sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1m2x | MCO | Metallo-beta-lactamase type 2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1m2x | MCO | Metallo-beta-lactamase type 2 | / | 1.000 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.491 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.488 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.468 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.466 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.460 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.455 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.452 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.449 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.443 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.443 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.441 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.440 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.440 |