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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.4

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.41.000
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.641
3urhFADDihydrolipoyl dehydrogenase/0.581
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.577
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.569
2yquFADDihydrolipoyl dehydrogenase/0.565
1zy8FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.558
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.556
2eq9FADDihydrolipoyl dehydrogenase/0.556
1lpfFADDihydrolipoyl dehydrogenase1.8.1.40.554
3ladFADDihydrolipoyl dehydrogenase/0.543
4jq9FADDihydrolipoyl dehydrogenase/0.536
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.523
1zx9FADMercuric reductase1.16.1.10.516
2eq8FADDihydrolipoyl dehydrogenase/0.509
1zk7FADMercuric reductase1.16.1.10.504
2r9zFADGlutathione amide reductase/0.497
2eq7FADDihydrolipoyl dehydrogenase/0.495
2a8xFADDihydrolipoyl dehydrogenase1.8.1.40.487
3ic9FADPutative dihydrolipoamide dehydrogenase/0.487
3cgbFADCoenzyme A disulfide reductase/0.466
1gerFADGlutathione reductase1.8.1.70.462
2eq6FADDihydrolipoyl dehydrogenase/0.462
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.462
1lvlFADDihydrolipoyl dehydrogenase1.8.1.40.459
3cgcFADCoenzyme A disulfide reductase/0.458
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.456
4ocgFADFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.456
1k0lFADp-hydroxybenzoate hydroxylase/0.455
1npxFADNADH peroxidase1.11.1.10.452
1nhpFADNADH peroxidase1.11.1.10.450
3icrFADCoenzyme A disulfide reductase/0.450
4nevFADTrypanothione reductase/0.449
1zmdFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.448
3qfbFADThioredoxin reductase 1, cytoplasmic1.8.1.90.448
1onfFADGlutathione reductase1.8.1.70.446
1h6vFADThioredoxin reductase 1, cytoplasmic1.8.1.90.444
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.444
1nhsFADNADH peroxidase1.11.1.10.444
2cfyFADThioredoxin reductase 1, cytoplasmic1.8.1.90.442
4j56FADThioredoxin reductase 21.8.1.90.440