scPDB - Distribution of Binding site Similarity values of 1jr4 entry / Site 1

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1jr4	CL4	Catechol O-methyltransferase	2.1.1.6

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1jr4	CL4	Catechol O-methyltransferase	2.1.1.6	1.000
3a7d	FBN	Catechol O-methyltransferase	2.1.1.6	0.598
3nwe	662	Catechol O-methyltransferase	2.1.1.6	0.569
3r6t	LU1	Catechol O-methyltransferase	2.1.1.6	0.510
3nwb	659	Catechol O-methyltransferase	2.1.1.6	0.498
3ozt	OZZ	Catechol O-methyltransferase	2.1.1.6	0.497
3ozs	OZS	Catechol O-methyltransferase	2.1.1.6	0.488
3nw9	637	Catechol O-methyltransferase	2.1.1.6	0.454