sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1m7b | GTP | Rho-related GTP-binding protein RhoE |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 1.000 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.605 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.526 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.506 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.505 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.496 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.490 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.483 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.482 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.481 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.481 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.481 | |
| 4mit | GTP | Rho-related protein racC | / | 0.477 | |
| 3oiv | GNP | GTPase HRas | / | 0.476 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.470 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.466 | |
| 1s1c | GNP | Transforming protein RhoA | / | 0.465 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.461 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.460 | |
| 4nyi | GNP | GTPase HRas | / | 0.460 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.458 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.458 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.457 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.457 | |
| 2rge | GNP | GTPase HRas | / | 0.456 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.455 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.454 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.449 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.448 | |
| 4xvr | GNP | GTPase HRas | / | 0.448 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.447 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.447 | |
| 2ic5 | GNP | Ras-related C3 botulinum toxin substrate 3 | / | 0.443 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.441 |