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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1lp6C5POrotidine 5'-phosphate decarboxylase4.1.1.23

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1lp6C5POrotidine 5'-phosphate decarboxylase4.1.1.231.000
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.627
4nt03DUOrotidine 5'-phosphate decarboxylase4.1.1.230.583
2czfXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.545
2yyuC5POrotidine 5'-phosphate decarboxylase/0.519
3uwqU5POrotidine 5'-phosphate decarboxylase/0.509
2gejGDDPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.461
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.451
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.450
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.449
4nks2M2Fibroblast growth factor receptor 1/0.446