sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ndj | BTN | Streptavidin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1ndj | BTN | Streptavidin | / | 1.000 | |
| 1n43 | BTN | Streptavidin | / | 0.726 | |
| 1swe | BTN | Streptavidin | / | 0.666 | |
| 1mep | BTN | Streptavidin | / | 0.660 | |
| 1swp | BTQ | Streptavidin | / | 0.642 | |
| 1nc9 | IMI | Streptavidin | / | 0.634 | |
| 1n9m | BTN | Streptavidin | / | 0.629 | |
| 1swn | BTN | Streptavidin | / | 0.625 | |
| 2zsc | BTN | Tamavidin2 | / | 0.612 | |
| 1swd | BTN | Streptavidin | / | 0.609 | |
| 3wyp | BSO | Streptavidin | / | 0.609 | |
| 3ry2 | BTN | Streptavidin | / | 0.599 | |
| 4yvb | BTN | Streptavidin | / | 0.597 | |
| 1mk5 | BTN | Streptavidin | / | 0.587 | |
| 1sre | HAB | Streptavidin | / | 0.587 | |
| 2izf | BTN | Streptavidin | / | 0.587 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.586 | |
| 4ggz | BTN | Bll1558 protein | / | 0.586 | |
| 1stp | BTN | Streptavidin | / | 0.585 | |
| 1nqm | BTN | Streptavidin | / | 0.578 | |
| 1srg | MHB | Streptavidin | / | 0.576 | |
| 4gd9 | BTN | Streptavidin | / | 0.575 | |
| 1sri | DMB | Streptavidin | / | 0.572 | |
| 2rtg | BTN | Streptavidin | / | 0.569 | |
| 2rtf | BTN | Streptavidin | / | 0.567 | |
| 1lcw | SHM | Streptavidin | / | 0.564 | |
| 4bx7 | B4F | Streptavidin | / | 0.563 | |
| 2izg | BTN | Streptavidin | / | 0.560 | |
| 2izh | BTN | Streptavidin | / | 0.558 | |
| 2rtq | IMI | Streptavidin | / | 0.558 | |
| 1df8 | BTN | Streptavidin | / | 0.554 | |
| 1swr | BTN | Streptavidin | / | 0.554 | |
| 1avd | BTN | Avidin | / | 0.553 | |
| 4bj8 | BTN | Avidin | / | 0.553 | |
| 1srh | MOB | Streptavidin | / | 0.550 | |
| 1swp | BTN | Streptavidin | / | 0.550 | |
| 1luq | BTN | Streptavidin | / | 0.547 | |
| 1swt | BTN | Streptavidin | / | 0.544 | |
| 2rtr | IMI | Streptavidin | / | 0.542 | |
| 2y3f | BTN | Streptavidin | / | 0.540 | |
| 2rtp | IMI | Streptavidin | / | 0.537 | |
| 4dne | DTB | Streptavidin | / | 0.537 | |
| 2izl | IMI | Streptavidin | / | 0.535 | |
| 2rtd | BTN | Streptavidin | / | 0.532 | |
| 3vhi | VHI | Avidin | / | 0.531 | |
| 2rto | IMI | Streptavidin | / | 0.530 | |
| 2rte | BTN | Streptavidin | / | 0.528 | |
| 3vhm | NPK | Avidin | / | 0.528 | |
| 2rtn | IMI | Streptavidin | / | 0.526 | |
| 3wzn | BTN | Streptavidin | / | 0.523 | |
| 1rxh | BNI | Streptavidin | / | 0.521 | |
| 1srf | MTB | Streptavidin | / | 0.521 | |
| 2rtm | IMI | Streptavidin | / | 0.521 | |
| 3vhh | VHH | Avidin | / | 0.521 | |
| 1srj | NAB | Streptavidin | / | 0.520 | |
| 2jgs | BTN | Avidin | / | 0.520 | |
| 3vgw | NVZ | Avidin | / | 0.520 | |
| 4gda | BTN | Streptavidin | / | 0.518 | |
| 3wyq | BTN | Streptavidin | / | 0.517 | |
| 1i9h | BNI | Streptavidin | / | 0.514 | |
| 2avi | BTN | Avidin | / | 0.514 | |
| 1lcz | BH7 | Streptavidin | / | 0.512 | |
| 4z28 | BTN | Hoefavidin | / | 0.502 | |
| 3rdq | DTB | Streptavidin | / | 0.501 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.500 | |
| 2uz2 | BTN | Avd protein | / | 0.500 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.499 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 2c4i | BTN | Avidin | / | 0.497 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.497 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.496 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.492 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.489 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.489 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.487 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.487 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.486 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.484 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.484 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 1c7o | PPG | Hemolysin | / | 0.479 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.479 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.478 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.478 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4buf | F36 | Tankyrase-2 | 2.4.2.30 | 0.478 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.477 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.477 | |
| 5dp2 | NAP | CurF | / | 0.476 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2uyw | BTN | Avd protein | / | 0.474 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.474 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.473 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.473 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.472 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.471 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.470 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.470 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.470 | |
| 2izj | BTN | Streptavidin | / | 0.470 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 4bui | W2E | Tankyrase-2 | 2.4.2.30 | 0.470 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.469 | |
| 2izi | BTN | Streptavidin | / | 0.469 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1lke | DOG | Bilin-binding protein | / | 0.468 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.468 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.468 | |
| 4e32 | DWN | Methyltransferase | / | 0.468 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.468 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.467 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 3klb | FMN | Uncharacterized protein | / | 0.467 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.467 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.467 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.467 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.466 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.466 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.466 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.465 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.465 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.465 | |
| 3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.465 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.465 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.464 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.464 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.463 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.463 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.463 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.463 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.463 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 2r8p | T6F | Transketolase 1 | / | 0.462 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.462 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.462 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4bus | 32F | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 4hkk | AGI | Tankyrase-2 | 2.4.2.30 | 0.462 | |
| 4iei | ADP | Gene 2 protein | / | 0.462 | |
| 5epo | TUD | 7-alpha-hydroxysteroid deydrogenase | / | 0.462 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.461 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.461 | |
| 1bx9 | GLY_GGL_FOE | Glutathione S-transferase F2 | 2.5.1.18 | 0.460 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.460 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.460 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.459 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.459 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.459 | |
| 4k4f | K4F | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.458 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.458 | |
| 4bue | JQF | Tankyrase-2 | 2.4.2.30 | 0.458 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.458 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.457 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.457 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.457 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4e2z | JHZ | Methyltransferase | / | 0.457 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.456 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.456 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.456 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
| 4xmx | BES | Aminopeptidase N | 3.4.11.2 | 0.456 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.455 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.455 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.455 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4rrd | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.455 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.454 | |
| 2bjh | FER | Feruloyl esterase A | 3.1.1.73 | 0.454 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.454 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.454 | |
| 3ies | M24 | Luciferin 4-monooxygenase | 1.13.12.7 | 0.454 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.454 | |
| 4e2y | JHZ | Methyltransferase | / | 0.454 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.454 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.453 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.453 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 4l34 | 1VG | Tankyrase-2 | 2.4.2.30 | 0.453 | |
| 4phl | PIL | Phosphodiesterase | / | 0.453 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.452 | |
| 1ecb | 5GP | Amidophosphoribosyltransferase | / | 0.452 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1m9h | NAD | 2,5-diketo-D-gluconic acid reductase A | 1.1.1.346 | 0.452 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.452 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.452 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.452 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.452 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.451 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.451 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.451 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.451 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.451 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.450 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2mm3 | CHO | Gastrotropin | / | 0.450 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.450 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4hlk | 431 | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.450 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.450 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.449 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.449 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.449 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 2imk | GTX | AGAP009194-PA | / | 0.449 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.449 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.449 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3eks | CY9 | Actin-5C | / | 0.449 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.449 | |
| 4pnr | G18 | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.449 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.448 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.448 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4c4o | NAD | SADH | / | 0.448 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.448 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.448 | |
| 1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.447 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.447 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.447 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.447 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.446 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.446 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.446 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.445 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.445 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.445 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.445 | |
| 2r8o | T5X | Transketolase 1 | / | 0.445 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.445 | |
| 3up0 | D7S | aceDAF-12 | / | 0.445 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.445 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.444 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1zw1 | TN5 | Enoyl-ACP reductase | / | 0.444 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.444 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.444 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4k4e | K4E | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.443 | |
| 1ye6 | NAP | NAD(P)H-dependent D-xylose reductase | 1.1.1.307 | 0.443 | |
| 2rti | GLL | Streptavidin | / | 0.443 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.443 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.443 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 4xo7 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.442 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.442 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.442 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.442 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.442 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.442 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.442 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.442 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.442 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4xvy | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.442 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.441 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.441 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.441 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.441 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.441 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.441 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.441 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
| 4h6p | FMN | Chromate reductase | / | 0.441 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.441 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.441 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.441 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.440 | |
| 1pz1 | NAP | General stress protein 69 | / | 0.440 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.440 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.440 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2h2e | SA8 | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.440 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.440 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.440 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.440 | |
| 3ska | 053 | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.440 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.440 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.440 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.440 |