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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1jnkANPMitogen-activated protein kinase 102.7.11.24

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1jnkANPMitogen-activated protein kinase 102.7.11.241.000
2xrwANPMitogen-activated protein kinase 82.7.11.240.481
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.478
4qnyANPMitogen activated protein kinase, putative/0.470
4lfiGNPCasein kinase II subunit alpha2.7.11.10.469
3kvxFMYMitogen-activated protein kinase 102.7.11.240.468
4deeADPAurora kinase A2.7.11.10.465
5dnrATPAurora kinase A2.7.11.10.465
4ux9ANPMitogen-activated protein kinase 82.7.11.240.456
4ej7ATPAminoglycoside 3'-phosphotransferase AphA1-IAB/0.446
1pmn984Mitogen-activated protein kinase 102.7.11.240.445