Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1njdUMPThymidylate synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1njdUMPThymidylate synthase/1.000
2g86UMPThymidylate synthase/0.644
1bp6UMPThymidylate synthase/0.629
1jmiUMPThymidylate synthase/0.592
1jmgUMPThymidylate synthase/0.585
2tdmUMPThymidylate synthase/0.581
1tsyUMPThymidylate synthase/0.574
2g89UMPThymidylate synthase/0.566
2g8aUMPThymidylate synthase/0.566
1vzbUMPThymidylate synthase/0.565
1jmfUMPThymidylate synthase/0.564
1tsvUMPThymidylate synthase/0.544
1tsxUMPThymidylate synthase/0.543
1njbUMPThymidylate synthase/0.538
1njeDCMThymidylate synthase/0.538
1bpjUMPThymidylate synthase/0.527
1njcDCMThymidylate synthase/0.524
1jmhUMPThymidylate synthase/0.521
1njaDCMThymidylate synthase/0.500
1bidUMPThymidylate synthase/0.491
1lcbTMPThymidylate synthase/0.473
3bgxTMPThymidylate synthase/0.458
4dpdUMPBifunctional dihydrofolate reductase-thymidylate synthase/0.453
2vetUMPThymidylate synthase/0.447
1aobDDUThymidylate synthase/0.446
1vzaUMPThymidylate synthase/0.446