sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 1.000 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.619 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.561 | |
| 3sxn | COA | N-acetyltransferase Eis | / | 0.545 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.515 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.475 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.475 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.474 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.470 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.470 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.469 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.467 | |
| 4r87 | COA | Spermidine N(1)-acetyltransferase | / | 0.465 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.464 | |
| 1kux | CA3 | Serotonin N-acetyltransferase | / | 0.463 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.462 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.459 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.457 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.457 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.454 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.454 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.454 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.452 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.450 | |
| 4jxr | ACO | Acetyltransferase | / | 0.450 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.446 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1ppj | ANY | Cytochrome b | / | 0.446 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.445 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.445 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.444 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.442 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.441 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.441 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.441 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.440 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 |