sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 1.000 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.648 | |
| 3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 | / | 0.622 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.601 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.595 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.588 | |
| 1a69 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.576 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.575 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.574 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.571 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.567 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.563 | |
| 4ts3 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.562 | |
| 4ts9 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.561 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.547 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.543 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.528 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.526 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.525 | |
| 1pk9 | 2FA | Purine nucleoside phosphorylase DeoD-type | / | 0.520 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.520 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.520 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.515 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.514 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.513 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.510 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.505 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.492 | |
| 1odi | ADN | Purine nucleoside phosphorylase | / | 0.488 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.487 | |
| 1q1g | MTI | Purine nucleoside phosphorylase | / | 0.487 | |
| 2bsx | NOS | Purine nucleoside phosphorylase | / | 0.487 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.485 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.480 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.475 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.474 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.463 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.458 | |
| 3arv | SAU | Chitinase A | / | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.452 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.450 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.448 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.447 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.446 | |
| 4lde | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 5c93 | ACP | Two-component system histidine protein kinase | / | 0.444 | |
| 1tgv | 5UD | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.443 | |
| 3up0 | D7S | aceDAF-12 | / | 0.443 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.443 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.442 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.442 | |
| 4mka | 2AY | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.440 |