scPDB - Distribution of Binding site Similarity values of 1jom entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1jom	FFO	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1jom	FFO	Dihydrofolate reductase	1.5.1.3	1.000
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.609
1rc4	DDF	Dihydrofolate reductase	1.5.1.3	0.586
4ej1	FOL	Dihydrofolate reductase	1.5.1.3	0.582
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.561
5cc9	DDF	Dihydrofolate reductase	1.5.1.3	0.561
5ccc	DDF	Dihydrofolate reductase	1.5.1.3	0.561
4i1n	FOL	Dihydrofolate reductase	1.5.1.3	0.560
1re7	FOL	Dihydrofolate reductase	1.5.1.3	0.556
1dds	MTX	Dihydrofolate reductase	1.5.1.3	0.549
4x5j	FOL	Dihydrofolate reductase	1.5.1.3	0.548
1tdr	MTX	Dihydrofolate reductase	1.5.1.3	0.545
1dra	MTX	Dihydrofolate reductase	1.5.1.3	0.526
1ddr	MTX	Dihydrofolate reductase	1.5.1.3	0.520
1rb3	MTX	Dihydrofolate reductase	1.5.1.3	0.520
2d0k	FOL	Dihydrofolate reductase	1.5.1.3	0.519
1drb	MTX	Dihydrofolate reductase	1.5.1.3	0.513
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.508
5hi6	MTX	Dihydrofolate reductase	/	0.508
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.507
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.505
2drc	MTX	Dihydrofolate reductase	1.5.1.3	0.504
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.504
1dis	BDM	Dihydrofolate reductase	1.5.1.3	0.503
1rx5	DDF	Dihydrofolate reductase	1.5.1.3	0.502
3och	2MX	Dihydrofolate reductase	1.5.1.3	0.501
4dfr	MTX	Dihydrofolate reductase	1.5.1.3	0.497
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.496
1rd7	FOL	Dihydrofolate reductase	1.5.1.3	0.492
1rg7	MTX	Dihydrofolate reductase	1.5.1.3	0.492
1rx6	DDF	Dihydrofolate reductase	1.5.1.3	0.490
4i13	FOL	Dihydrofolate reductase	1.5.1.3	0.489
1rx4	DDF	Dihydrofolate reductase	1.5.1.3	0.488
4elb	34S	Dihydrofolate reductase	/	0.488
4elh	53I	Dihydrofolate reductase	/	0.486
4xe6	06U	Dihydrofolate reductase	1.5.1.3	0.480
2qk8	MTX	Dihydrofolate reductase	/	0.479
4qi9	MTX	Dihydrofolate reductase	/	0.478
1bzf	TMQ	Dihydrofolate reductase	1.5.1.3	0.477
4g95	OAG	Dihydrofolate reductase	1.5.1.3	0.477
4ele	31I	Dihydrofolate reductase	/	0.475
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.472
2dhf	DZF	Dihydrofolate reductase	1.5.1.3	0.471
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.471
3fl8	RAR	Dihydrofolate reductase	/	0.466
3eig	MTX	Dihydrofolate reductase	1.5.1.3	0.464
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.462
4elb	34R	Dihydrofolate reductase	/	0.461
3fl9	TOP	Dihydrofolate reductase	/	0.460
4x5i	FOL	Dihydrofolate reductase	1.5.1.3	0.460
3tqb	FOL	Dihydrofolate reductase	/	0.459
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.458
3tda	PN0	Cytochrome P450 2D6	/	0.458
4elf	35I	Dihydrofolate reductase	/	0.458
3s3v	TOP	Dihydrofolate reductase	1.5.1.3	0.455
4elg	52J	Dihydrofolate reductase	/	0.454
3mpi	FAD	Glutaryl-CoA dehydrogenase	1.3.99.32	0.451
3s7a	684	Dihydrofolate reductase	1.5.1.3	0.451
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.451
4jlj	1NM	Deoxycytidine kinase	2.7.1.74	0.451
1rb2	FOL	Dihydrofolate reductase	1.5.1.3	0.450
1s3v	TQD	Dihydrofolate reductase	1.5.1.3	0.446
3nx4	NAP	Putative oxidoreductase	/	0.446
1dyi	FOL	Dihydrofolate reductase	1.5.1.3	0.445
3n0h	TOP	Dihydrofolate reductase	1.5.1.3	0.445
1dhf	FOL	Dihydrofolate reductase	1.5.1.3	0.442
5k2d	ZMA	Adenosine receptor A2a	/	0.440