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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1k7fIAVTryptophan synthase alpha chain

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1k7fIAVTryptophan synthase alpha chain/1.000
2rh9IGPTryptophan synthase alpha chain/0.532
1kfcIPLTryptophan synthase alpha chain/0.522
4y6gF6FTryptophan synthase alpha chain/0.522
1qoqIGPTryptophan synthase alpha chain/0.521
4zqcF6FTryptophan synthase alpha chain/0.502
1kfbIGPTryptophan synthase alpha chain/0.473
2clfF6FTryptophan synthase alpha chain/0.472
2clmF6FTryptophan synthase alpha chain/0.457
2rhgIGPTryptophan synthase alpha chain/0.456
4wx2F6FTryptophan synthase alpha chain/0.449
4wx2F6FTryptophan synthase beta chain4.2.1.200.449
2cleF6FTryptophan synthase alpha chain/0.442