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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1jmfUMPThymidylate synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1jmfUMPThymidylate synthase/1.000
1jmiUMPThymidylate synthase/0.640
1tsyUMPThymidylate synthase/0.605
1jmgUMPThymidylate synthase/0.604
1njcDCMThymidylate synthase/0.604
2g86UMPThymidylate synthase/0.590
2g89UMPThymidylate synthase/0.586
1njaDCMThymidylate synthase/0.583
1njdUMPThymidylate synthase/0.574
1tsvUMPThymidylate synthase/0.563
2g8aUMPThymidylate synthase/0.553
1bp6UMPThymidylate synthase/0.536
1vzaUMPThymidylate synthase/0.534
1thyUMPThymidylate synthase/0.533
1njbUMPThymidylate synthase/0.531
1njeDCMThymidylate synthase/0.524
1jmhUMPThymidylate synthase/0.523
2tdmUMPThymidylate synthase/0.522
1lcbTMPThymidylate synthase/0.520
1vzbUMPThymidylate synthase/0.514
1bidUMPThymidylate synthase/0.512
1bpjUMPThymidylate synthase/0.506
1tsxUMPThymidylate synthase/0.505
3bgxTMPThymidylate synthase/0.482
1aobDDUThymidylate synthase/0.473
2vetUMPThymidylate synthase/0.473
1bduDURThymidylate synthase/0.466
1bp0UMPThymidylate synthase/0.446