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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.84

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.841.000
3nx4NAPPutative oxidoreductase/0.598
3jynNDPQuinone oxidoreductase/0.511
1qorNDPQuinone oxidoreductase 1/0.496
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.480
4jbiNDPAlcohol dehydrogenase (Zinc)/0.470
3qwbNDPProbable quinone oxidoreductase1.6.5.50.467
3slkNDPPolyketide synthase extender module 2/0.459
2vnaNAPProstaglandin reductase 21.3.1.480.449
5dp2NAPCurF/0.444