil	FOL	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.510
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.502
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.501
4kd7	9DR	Dihydrofolate reductase	1.5.1.3	0.501
1kmv	LII	Dihydrofolate reductase	1.5.1.3	0.495
1drf	FOL	Dihydrofolate reductase	1.5.1.3	0.494
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.493
3ghv	GHC	Dihydrofolate reductase	1.5.1.3	0.491
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.490
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.490
3nu0	3TU	Dihydrofolate reductase	1.5.1.3	0.489
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.488
3jsu	KA5	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.487
4kfj	1R0	Dihydrofolate reductase	1.5.1.3	0.485
3d80	Q22	Dihydrofolate reductase	1.5.1.3	0.484
3nxv	D2F	Dihydrofolate reductase	1.5.1.3	0.484
3k47	D09	Dihydrofolate reductase	1.5.1.3	0.481
4ixe	IXE	Dihydrofolate reductase	1.5.1.3	0.478
1pd9	CO4	Dihydrofolate reductase	1.5.1.3	0.472
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.471
1mvs	DTM	Dihydrofolate reductase	1.5.1.3	0.469
3nxo	D2B	Dihydrofolate reductase	1.5.1.3	0.469
3qly	55V	Uncharacterized protein	/	0.467
1mvt	DTM	Dihydrofolate reductase	1.5.1.3	0.464
1u70	MTX	Dihydrofolate reductase	1.5.1.3	0.463
1dr4	HBI	Dihydrofolate reductase	1.5.1.3	0.462
1dlr	MXA	Dihydrofolate reductase	1.5.1.3	0.460
1cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.457
1boz	PRD	Dihydrofolate reductase	1.5.1.3	0.455
1vj3	TAB	Dihydrofolate reductase	1.5.1.3	0.451
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.450
3cse	N22	Uncharacterized protein	/	0.449
1dls	MTX	Dihydrofolate reductase	1.5.1.3	0.448
1j3i	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.447
2fzh	DH1	Dihydrofolate reductase	1.5.1.3	0.447
3iro	2CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.447
3inv	C50	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.446
3nxr	D2D	Dihydrofolate reductase	1.5.1.3	0.446
1s3w	TQT	Dihydrofolate reductase	1.5.1.3	0.443
3um5	CP6	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.443
4h97	53S	Dihydrofolate reductase	1.5.1.3	0.441