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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1l2sSTCBeta-lactamase3.5.2.6

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1l2sSTCBeta-lactamase3.5.2.61.000
1xgjHTCBeta-lactamase3.5.2.60.625
2r9w23CBeta-lactamase3.5.2.60.618
2pu2DK2Beta-lactamase3.5.2.60.599
1xgiNSTBeta-lactamase3.5.2.60.563
2r9xWH6Beta-lactamase3.5.2.60.513
4dc0NDPPutative ketoacyl reductase1.3.10.502
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.501
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.498
2gjlFMNNitronate monooxygenase1.13.12.160.494
2ikuLIYRenin3.4.23.150.494
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.494
3lpkZ76Beta-secretase 13.4.23.460.493
3qwbNDPProbable quinone oxidoreductase1.6.5.50.493
4opgFDAConserved Archaeal protein/0.493
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.491
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.490
1z7yAA5Cysteine synthase 12.5.1.470.488
3lqfNADGalactitol dehydrogenase/0.488
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.488
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.488
4yaoFMNNADPH--cytochrome P450 reductase/0.486
2fznFADBifunctional protein PutA1.5.5.20.484
4i0h1BLBeta-secretase 13.4.23.460.484
1h51FMNPentaerythritol tetranitrate reductase/0.483
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.483
4d89BXDBeta-secretase 13.4.23.460.483
1vf3GDNGlutathione S-transferase 32.5.1.180.481
2il2LIXRenin3.4.23.150.481
1guyNADMalate dehydrogenase/0.480
2oapANPType II secretion system protein (GspE-2)/0.480
1me6IVSPlasmepsin-23.4.23.390.478
1qorNDPQuinone oxidoreductase 1/0.478
1yqzCOACoenzyme A disulfide reductase/0.478
3f03FMNPentaerythritol tetranitrate reductase/0.478
4opiFDAConserved Archaeal protein/0.478
1o97FADElectron transfer flavoprotein subunit alpha/0.477
2hsdNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.477
2j09FMNDeoxyribodipyrimidine photo-lyase4.1.99.30.477
2c29NAPDihydroflavonol 4-reductase/0.476
1xe55FEPlasmepsin-23.4.23.390.475
2p83MR0Beta-secretase 13.4.23.460.475
3fktSIIBeta-secretase 13.4.23.460.475
4dfg0JVGag-Pol polyprotein3.4.23.160.475
1x7hNDPPutative ketoacyl reductase1.3.10.474
2a94AP0L-lactate dehydrogenase1.1.1.270.474
2g226IGRenin3.4.23.150.474
1xe65FPPlasmepsin-23.4.23.390.473
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.473
4nbwNADShort-chain dehydrogenase/reductase SDR/0.473
1f8fNADBenzyl alcohol dehydrogenase/0.472
3cib314Beta-secretase 13.4.23.460.472
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.472
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.471
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.471
1qrpHH0Pepsin A-43.4.23.10.471
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.471
2fj1CTCTetracycline repressor protein class D/0.471
2iko7IGRenin3.4.23.150.471
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.471
1obbNADAlpha-glucosidase3.2.1.200.470
1xs7MMIBeta-secretase 13.4.23.460.470
2b8l5HABeta-secretase 13.4.23.460.470
2g1o2IGRenin3.4.23.150.470
2p4j23IBeta-secretase 13.4.23.460.470
3cid318Beta-secretase 13.4.23.460.470
4eqsCOACoenzyme A disulfide reductase/0.470
1w6hTITPlasmepsin-23.4.23.390.469
3gw9VNILanosterol 14-alpha-demethylase/0.469
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.468
2iqgF2IBeta-secretase 13.4.23.460.468
2x7hPFNProstaglandin reductase 310.468
3b70NAPEnoyl reductase LovC10.468
4df2FMNNADPH dehydrogenase/0.468
4m4922YL-lactate dehydrogenase A chain1.1.1.270.468
4oplFDAConserved Archaeal protein/0.468
2g5cNADPrephenate dehydrogenase/0.467
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.467
4fm80UQBeta-secretase 13.4.23.460.467
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.467
4ke01R8Beta-secretase 13.4.23.460.467
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.466
2d29FADAcyl-CoA dehydrogenase/0.466
2f3fAXFBeta-secretase 13.4.23.460.466
2hm1LIQBeta-secretase 13.4.23.460.466
2xgs44PUncharacterized protein/0.466
3lqsPSZD-alanine aminotransferase2.6.1.210.466
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.466
4hwkNAPSepiapterin reductase1.1.1.1530.466
5jlaNADPutative short-chain dehydrogenase/reductase/0.466
1mj9COAHistone acetyltransferase ESA1/0.465
1mjbACOHistone acetyltransferase ESA1/0.465
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.465
1psa0ZLPepsin A3.4.23.10.465
1uxkNADMalate dehydrogenase/0.465
2givACOHistone acetyltransferase KAT8/0.465
2gv8NDPThiol-specific monooxygenase1.14.130.465
2zsaADPPantothenate kinase2.7.1.330.465
3duyAFJBeta-secretase 13.4.23.460.465
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.465
3lsiFADPyranose 2-oxidase/0.465
3n71SFGHistone-lysine N-methyltransferase Smyd1/0.465
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.465
4ambDUDPutative glycosyl transferase/0.465
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.464
2rabFADGlutathione amide reductase/0.464
3gvhNADMalate dehydrogenase/0.464
3lpiZ74Beta-secretase 13.4.23.460.464
1ur5NADMalate dehydrogenase/0.463
2e07SAHDiphthine synthase/0.463
2i7pACOPantothenate kinase 32.7.1.330.463
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.463
2ylzFADPhenylacetone monooxygenase1.14.13.920.463
3ai2NDPNADPH-sorbose reductase/0.463
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.463
3f63GTXGlutathione transferase GST1-4/0.463
3qlsNDPDihydrofolate reductase1.5.1.30.463
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.462
1ut6A8NAcetylcholinesterase3.1.1.70.462
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.462
2y0mACOHistone acetyltransferase KAT8/0.462
3lb8FADPutidaredoxin reductase1.18.1.50.462
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.462
3toxNAPPutative oxidoreductase/0.462
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
4exg916Beta-secretase 13.4.23.460.462
4m83ERYOleandomycin glycosyltransferase2.4.10.462
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.462
1g6kNADGlucose 1-dehydrogenase1.1.1.470.461
1h22E10Acetylcholinesterase3.1.1.70.461
1xvaSAMGlycine N-methyltransferase2.1.1.200.461
2hpvFMNFMN-dependent NADH-azoreductase1.70.461
2pncCLUPrimary amine oxidase, liver isozyme/0.461
3a3gDLZLumazine protein/0.461
3bgxTMPThymidylate synthase/0.461
3ohf3HFBeta-secretase 13.4.23.460.461
3qeoLLTDeoxycytidine kinase2.7.1.740.461
4dpwAGSMevalonate diphosphate decarboxylase/0.461
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.461
4eb7PLPCysteine desulfurase IscS 2/0.461
4opuFDAConserved Archaeal protein/0.461
1g1aNADdTDP-glucose 4,6-dehydratase/0.460
1icqFMN12-oxophytodienoate reductase 11.3.1.420.460
1tl7FOKAdenylate cyclase type 2/0.460
1tl7FOKAdenylate cyclase type 5/0.460
2abbFMNPentaerythritol tetranitrate reductase/0.460
2iyfERYOleandomycin glycosyltransferase2.4.10.460
3ai3NDPNADPH-sorbose reductase/0.460
3djjFADGlutathione reductase, mitochondrial1.8.1.70.460
3lsmSFDPyranose 2-oxidase/0.460
3ohh3HHBeta-secretase 13.4.23.460.460
3qe2FMNNADPH--cytochrome P450 reductase/0.460
3sufSUEPolyprotein/0.460
4k6fNAPPutative Acetoacetyl-CoA reductase/0.460
4q0kGA3Phytohormone-binding protein/0.460
5kwvANPPantothenate synthetase/0.460
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.459
3r96ACOMccE protein/0.459
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.459
3vdqNAD3-hydroxybutyrate dehydrogenase/0.459
4d0lGSPRas-related protein Rab-11A/0.459
4dbzNDPPutative ketoacyl reductase1.3.10.459
4eb5PLPCysteine desulfurase IscS 2/0.459
4jtqNAPAldo-keto reductase family 1 member C2/0.459
4q72FADBifunctional protein PutA/0.459
1bim0QBRenin3.4.23.150.458
1g63FMNEpidermin decarboxylase4.1.10.458
1kp3ATPArgininosuccinate synthase6.3.4.50.458
1mv8GDXGDP-mannose 6-dehydrogenase1.1.1.1320.458
1ozpACOMycothiol acetyltransferase2.3.1.1890.458
1t2cNAIL-lactate dehydrogenase1.1.1.270.458
2b58COADiamine acetyltransferase 1/0.458
2y6fM9FIsopenicillin N synthase1.21.3.10.458
3clsFADElectron transfer flavoprotein subunit alpha/0.458
3dv1AR9Beta-secretase 13.4.23.460.458
3q9bB3NAcetylpolyamine amidohydrolase/0.458
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.458
3veu0GOBeta-secretase 13.4.23.460.458
4b1bFADThioredoxin reductase1.8.1.90.458
5idwNAPShort-chain dehydrogenase/reductase SDR/0.458
1bil0IURenin3.4.23.150.457
1kqbFMNOxygen-insensitive NAD(P)H nitroreductase/0.457
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.457
2i4qUA4Renin3.4.23.150.457
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.457
3k5c0BIBeta-secretase 13.4.23.460.457
3kxw1ZZSaframycin Mx1 synthetase B/0.457
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.457
3tscNADUncharacterized protein/0.457
1h73ANPHomoserine kinase2.7.1.390.456
2c12FADNitroalkane oxidase1.7.3.10.456
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.456
2pswCOAN-alpha-acetyltransferase 50/0.456
2rqfJH3Hemolymph juvenile hormone binding protein/0.456
3b1dPLSBetaC-S lyase/0.456
3d91REMRenin3.4.23.150.456
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3h3qH13Collagen type IV alpha-3-binding protein/0.456
3uyk0CXProbable NDP-rhamnosyltransferase/0.456
3w8eNAD3-hydroxybutyrate dehydrogenase/0.456
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.456
4gid0GHBeta-secretase 13.4.23.460.456
4mlp2CXCryptochrome-2/0.456
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.456
4qecNAPElxO/0.456
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.455
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.455
1szgFNSCytochrome b2, mitochondrial1.1.2.30.455
2cv2GSUGlutamate--tRNA ligase6.1.1.170.455
2irzI02Beta-secretase 13.4.23.460.455
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.455
2zynBCDPeriplasmic binding protein/0.455
3bk2U5PRibonuclease J/0.455
3uylTYDProbable NDP-rhamnosyltransferase/0.455
4de00JBBeta-lactamase/0.455
4djy0KRBeta-secretase 13.4.23.460.455
4lcjNADC-terminal-binding protein 2/0.455
4q71FADBifunctional protein PutA/0.455
4x28FDAAcyl-CoA dehydrogenase FadE26/0.455
4x28FDAAcyl-CoA dehydrogenase FadE27/0.455
4z26FADPutative GMC-type oxidoreductase R13510.455
1tj0FADBifunctional protein PutA1.5.5.20.454
2c20NADUDP-glucose 4-epimerase/0.454
3f3sNADLambda-crystallin homolog/0.454
3oetNADErythronate-4-phosphate dehydrogenase/0.454
3p8zSAHGenome polyprotein2.1.1.560.454
3q43D66M1 family aminopeptidase3.4.110.454
3ua808WGlutamate receptor 2/0.454
4egbNADdTDP-glucose 4,6-dehydratase/0.454
4fsl0VBBeta-secretase 13.4.23.460.454
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.454
4j75TYMTryptophan--tRNA ligase/0.454
4kbyC2EStimulator of interferon genes protein/0.454
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.454
4oztP1AEcdysone receptor, putative/0.454
5irnADPNucleotide binding oligomerization domain containing 2/0.454
1lkeDOGBilin-binding protein/0.453
1tj1FADBifunctional protein PutA1.5.5.20.453
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.453
2ou2ACOHistone acetyltransferase KAT5/0.453
2vijC44Beta-secretase 13.4.23.460.453
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.453
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.453
3bg7FADPyranose 2-oxidase/0.453
3cic316Beta-secretase 13.4.23.460.453
3ixj586Beta-secretase 13.4.23.460.453
4bb3KKAIsopenicillin N synthase1.21.3.10.453
4blrUTPNTPase P4/0.453
4lxk1YTBeta-secretase 13.4.23.460.453
1dirNADDihydropteridine reductase1.5.1.340.452
1eq2NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.452
1f0xFADD-lactate dehydrogenase1.1.1.280.452
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.452
1svlADPLarge T antigen3.6.40.452
2c2aADPSensor histidine kinase/0.452
2d8aNADL-threonine 3-dehydrogenase/0.452
2freFMNNAD(P)H-flavin oxidoreductase/0.452
2fs4PZ1Renin3.4.23.150.452
2hizLIJBeta-secretase 13.4.23.460.452
3ixk929Beta-secretase 13.4.23.460.452
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3o26NDPSalutaridine reductase/0.452
3phiNDPShikimate dehydrogenase (NADP(+))/0.452
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.452
3skgPB8Beta-secretase 13.4.23.460.452
3vydVYDRenin3.4.23.150.452
4a81DXCMajor pollen allergen Bet v 1-A/0.452
4emtC2EStimulator of interferon genes protein/0.452
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.452
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.452
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.452
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.451
1g8jMGDArsenite oxidase subunit AioA1.20.9.10.451
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.451
1rneC60Renin3.4.23.150.451
2bf4FMNNADPH--cytochrome P450 reductase/0.451
2g1r3IGRenin3.4.23.150.451
2i7nACOPantothenate kinase 12.7.1.330.451
2igoFADPyranose 2-oxidase/0.451
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
3gwdFADCyclohexanone monooxygenase/0.451
3k5fAYHBeta-secretase 13.4.23.460.451
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.451
3nsh957Beta-secretase 13.4.23.460.451
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.451
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.451
4f4qFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.451
4i0i957Beta-secretase 13.4.23.460.451
5d3qGDPDynamin-13.6.5.50.451
1eveE20Acetylcholinesterase3.1.1.70.450
1lf3EH5Plasmepsin-23.4.23.390.450
1nzdUPGDNA beta-glucosyltransferase/0.450
1rwbNADGlucose 1-dehydrogenase1.1.1.470.450
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.450
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.450
2g1s4IGRenin3.4.23.150.450
2g247IGRenin3.4.23.150.450
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.450
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.450
4b1e6T6Beta-secretase 13.4.23.460.450
4dieC5PCytidylate kinase/0.450
4frkDWDBeta-secretase 13.4.23.460.450
4gddNAIUDP-galactopyranose mutase/0.450
4q73FADBifunctional protein PutA/0.450
4uugPXGBranched-chain amino acid aminotransferase, putative/0.450
5af7FADAcyl-CoA dehydrogenase/0.450
1h60STRPentaerythritol tetranitrate reductase/0.449
1qyvNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.449
1tehNADAlcohol dehydrogenase class-31.1.1.10.449
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.449
2dfvNADL-threonine 3-dehydrogenase/0.449
2g1y5IGRenin3.4.23.150.449
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.449
2rh9IGPTryptophan synthase alpha chain/0.449
2w3bNDPDihydrofolate reductase1.5.1.30.449
2w6cBM4Acetylcholinesterase3.1.1.70.449
2xlpFADPutative flavin-containing monooxygenase/0.449
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.449
3eksCY9Actin-5C/0.449
3fpzAHZThiamine thiazole synthase/0.449
3ig6438Urokinase-type plasminogen activator3.4.21.730.449
3r2fPB0Beta-secretase 13.4.23.460.449
3tog079Gag-Pol polyprotein2.7.7.490.449
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.449
4m9aFDAAcyl-CoA dehydrogenase/0.449
4o2rGDPGTP-binding protein Rheb/0.449
5ftfADPTPR domain protein/0.449
1ma0NADAlcohol dehydrogenase class-31.1.1.10.448
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.448
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.448
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.448
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.448
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.448
2dhfDZFDihydrofolate reductase1.5.1.30.448
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2ifaFMNUncharacterized protein/0.448
2iviACWIsopenicillin N synthase1.21.3.10.448
2ntrL00Beta-secretase 13.4.23.460.448
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.448
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.448
2xhd7T9Glutamate receptor 2/0.448
2xtnGTPGTPase IMAP family member 2/0.448
2ylrNAPPhenylacetone monooxygenase1.14.13.920.448
2zjmF1MBeta-secretase 13.4.23.460.448
3c3eGDP2-phospho-L-lactate transferase/0.448
3cltFADElectron transfer flavoprotein subunit alpha/0.448
3d84NDPDihydrofolate reductase1.5.1.30.448
3dmeFADPutative conserved exported protein/0.448
3h2sNDPPutative NADH-flavin reductase/0.448
3hl0NADMaleylacetate reductase/0.448
3k1wBFXRenin3.4.23.150.448
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.448
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.448
3udn09BBeta-secretase 13.4.23.460.448
4fryNADPutative signal-transduction protein with CBS domains/0.448
4hh4SAHCcbJ/0.448
4jx1CAHCamphor 5-monooxygenase1.14.15.10.448
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.448
5dp2NAPCurF/0.448
5jqhCAUBeta-2 adrenergic receptor/0.448
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.447
1x1bSAHC-20 methyltransferase/0.447
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.447
2dc1NADProbable L-aspartate dehydrogenase/0.447
2ejjSAHDiphthine synthase/0.447
2vbdV10Isopenicillin N synthase1.21.3.10.447
2vkeTACTetracycline repressor protein class D/0.447
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
3dm6757Beta-secretase 13.4.23.460.447
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.447
3h3t16HCollagen type IV alpha-3-binding protein/0.447
3mjeNDPAmphB/0.447
3pwwROCEndothiapepsin3.4.23.220.447
3qvsNADMyo-inositol-1-phosphate synthase (Ino1)/0.447
4cdmFO1Deoxyribodipyrimidine photolyase/0.447
4dptAGSMevalonate diphosphate decarboxylase/0.447
4ntdFADThioredoxin reductase/0.447
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.447
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.447
1fy7COAHistone acetyltransferase ESA1/0.446
1mjaCOAHistone acetyltransferase ESA1/0.446
1pq944BOxysterols receptor LXR-beta/0.446
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.446
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.446
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2o4cNADErythronate-4-phosphate dehydrogenase/0.446
2p20PRXAcetyl-coenzyme A synthetase/0.446
3ggoNAIPrephenate dehydrogenase/0.446
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.446
3ojxFMNNADPH--cytochrome P450 reductase/0.446
3p74FMNPentaerythritol tetranitrate reductase/0.446
3qt62P0Mevalonate diphosphate decarboxylase/0.446
3tjlFMNNADPH dehydrogenase/0.446
3vswR31Renin3.4.23.150.446
4a5lNDPThioredoxin reductase/0.446
4a8v2ANMajor pollen allergen Bet v 1-J/0.446
4ew2DXYTrifunctional purine biosynthetic protein adenosine-32.1.2.20.446
4f5yC2EStimulator of interferon genes protein/0.446
4i8zG08Gag-Pol polyprotein3.4.23.160.446
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.446
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.446
4jxrACOAcetyltransferase/0.446
4lisNADUDP-glucose 4-epimerase (Eurofung)/0.446
4qxp1YEStimulator of interferon genes protein/0.446
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.446
5fl3ADPPili retraction protein PilT/0.446
4ldeP0GBeta-2 adrenergic receptor/0.446
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
1njbUMPThymidylate synthase/0.445
2is0I03Beta-secretase 13.4.23.460.445
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.445
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2q3rFMN12-oxophytodienoate reductase 11.3.1.420.445
2xlsFADPutative flavin-containing monooxygenase/0.445
2y882ERPhosphoribosyl isomerase A5.3.1.160.445
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.445
3gqvNAPEnoyl reductase LovC10.445
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.445
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.445
3ov7ATPCCA-adding enzyme2.7.7.720.445
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.445
3vucHHERenin3.4.23.150.445
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.445
4c49HCYCorticosteroid-binding globulin/0.445
4c4oNADSADH/0.445
4e2zJHZMethyltransferase/0.445
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.445
4fse0VABeta-secretase 13.4.23.460.445
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.445
4jjiNADAlcohol dehydrogenase class-3/0.445
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.445
4mihFADPyranose 2-oxidase1.1.3.100.445
1lbcCYZGlutamate receptor 2/0.444
1n5dNDPCarbonyl reductase [NADPH] 1/0.444
1tu8GTXGlutathione S-transferase 22.5.1.180.444
2gvdFKPAdenylate cyclase type 2/0.444
2gvdFKPAdenylate cyclase type 5/0.444
2hdjNDPAldo-keto reductase family 1 member C2/0.444
2ien017Gag-Pol polyprotein3.4.23.160.444
2ignFADPyranose 2-oxidase/0.444
2yj4ATPCopper-transporting ATPase/0.444
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.444
3autNAIGlucose 1-dehydrogenase 41.1.1.470.444
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3h06VBPGlutamate receptor 2/0.444
3h3r14HCollagen type IV alpha-3-binding protein/0.444
3qdlFMNOxygen-insensitive NADPH nitroreductase/0.444
3qfaFADThioredoxin reductase 1, cytoplasmic1.8.1.90.444
4a83DXCMajor pollen allergen Bet v 1-A/0.444
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4xgiNADGlutamate dehydrogenase/0.444
1h2bNAJNAD-dependent alcohol dehydrogenase/0.443
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.443
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.443
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.443
2fiwACOGCN5-related N-acetyltransferase:Aminotransferase, class-II/0.443
2gsdNADFormate dehydrogenase/0.443
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.443
2p2mPRXAcetyl-coenzyme A synthetase/0.443
2rc4ACOHistone acetyltransferase KAT6A/0.443
2v59LZKBiotin carboxylase6.3.4.140.443
2yltFADPhenylacetone monooxygenase1.14.13.920.443
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.443
3mauEXTPutative sphingosine-1-phosphate lyase/0.443
3mk6ACOPantothenate kinase 32.7.1.330.443
3nl6ACPUncharacterized protein/0.443
3p8z36AGenome polyprotein2.1.1.560.443
3tr05GPGuanylate kinase/0.443
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3wqmB29Diterpene synthase3.1.7.80.443
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4araC56Acetylcholinesterase3.1.1.70.443
4ejmNAPPutative zinc-binding dehydrogenase/0.443
4j0v1H7Beta-secretase 13.4.23.460.443
4o8aFADBifunctional protein PutA1.2.1.880.443
4rvfTYDD-mycarose 3-C-methyltransferase/0.443
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4y8vADPAcyl-CoA synthetase (NDP forming)/0.443
1b8vNADMalate dehydrogenase/0.442
1c9k5GPBifunctional adenosylcobalamin biosynthesis protein CobU/0.442
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.442
1h74ADPHomoserine kinase2.7.1.390.442
1icqOPD12-oxophytodienoate reductase 11.3.1.420.442
1kkq471Peroxisome proliferator-activated receptor alpha/0.442
1sstCOASerine acetyltransferase2.3.1.300.442
1w4lGL8Acetylcholinesterase3.1.1.70.442
2g1n1IGRenin3.4.23.150.442
2gjnFMNNitronate monooxygenase1.13.12.160.442
2ob0ACON-alpha-acetyltransferase 50/0.442
3clrFADElectron transfer flavoprotein subunit alpha/0.442
3ekuCY9Actin-5C/0.442
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.442
4j7hTRHPCZA361.3/0.442
4k8s1QTBeta-secretase 13.4.23.460.442
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.442
5f12FMNNAD(P)H dehydrogenase (quinone)/0.442
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.442
1dhrNADDihydropteridine reductase1.5.1.340.441
1gcoNADGlucose 1-dehydrogenase1.1.1.470.441
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.441
1i5eU5PUracil phosphoribosyltransferase/0.441
1kfbIGPTryptophan synthase alpha chain/0.441
1pg3PRXAcetyl-coenzyme A synthetase/0.441
1qcwFNSCytochrome b2, mitochondrial1.1.2.30.441
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.441
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.441
1ypeUIPProthrombin3.4.21.50.441
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.441
2fhnBNIAvidin-related protein 4/5/0.441
2he5NDPAldo-keto reductase family 1 member C211.1.10.441
2ldbNADL-lactate dehydrogenase1.1.1.270.441
2npxNADNADH peroxidase1.11.1.10.441
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.441
2rlcCHDCholoylglycine hydrolase3.5.1.240.441
3cosNADAlcohol dehydrogenase 41.1.1.10.441
3em3478Gag-Pol polyprotein3.4.23.160.441
3kpbSAMUncharacterized protein MJ0100/0.441
3pm1ETHTH-type transcriptional regulator QacR/0.441
3qbhQBHBeta-secretase 13.4.23.460.441
3qgf46FGenome polyprotein2.7.7.480.441
3to6LYS_CMCHistone acetyltransferase ESA1/0.441
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.441
3wdsNADNADH-dependent quinuclidinone reductase/0.441
4dplNAPMalonyl-CoA reductase1.2.1.750.441
4dpuAGSMevalonate diphosphate decarboxylase/0.441
4ead0NPThymidine phosphorylase2.4.2.40.441
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.441
4pzrCOAHistone acetyltransferase p300/0.441
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.441
4rx6ATPNitrogen regulatory PII-like protein/0.441
4twnB96Ephrin type-A receptor 32.7.10.10.441
4xguADPPutative pachytene checkpoint protein 2/0.441
4yagNAIC alpha-dehydrogenase/0.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.440
1nahNADUDP-glucose 4-epimerase5.1.3.20.440
1o6zNADMalate dehydrogenase/0.440
1tj2FADBifunctional protein PutA1.5.5.20.440
1tqf32PBeta-secretase 13.4.23.460.440
1u4oNDDL-lactate dehydrogenase1.1.1.270.440
2f3eAXQBeta-secretase 13.4.23.460.440
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.440
2fzwNADAlcohol dehydrogenase class-31.1.1.10.440
2g94ZPQBeta-secretase 13.4.23.460.440
2j3qTFLAcetylcholinesterase3.1.1.70.440
2xfiXFIBeta-secretase 13.4.23.460.440
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.440
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.440
3aezGDPPantothenate kinase2.7.1.330.440
3k5dXLIBeta-secretase 13.4.23.460.440
3t6iNC8Endothiapepsin3.4.23.220.440
3tjzGNPADP-ribosylation factor 1/0.440
3tneRITCandidapepsin-13.4.23.240.440
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.440
4a6rTA8Probable aminotransferase/0.440
4h1vGNPDynamin-1-like protein3.6.5.50.440
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.440