sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1lfd | GNP | GTPase HRas |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1lfd | GNP | GTPase HRas | / | 1.000 | |
| 4xvr | GNP | GTPase HRas | / | 0.537 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.520 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.517 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.486 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.480 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.463 | |
| 4dxa | GSP | Ras-related protein Rap-1b | / | 0.462 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.462 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.459 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.458 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.456 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.452 | |
| 3oiu | GNP | GTPase HRas | / | 0.450 | |
| 3v4f | GNP | GTPase HRas | / | 0.447 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.444 | |
| 4nyi | GNP | GTPase HRas | / | 0.444 | |
| 4nyj | GNP | GTPase HRas | / | 0.442 |