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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1ikyMSDGag-Pol polyprotein2.7.7.49

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1ikyMSDGag-Pol polyprotein2.7.7.491.000
1vruAAPGag-Pol polyprotein2.7.7.490.612
2ze2T27Gag-Pol polyprotein2.7.7.490.611
1tl1H18Gag-Pol polyprotein2.7.7.490.608
1ikxPNUGag-Pol polyprotein2.7.7.490.604
1ikwEFZGag-Pol polyprotein2.7.7.490.586
1s9eADBGag-Pol polyprotein2.7.7.490.579
3megT27Gag-Pol polyprotein2.7.7.490.579
3is9AC7Gag-Pol polyprotein2.7.7.490.578
1rt4UC1Gag-Pol polyprotein2.7.7.490.577
1tktH12Gag-Pol polyprotein2.7.7.490.577
3med65BGag-Pol polyprotein2.7.7.490.572
1revTB9Gag-Pol polyprotein2.7.7.490.570
1tkzH16Gag-Pol polyprotein2.7.7.490.570
1tl3H20Gag-Pol polyprotein2.7.7.490.565
1c1bGCAGag-Pol polyprotein2.7.7.490.558
2vg7NNIGag-Pol polyprotein2.7.7.490.558
1hnvTBOGag-Pol polyprotein2.7.7.490.557
1rt5UC2Gag-Pol polyprotein2.7.7.490.556
4i2pG73Gag-Pol polyprotein2.7.7.490.555
1hpzAAPGag-Pol polyprotein2.7.7.490.554
3meeT27Gag-Pol polyprotein2.7.7.490.553
3nbpJGZGag-Pol polyprotein2.7.7.490.553
4g1qT27Gag-Pol polyprotein2.7.7.490.552
1s6qTPBGag-Pol polyprotein2.7.7.490.551
4ifvT27Gag-Pol polyprotein2.7.7.490.551
2zd1T27Gag-Pol polyprotein2.7.7.490.550
1tkxGWBGag-Pol polyprotein2.7.7.490.549
2hnzPC0Gag-Pol polyprotein2.7.7.490.549
3m8p65BGag-Pol polyprotein2.7.7.490.548
3qlhT27Gag-Pol polyprotein2.7.7.490.547
4kko1REGag-Pol polyprotein2.7.7.490.546
4id5T27Gag-Pol polyprotein2.7.7.490.545
1s1wUC1Gag-Pol polyprotein2.7.7.490.543
3m8qDJZGag-Pol polyprotein2.7.7.490.541
1fk9EFZGag-Pol polyprotein2.7.7.490.540
3lamKRPGag-Pol polyprotein2.7.7.490.538
3irxUDRGag-Pol polyprotein2.7.7.490.534
4ko0JLJGag-Pol polyprotein2.7.7.490.533
1ikvEFZGag-Pol polyprotein2.7.7.490.532
1rt2TNKGag-Pol polyprotein2.7.7.490.532
1tvrTB9Gag-Pol polyprotein2.7.7.490.532
4ig3T27Gag-Pol polyprotein2.7.7.490.532
1hniAAAGag-Pol polyprotein2.7.7.490.531
4i2q1BTGag-Pol polyprotein2.7.7.490.531
1hquHBYGag-Pol polyprotein2.7.7.490.530
1rt7UC4Gag-Pol polyprotein2.7.7.490.530
2opqHBQGag-Pol polyprotein2.7.7.490.527
3i0sRT7Gag-Pol polyprotein2.7.7.490.524
3lanKBTGag-Pol polyprotein2.7.7.490.524
3i0rRT3Gag-Pol polyprotein2.7.7.490.523
2rf2MRXGag-Pol polyprotein2.7.7.490.522
1jlcFTCGag-Pol polyprotein2.7.7.490.520
2opsHBQGag-Pol polyprotein2.7.7.490.520
1eetBFUGag-Pol polyprotein2.7.7.490.518
3dmjGWEPol protein/0.517
3mec65BGag-Pol polyprotein2.7.7.490.517
2hndNVPGag-Pol polyprotein2.7.7.490.516
1jlqSBNGag-Pol polyprotein2.7.7.490.514
4rw6494Gag-Pol polyprotein2.7.7.490.511
2ban357Gag-Pol polyprotein2.7.7.490.510
3bgrT27Gag-Pol polyprotein2.7.7.490.507
3ffi3OBGag-Pol polyprotein2.7.7.490.507
1s1tUC1Gag-Pol polyprotein2.7.7.490.503
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.499
2vg5NNCGag-Pol polyprotein2.7.7.490.499
1jlaTNKGag-Pol polyprotein2.7.7.490.498
2ic3HBYGag-Pol polyprotein2.7.7.490.498
3gc9B45Mitogen-activated protein kinase 112.7.11.240.496
5cyqT27Gag-Pol polyprotein2.7.7.490.496
4kfbT27Gag-Pol polyprotein2.7.7.490.495
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.492
3h6k33TCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.491
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.490
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.487
2oppHBQGag-Pol polyprotein2.7.7.490.486
2c3qGTXGlutathione S-transferase theta-12.5.1.180.485
4o71CPBBromodomain-containing protein 4/0.485
1osvCHCBile acid receptor/0.484
4a83DXCMajor pollen allergen Bet v 1-A/0.483
4ogrADNCyclin-dependent kinase 92.7.11.220.482
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.481
1jlgUC1Gag-Pol polyprotein2.7.7.490.480
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
3zoiM2WIsopenicillin N synthase1.21.3.10.480
5uviZMAAdenosine receptor A2a/0.479
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.477
1bk0ACVIsopenicillin N synthase1.21.3.10.476
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.476
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.475
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.475
2hw2RFPRifampin ADP-ribosyl transferase/0.474
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.474
3pqbVGPPutative oxidoreductase/0.473
1uzwCDHIsopenicillin N synthase1.21.3.10.472
2jb4A14Isopenicillin N synthase1.21.3.10.472
4a81DXCMajor pollen allergen Bet v 1-A/0.472
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.472
1l2jETCEstrogen receptor beta/0.471
1o5rFR9Adenosine deaminase3.5.4.40.471
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
2vcmM11Isopenicillin N synthase1.21.3.10.471
1ot7IU5Bile acid receptor/0.470
1v7aFRCAdenosine deaminase3.5.4.40.470
2vn0TDZCytochrome P450 2C8/0.470
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
5k2aZMAAdenosine receptor A2a/0.470
5iua6DXAdenosine receptor A2a/0.470
1qiqACCIsopenicillin N synthase1.21.3.10.469
3s7a684Dihydrofolate reductase1.5.1.30.469
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4iae1DXAlr2278 protein/0.469
1fkoEFZGag-Pol polyprotein2.7.7.490.468
3vvpBNUUncharacterized protein/0.468
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
4j6bPLOCytochrome P450 monooxygenase/0.467
1xahNAD3-dehydroquinate synthase/0.466
1yinCM3Estrogen receptor/0.466
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.466
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
3ctj320Hepatocyte growth factor receptor2.7.10.10.466
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.466
3nalDBKCalcium-transporting ATPase/0.466
3r9dX6BCyclin-dependent kinase 22.7.11.220.466
3zkyWT4Isopenicillin N synthase1.21.3.10.466
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.465
4hfmNAP2-alkenal reductase (NADP(+)-dependent)/0.465
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.465
4q73FADBifunctional protein PutA/0.465
5k2bZMAAdenosine receptor A2a/0.465
1n4hREANuclear receptor ROR-beta/0.464
1qxlFR8Adenosine deaminase3.5.4.40.464
2wleCOAPolysialic acid O-acetyltransferase/0.464
3w0yDS4Vitamin D3 receptor/0.464
4i7fNVEGag-Pol polyprotein2.7.7.490.464
1hvyD16Thymidylate synthase2.1.1.450.463
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.463
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.463
2pmoHMDProtein kinase 7/0.463
3d0bSNXHeat shock protein HSP 90-alpha/0.463
3m0eATPTranscriptional regulator (NtrC family)/0.463
4ib4ERM5-hydroxytryptamine receptor 2B/0.463
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.463
2bxmIMNSerum albumin/0.462
2iviACWIsopenicillin N synthase1.21.3.10.462
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.462
2yee2ECHeat shock protein HSP 90-alpha/0.462
2ykeYKEHeat shock protein HSP 90-alpha/0.462
3bejMUFBile acid receptor/0.462
3dolGWIPol protein/0.462
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4iarERM5-hydroxytryptamine receptor 1B/0.462
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.462
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.462
1nq7ARLNuclear receptor ROR-beta/0.461
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.461
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.461
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.461
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.461
4jlj1NMDeoxycytidine kinase2.7.1.740.461
4nr42LKCREB-binding protein/0.461
4ucnMYAGlycylpeptide N-tetradecanoyltransferase/0.461
1oc1ASVIsopenicillin N synthase1.21.3.10.460
1oguST8Cyclin-dependent kinase 22.7.11.220.460
1uofPNNDeacetoxycephalosporin C synthase1.14.20.10.460
2vzmNRBCytochrome P450 monooxygenase PikC/0.460
3v94WYQPhosphodiesterase/0.460
4ap1NAPSteroid monooxygenase/0.460
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
1ndeMONEstrogen receptor beta/0.459
2yk2YJWHeat shock protein HSP 90-alpha/0.459
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.459
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.459
3vt5YI2Vitamin D3 receptor/0.459
1kb9SMACytochrome b/0.458
1sj0E4DEstrogen receptor/0.458
2c27ACOMycothiol acetyltransferase2.3.1.1890.458
2cig1DGDihydrofolate reductase1.5.1.30.458
2imfTOM2-hydroxychromene-2-carboxylate isomerase5.99.1.40.458
3hx4ANPCalmodulin-domain protein kinase 1/0.458
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4bbhNHWGlycylpeptide N-tetradecanoyltransferase/0.458
4eos1ROCyclin-dependent kinase 22.7.11.220.458
1db1VDXVitamin D3 receptor/0.457
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.457
1ezvSMACytochrome b/0.457
1uy8PU5Heat shock protein HSP 90-alpha/0.457
2hb8MVDVitamin D3 receptor/0.457
2jf9OHTEstrogen receptor/0.457
2npnSAMPutative cobalamin synthesis related protein/0.457
3hz5Z64Heat shock protein HSP 90-alpha/0.457
3mqe416Prostaglandin G/H synthase 21.14.99.10.457
3nr4PYVAbscisic acid receptor PYL2/0.457
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4b1fKRHGlutamate racemase/0.457
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.457
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.457
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.456
2cchATPCyclin-dependent kinase 22.7.11.220.456
2vbpVB1Isopenicillin N synthase1.21.3.10.456
2wotZZGTGF-beta receptor type-12.7.11.300.456
2xvv9DNSerum albumin/0.456
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.456
4c2yMYAGlycylpeptide N-tetradecanoyltransferase 1/0.456
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.456
1dajMOTDihydrofolate reductase1.5.1.30.455
1hb1OCVIsopenicillin N synthase1.21.3.10.455
1hb3SCVIsopenicillin N synthase1.21.3.10.455
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.455
2ovhAS0Progesterone receptor/0.455
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.455
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.455
2zjwREFCasein kinase II subunit alpha2.7.11.10.455
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.455
3mdvCL6Cholesterol 24-hydroxylase/0.455
3qlrQLRDihydrofolate reductase1.5.1.30.455
3vrwYS5Vitamin D3 receptor/0.455
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.455
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4ia7BIVVitamin D3 receptor A/0.455
4nmbFADBifunctional protein PutA/0.455
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.455
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.454
2x7f824TRAF2 and NCK-interacting protein kinase2.7.11.10.454
2yeiXQIHeat shock protein HSP 90-alpha/0.454
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.454
3t2zFADSulfide-quinone reductase/0.454
4a84DXCMajor pollen allergen Bet v 1-A/0.454
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
4eiyZMAAdenosine receptor A2a/0.454
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.454
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.453
2p1u4TNRetinoic acid receptor RXR-alpha/0.453
2uxpCLMHTH-type transcriptional regulator TtgR/0.453
3kpkFADSulfide-quinone reductase/0.453
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.453
4eerFMNPhototropin-22.7.11.10.453
4iaq2GM5-hydroxytryptamine receptor 1B/0.453
5iu4ZMAAdenosine receptor A2a/0.453
3emlZMAAdenosine receptor A2a/0.453
1e7qNAPGDP-L-fucose synthase/0.452
1fm4DXCMajor pollen allergen Bet v 1-L/0.452
1og5SWFCytochrome P450 2C9/0.452
1uyfPU1Heat shock protein HSP 90-alpha/0.452
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.452
2dvlFADAcyl-CoA dehydrogenase/0.452
2gpvOHTEstrogen-related receptor gamma/0.452
2uxoTACHTH-type transcriptional regulator TtgR/0.452
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.452
3icsADPCoenzyme A disulfide reductase/0.452
3iodA6DPantothenate synthetase6.3.2.10.452
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
3s79ASDAromatase1.14.14.140.452
3tk3CPZCytochrome P450 2B41.14.14.10.452
4apuA2KProgesterone receptor/0.452
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2aclREARetinoic acid receptor RXR-alpha/0.451
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3e01PZ2Gag-Pol polyprotein2.7.7.490.451
3mdmFJZCholesterol 24-hydroxylase/0.451
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4g1z0VPVitamin D3 receptor A/0.451
4nb6444Nuclear receptor ROR-gamma/0.451
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.451
1bwsNDPGDP-L-fucose synthase/0.450
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1kqwRTLCellular retinol-binding protein type II/0.450
1txiTX5Vitamin D3 receptor/0.450
2hc4VDXVitamin D3 receptor A/0.450
2i9pNAD3-hydroxyisobutyrate dehydrogenase, mitochondrial1.1.1.310.450
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
3at4CCKCasein kinase II subunit alpha2.7.11.10.450
3syiFADSulfide-quinone reductase/0.450
3zk5Z18Cytochrome P450 monooxygenase PikC/0.450
4a8v2ANMajor pollen allergen Bet v 1-J/0.450
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
4h9506UDihydrofolate reductase1.5.1.30.450
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.450
5cvfATPCasein kinase II subunit alpha2.7.11.10.450
5ikqJMSProstaglandin G/H synthase 21.14.99.10.450
5jtbZMAAdenosine receptor A2a/0.450
3rfmCFFAdenosine receptor A2a/0.450
1kt3RTLRetinol-binding protein 4/0.449
2cciATPCyclin-dependent kinase 22.7.11.220.449
2fwyH64Heat shock protein HSP 90-alpha/0.449
2hamC33Vitamin D3 receptor/0.449
2jn3JN3Fatty acid-binding protein, liver/0.449
3a1l2CCCytochrome P450/0.449
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.449
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3gbuATPUncharacterized sugar kinase PH14592.7.10.449
3gwfNAPCyclohexanone monooxygenase/0.449
3hz137DHeat shock protein HSP 90-alpha/0.449
3inwJZBHeat shock protein HSP 90-alpha/0.449
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.449
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3l6jZ90Alr2278 protein/0.449
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.449
4fhh0U3Vitamin D3 receptor A/0.449
4gmy0X5Tyrosine-protein kinase JAK2/0.449
1bsvNDPGDP-L-fucose synthase/0.448
1cqp803Integrin alpha-L/0.448
1ie8KH1Vitamin D3 receptor/0.448
1kzjCB3Thymidylate synthase/0.448
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1tw4CHDFatty acid-binding protein, liver/0.448
1zhwHC2Oxysterol-binding protein homolog 4/0.448
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2acwUPGGlycosyltransferase/0.448
2bxqIMNSerum albumin/0.448
2p33J07Mitogen-activated protein kinase 102.7.11.240.448
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.448
2rqfJH3Hemolymph juvenile hormone binding protein/0.448
2uzeC95Cyclin-dependent kinase 22.7.11.220.448
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.448
2w17I19Cyclin-dependent kinase 22.7.11.220.448
2ykcYKCHeat shock protein HSP 90-alpha/0.448
3m7rVDXVitamin D3 receptor/0.448
3mnrSD1Heat shock protein HSP 90-alpha/0.448
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.448
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4pkl1GHUncharacterized protein/0.448
4q0a4OAVitamin D3 receptor A/0.448
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.448
1aq1STUCyclin-dependent kinase 22.7.11.220.447
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.447
1ot7CHCBile acid receptor/0.447
1trgCB3Thymidylate synthase/0.447
1umlFR4Adenosine deaminase3.5.4.40.447
1uy6PU3Heat shock protein HSP 90-alpha/0.447
1xuoLA1Integrin alpha-L/0.447
2p4yC03Peroxisome proliferator-activated receptor gamma/0.447
2y60M8FIsopenicillin N synthase1.21.3.10.447
2ykbYKBHeat shock protein HSP 90-alpha/0.447
2ykiYKIHeat shock protein HSP 90-alpha/0.447
2zbaZBATrichothecene 3-O-acetyltransferase/0.447
3cgfJNFMitogen-activated protein kinase 102.7.11.240.447
3ddw055Glycogen phosphorylase, liver form2.4.1.10.447
3ez2ADPPlasmid partition protein A/0.447
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.447
3rkb12ZCyclin-dependent kinase 22.7.11.220.447
3tmz06XCytochrome P450 2B41.14.14.10.447
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.447
4jqh1MFAlr2278 protein/0.447
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.447
5dc5B3NHistone deacetylase 83.5.1.980.447
3reyXACAdenosine receptor A2a/0.447
3uzaT4GAdenosine receptor A2a/0.447
1s19MC9Vitamin D3 receptor/0.446
1upw444Oxysterols receptor LXR-beta/0.446
2ds11CDCyclin-dependent kinase 22.7.11.220.446
2h96893Mitogen-activated protein kinase 82.7.11.240.446
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
2w98P1ZProstaglandin reductase 21.3.1.480.446
2y6fM9FIsopenicillin N synthase1.21.3.10.446
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.446
3eel53TUncharacterized protein/0.446
3h0a9RARetinoic acid receptor RXR-alpha/0.446
3oafOAGDihydrofolate reductase1.5.1.30.446
3r6pA8SAbscisic acid receptor PYL10/0.446
3wv9FEGHmd co-occurring protein HcgE/0.446
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.446
4ez50RSCyclin-dependent kinase 62.7.11.220.446
4g2h0VQVitamin D3 receptor A/0.446
4jqeANPCasein kinase II subunit alpha2.7.11.10.446
4klaCHDFerrochelatase, mitochondrial4.99.1.10.446
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.446
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.446
5cu6ATPCasein kinase II subunit alpha2.7.11.10.446
5k2cZMAAdenosine receptor A2a/0.446
1ao8MTXDihydrofolate reductase1.5.1.30.445
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1iyzNDPProbable quinone oxidoreductase/0.445
1powFADPyruvate oxidase1.2.3.30.445
1uykPUXHeat shock protein HSP 90-alpha/0.445
1v0oINRCell division control protein 2 homolog2.7.11.220.445
2g44T3OEstrogen receptor/0.445
2vbdV10Isopenicillin N synthase1.21.3.10.445
3drcMTXDihydrofolate reductase1.5.1.30.445
3f82353Hepatocyte growth factor receptor2.7.10.10.445
3q9xEMOCasein kinase II subunit alpha2.7.11.10.445
3qm4PN0Cytochrome P450 2D6/0.445
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.445
3t14FADSulfide-quinone reductase/0.445
3vetADPnebramycin 5' synthase6.1.2.20.445
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4eoi1ROCyclin-dependent kinase 22.7.11.220.445
4kwi1TJReductase homolog/0.445
5ag7MYAGlycylpeptide N-tetradecanoyltransferase/0.445
4zj8SUVOrexin receptor type 1/0.445
1aoeGW3Dihydrofolate reductase1.5.1.30.444
1blzACVIsopenicillin N synthase1.21.3.10.444
1g4sTPSThiamine-phosphate synthase/0.444
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
1jutLYDThymidylate synthase/0.444
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.444
1pl8NADSorbitol dehydrogenase1.1.1.140.444
1uyePU9Heat shock protein HSP 90-alpha/0.444
1uyhPU0Heat shock protein HSP 90-alpha/0.444
2p7zOHTEstrogen-related receptor gamma/0.444
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.444
2yncYNCGlycylpeptide N-tetradecanoyltransferase/0.444
2zb45OPProstaglandin reductase 21.3.1.480.444
3amyAGICasein kinase II subunit alpha2.7.11.10.444
3cv9VDXVitamin D3 dihydroxylase/0.444
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3lfcZ86Mitogen-activated protein kinase 14/0.444
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fyn0VETyrosine-protein kinase SYK2.7.10.20.444
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.444
4nc3ERM5-hydroxytryptamine receptor 2B/0.444
4oavACP2-5A-dependent ribonuclease3.1.260.444
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
1qjfACSIsopenicillin N synthase1.21.3.10.443
2dqsTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.443
2po7CHDFerrochelatase, mitochondrial4.99.1.10.443
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.443
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.443
2ykjYKJHeat shock protein HSP 90-alpha/0.443
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.443
3dl9V2HVitamin D 25-hydroxylase/0.443
3gc8B45Mitogen-activated protein kinase 112.7.11.240.443
3ictADPCoenzyme A disulfide reductase/0.443
3kpzZNEVitamin D3 receptor/0.443
3nga3NGCasein kinase II subunit alpha2.7.11.10.443
3ojlNADCap5O/0.443
3vt9YI4Vitamin D3 receptor/0.443
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.443
4b7sQLECytochrome P450 monooxygenase PikC/0.443
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4j6cSTRCytochrome P450 monooxygenase/0.443
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.443
4o761M3Bromodomain-containing protein 4/0.443
4qknJMSAlpha-ketoglutarate-dependent dioxygenase FTO/0.443
4zasTYDCalS13/0.443
4z9g1Q5Corticotropin-releasing factor receptor 1/0.443
1df7MTXDihydrofolate reductase1.5.1.30.442
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1ek2CDUBifunctional epoxide hydrolase 2/0.442
1errRALEstrogen receptor/0.442
1hk1T44Serum albumin/0.442
1rkhVD2Vitamin D3 receptor/0.442
2h55DZ8Heat shock protein HSP 90-alpha/0.442
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2vu3LZECyclin-dependent kinase 22.7.11.220.442
3d7kD7KBenzaldehyde lyase/0.442
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
3dleGFAGag-Pol polyprotein2.7.7.490.442
3rmf20ZCyclin-dependent kinase 22.7.11.220.442
3s1dZIRCytokinin dehydrogenase 11.5.99.120.442
3t8xT8XT-cell surface glycoprotein CD1b/0.442
3w0aDS5Vitamin D3 receptor/0.442
3w5p4OAVitamin D3 receptor/0.442
4hni16WCasein kinase I isoform epsilon2.7.11.10.442
4ia1BIVVitamin D3 receptor A/0.442
4ivw1GJEstrogen receptor/0.442
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.442
5a3bAPRSIR2 family protein/0.442
1fmjRTLRetinol dehydratase/0.441
1obnASVIsopenicillin N synthase1.21.3.10.441
1tlcF89Thymidylate synthase/0.441
1uomPTIEstrogen receptor/0.441
1ygkRRCPyridoxal kinase2.7.1.350.441
2bheBRYCyclin-dependent kinase 22.7.11.220.441
2bj4OHTEstrogen receptor/0.441
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2hcdBIVVitamin D3 receptor A/0.441
2o4rVD5Vitamin D3 receptor/0.441
2yg4FADPutrescine oxidase/0.441
2zynBCDPeriplasmic binding protein/0.441
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.441
3k4nFADPyranose 2-oxidase/0.441
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
3nj0PYVAbscisic acid receptor PYL2/0.441
3q3cNADNAD-dependent L-serine dehydrogenase/0.441
3sw418KCyclin-dependent kinase 22.7.11.220.441
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.441
3wgwT2BProliferating cell nuclear antigen/0.441
3zdu38RCyclin-dependent kinase-like 32.7.11.220.441
4bcmT7ZCyclin-dependent kinase 22.7.11.220.441
4g1y0VOVitamin D3 receptor A/0.441
4gk4L90Ephrin type-A receptor 32.7.10.10.441
4oauADP2-5A-dependent ribonuclease3.1.260.441
4xe606UDihydrofolate reductase1.5.1.30.441
1dhiMTXDihydrofolate reductase1.5.1.30.440
1ep4S11Gag-Pol polyprotein2.7.7.490.440
1gqtACPRibokinase/0.440
1yc2NADNAD-dependent protein deacylase 2/0.440
1zdwFLVPrenyltransferase/0.440
2bu9HFVIsopenicillin N synthase1.21.3.10.440
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.440
2fziDH3Dihydrofolate reductase1.5.1.30.440
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2pupADPMethylthioribose kinase2.7.1.1000.440
2ynfWHUGag-Pol polyprotein2.7.7.490.440
2z7gEH9Adenosine deaminase3.5.4.40.440
2z97CAMCamphor 5-monooxygenase1.14.15.10.440
2znnS44Peroxisome proliferator-activated receptor alpha/0.440
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.440
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.440
3gobHXXDdmC/0.440
3h1jSMACytochrome b/0.440
3ibdCPZCytochrome P450 2B61.14.130.440
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3lu8IQXSerum albumin/0.440
3o0iP54Heat shock protein HSP 90-alpha/0.440
3pp1IZGDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3uli1N3Cyclin-dependent kinase 22.7.11.220.440
3w0c6DSVitamin D3 receptor/0.440
3w5tLHPVitamin D3 receptor/0.440
4aosNAPSteroid monooxygenase/0.440
4em9TCEPeroxisome proliferator-activated receptor gamma/0.440
4iah1DXAlr2278 protein/0.440
4iui1GQEstrogen receptor/0.440
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4uymVOR14-alpha sterol demethylase Cyp51B/0.440
4yaoFMNNADPH--cytochrome P450 reductase/0.440
5cshATPCasein kinase II subunit alpha2.7.11.10.440
5dq8FLFTranscriptional enhancer factor TEF-4/0.440
5hs1VORLanosterol 14-alpha demethylase/0.440
5iu86DZAdenosine receptor A2a/0.440