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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1kolNADGlutathione-independent formaldehyde dehydrogenase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1kolNADGlutathione-independent formaldehyde dehydrogenase/1.000
2dphNADFormaldehyde dismutase/0.531
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.469
5cdsNAJAlcohol dehydrogenase E chain1.1.1.10.463
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.462
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.456
1ht0NADAlcohol dehydrogenase 1C1.1.1.10.453
4nfhNAJAlcohol dehydrogenase E chain1.1.1.10.453
2ohxNADAlcohol dehydrogenase E chain1.1.1.10.452
1f8fNADBenzyl alcohol dehydrogenase/0.444
1a71NADAlcohol dehydrogenase E chain1.1.1.10.441