sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.797 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.735 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.715 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.661 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.660 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.653 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.634 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.633 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.629 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.627 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.624 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.619 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.619 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.614 | |
| 3cse | N22 | Uncharacterized protein | / | 0.613 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.609 | |
| 3eek | 53S | Uncharacterized protein | / | 0.605 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.605 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.603 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.598 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.597 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.596 | |
| 3qly | 55V | Uncharacterized protein | / | 0.596 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.594 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.594 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.592 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.591 | |
| 3eem | 53V | Uncharacterized protein | / | 0.590 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.586 | |
| 3eej | 53R | Uncharacterized protein | / | 0.583 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.580 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.579 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.578 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.577 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.577 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.576 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.575 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.572 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.571 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.571 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.570 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.570 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.565 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.560 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.560 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.559 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 3eel | 53T | Uncharacterized protein | / | 0.557 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.556 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.553 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.552 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.551 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.550 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.549 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.548 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.547 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.540 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.538 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.536 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.536 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.535 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.535 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.533 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.532 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.531 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.530 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.530 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.529 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.529 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 4p68 | MTX | Dihydrofolate reductase | / | 0.527 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.526 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.524 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.524 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 7dfr | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.522 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.521 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.521 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.520 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.520 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.516 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.514 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.513 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.510 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.506 | |
| 1dre | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 4m7v | RAR | Dihydrofolate reductase | / | 0.503 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.502 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.502 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.499 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.496 | |
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.494 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.492 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1rx2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.488 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.488 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 1ra2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.487 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.486 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.484 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.483 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.482 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.482 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.481 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.480 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.480 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.480 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.480 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.480 | |
| 1zky | 689 | Estrogen receptor | / | 0.479 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1rh3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.477 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.476 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4j26 | EST | Estrogen receptor beta | / | 0.476 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.475 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.475 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.474 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.473 | |
| 2g44 | T3O | Estrogen receptor | / | 0.473 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.473 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.473 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.473 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 2jfa | RAL | Estrogen receptor | / | 0.472 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.472 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.472 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.472 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.471 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.471 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.470 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.469 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.468 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.468 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1fml | RTL | Retinol dehydratase | / | 0.467 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.467 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.467 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.467 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.467 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.466 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.466 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.466 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.466 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.465 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 1xpc | AIT | Estrogen receptor | / | 0.464 | |
| 2fai | 459 | Estrogen receptor | / | 0.464 | |
| 3lu8 | IQX | Serum albumin | / | 0.464 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.463 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.463 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.463 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.463 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.463 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.462 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3ant | S82 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.462 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.462 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.461 | |
| 1l2i | ETC | Estrogen receptor | / | 0.461 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.461 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.461 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.461 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.460 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2b1z | 17M | Estrogen receptor | / | 0.460 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.460 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.460 | |
| 3wgw | T2B | Proliferating cell nuclear antigen | / | 0.460 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.460 | |
| 2p15 | EZT | Estrogen receptor | / | 0.459 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.459 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.459 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1yim | CM4 | Estrogen receptor | / | 0.458 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.458 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.458 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 1t47 | NTD | 4-hydroxyphenylpyruvate dioxygenase | 1.13.11.27 | 0.457 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.457 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.457 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.457 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.457 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.457 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.457 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.457 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.457 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 4zas | TYD | CalS13 | / | 0.457 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.456 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.456 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.456 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.456 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.456 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.456 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.456 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 3p9t | TCL | Repressor | / | 0.456 | |
| 3q95 | ESL | Estrogen receptor | / | 0.456 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.456 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.456 | |
| 1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.455 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.455 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.455 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.455 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.455 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.455 | |
| 4l8u | 9AZ | Serum albumin | / | 0.455 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.454 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.454 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 2ocf | EST | Estrogen receptor | / | 0.454 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.454 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.454 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.454 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.454 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.454 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.453 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.453 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.453 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.453 | |
| 3aba | FLI | Cytochrome P450 | / | 0.453 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.453 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.453 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.453 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.453 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 5dx3 | EST | Estrogen receptor | / | 0.453 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.452 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1x7e | 244 | Estrogen receptor | / | 0.452 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.452 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.452 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.452 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 3gep | 24H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.452 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.452 | |
| 3oll | EST | Estrogen receptor beta | / | 0.452 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.452 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.452 | |
| 1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.451 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.451 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.451 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.451 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.451 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.451 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.451 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.451 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.450 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.450 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.450 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.450 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.450 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.450 | |
| 3tdl | 11D | Serum albumin | / | 0.450 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.450 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.449 | |
| 1yin | CM3 | Estrogen receptor | / | 0.449 | |
| 1ysx | 4EB | Serum albumin | / | 0.449 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.449 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.449 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.449 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.449 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.449 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.449 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.449 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.448 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.448 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.448 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.448 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 4py6 | R78 | Bromodomain protein, putative | / | 0.448 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 4v12 | POG | MaoC like domain protein | / | 0.448 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.448 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.447 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.447 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.447 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.447 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.447 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.447 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.447 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4g1q | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 4xwt | U5P | Ribonuclease J | / | 0.447 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.447 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 1gwr | EST | Estrogen receptor | / | 0.446 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.446 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.446 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.446 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.446 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.446 | |
| 4o76 | 1M3 | Bromodomain-containing protein 4 | / | 0.446 | |
| 4tv3 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.446 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.446 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1nq0 | 4HY | Thyroid hormone receptor beta | / | 0.445 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1xp1 | AIH | Estrogen receptor | / | 0.445 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.445 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.445 | |
| 2w8y | NDR | Progesterone receptor | / | 0.445 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.445 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.445 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.445 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.445 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.445 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.445 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2ejz | SAH | Diphthine synthase | / | 0.444 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.444 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.444 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.444 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.444 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.444 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.444 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.444 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.444 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 4zn7 | DES | Estrogen receptor | / | 0.444 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.443 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.443 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.443 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.443 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.443 | |
| 4lb2 | DM5 | Serum albumin | / | 0.443 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.443 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.442 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1x7j | GEN | Estrogen receptor beta | / | 0.442 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cl5 | BIE | Catechol O-methyltransferase | 2.1.1.6 | 0.442 | |
| 2giu | FBR | Estrogen receptor beta | / | 0.442 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.442 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.442 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.442 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 3w9r | A8S | Abscisic acid receptor PYL9 | / | 0.442 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.441 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1eio | GCH | Gastrotropin | / | 0.441 | |
| 2jj3 | JJ3 | Estrogen receptor beta | / | 0.441 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.441 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.441 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.441 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.441 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.441 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.441 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.441 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4l9q | 9TP | Serum albumin | / | 0.441 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.441 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.440 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.440 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.440 | |
| 3d90 | NOG | Progesterone receptor | / | 0.440 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.440 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.440 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.440 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.440 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.440 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.440 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.440 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.440 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.440 | |
| 4jq8 | KJ8 | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.440 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.440 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.440 | |
| 4pd6 | URI | Nucleoside permease | / | 0.440 |