scPDB - Distribution of Binding site Similarity values of 1itz entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1itz	TPP	Transketolase, chloroplastic	2.2.1.1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
1itz	TPP	Transketolase, chloroplastic	2.2.1.1	1.000
2r5n	TPP	Transketolase 1	/	0.611
1tka	N3T	Transketolase 1	2.2.1.1	0.599
3upt	TPP	Transketolase	/	0.595
1ay0	TPP	Transketolase 1	2.2.1.1	0.588
1trk	TPP	Transketolase 1	2.2.1.1	0.586
1tkb	N1T	Transketolase 1	2.2.1.1	0.579
1tkc	M6T	Transketolase 1	2.2.1.1	0.564
1ngs	TPP	Transketolase 1	2.2.1.1	0.555
3rim	TPP	Transketolase	2.2.1.1	0.503
2g25	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.490
2o1x	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.481
2o1s	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.476
2j9f	THV	2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial	1.2.4.4	0.471
2j9f	THV	2-oxoisovalerate dehydrogenase subunit beta, mitochondrial	1.2.4.4	0.471
3zht	TD9	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.464
1umc	TDP	2-oxoisovalerate dehydrogenase subunit alpha	1.2.4.4	0.456
1umc	TDP	2-oxoisovalerate dehydrogenase subunit beta	1.2.4.4	0.456
3zhs	TD6	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.445
2g8y	NAD	Hydroxycarboxylate dehydrogenase B	/	0.442